Pertinência da citologia anal em mulheres com lesão genital HPV-induzida

• Ano de defesa: 2016
• Autor(a) principal: Silva, Maria do Perpétuo Socorro Nobre Medeiros e
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Brasil; UFRN; PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS DA SAÚDE
• Palavras-chave em Português: Mulher; Câncer anal; Citologia; HPV; CNPQ::CIENCIAS DA SAUDE
• Link de acesso: https://repositorio.ufrn.br/jspui/handle/123456789/21469

The study was conducted as a requirement for obtaining the title of Master in the Health Sciences Program of the Federal University of Rio Grande do Norte. The program has a multidisciplinary proposal where we have the opportunity to exchange ideas and to know multi-professional experience, including subjects that expand our field of vision. The knowledge of topics such as analytical, scientific paper writing and educational practices were essential not to restrict our attention as a doctor. The survey produced three articles: the first one is a literature review through Pubmed portals, Embase, Scielo, Web of Science and CancerLit using keywords HPV, cytology, and anal cancer. The other articles resulted from data collected from a cross-sectional study in 200 women with and without genital lesions who were recruited for anal Pap smears. Women who had abnormal results from Atypical Squamous Cells were classified as abnormal anal cytology. The average age was 41 years. Most are non-white skin (56%), with up to eight years of education (50.5%) and non-smokers (91.5%). Regarding the description of contextual variables, 63.5% used contraceptive methods, 80% had been pregnant and of these, 30% had some abortion, most had up to three partners (73.5%) and did not report any previous STD (74%). More than half indicated that did not practice anal sex (75.5%), 91% stated that their partners did not have HPV, did not use drugs (87.5%) and not had bisexual relations (96.5%). Most women did not have any allergies (85%), anal pathology (92%) or anal bleeding (68.5%), but more than half had GSIL (genital squamous intraepithelial lesion) (57.5%) and a significant amount had abnormal anal cytology (13%). There was a significant association between abnormal anal cytology and GSIL (PR = 2.46; p = 0.032) demonstrating that is important to perform anal cytology in this group of patients.