A microtomografia de raios X para o estudo da anatomia da microestrutura de órgãos e suas patologias

• Ano de defesa: 2021
• Autor(a) principal: Moreira, Adriana José da Penha
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal do Rio de Janeiro; Brasil; Instituto Alberto Luiz Coimbra de Pós-Graduação e Pesquisa de Engenharia; Programa de Pós-Graduação em Engenharia Nuclear; UFRJ
• Palavras-chave em Português: Tomografia computadorizada; Microtomografia; Raios X; Diagnóstico por imagem; Tomography; X-Ray Computed; Diagnostic imaging; CNPQ::ENGENHARIAS::ENGENHARIA NUCLEAR::APLICACOES DE RADIOISOTOPOS::INSTRUMENTACAO PARA MEDIDA E CONTROLE DE RADIACAO
• Link de acesso: http://hdl.handle.net/11422/27169

Computed microtomography has advanced in the last decades providing an improvement in the quality of the generated images, assisting in several fields of science, especially in studies involving biological samples. X-ray microtomography is a nondestructive technique that makes possible the 3D model reconstruction, allowing visualization of the internal microstructures of studied samples. In the medical field, the visualization of these microstructures in organs is essential to the human beings survival, as it favors the prevention, control and cure of diseases. However, biological samples are still studied through traditional microscopy, an invasive technique that leads to the destruction of the analyzed organs by cuts made by microtome. In this work, images were formed by two different microtomograph systems, which work in different voltage and current ranges. Nevertheless, the technique demonstrated competence through the Phoenix V|tomex|m microtomograph and allowed the formation of high resolution and excellent contrast images with its wide range of power, besides the visualization of internal microstructures of organs such as the cervix, the appendix and the fallopian tube. X-ray computed microtomography proved to be an excellent imaging technique for analysis performed on human organs, which until then were only analyzed using the traditional microscopy technique.