Propriedades físicas e biológicas de sistemas adesivos autocondicionantes experimentais

• Ano de defesa: 2018
• Autor(a) principal: Lima, Rodolfo Xavier de Sousa
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Brasil; UFRN; PROGRAMA DE PÓS-GRADUAÇÃO EM SAÚDE COLETIVA
• Palavras-chave em Português: Citotoxicidade; Sistema adesivo experimental; Resistência flexural; CNPQ::CIENCIAS DA SAUDE::SAUDE COLETIVA
• Link de acesso: https://repositorio.ufrn.br/jspui/handle/123456789/26009

Objective: to evaluate the Clearence of Residual Monomers (CRM), flexural strength (FS), elastic modulus (EM) and cytotoxicity of experimental adhesives (EA) formulated based of GDMA-P. Methodology: the EA were divided into 9 groups, according to the following parameters: % of monomeric mass of GDMA-P GDMA-P/ HEMA/ UDMA (10/30/30; 20/30/20 e 30/30/10); mol % of photoinitiators CQ/BAPO/EDMAB/DH (1,0/0,0/1,0/0,2; 0,0/1,0/0,0/0,2; 0,5/0,5/1,0/0,2). For cytotoxicity, NIH-3T3 cells and MTT Assay and Alamar Blue tests were used (n=8). To measure RRM, 54 third molars were used to obtain a flat area of dentin (n=6) that received the adhesives and, after 24 h, the CRM was in HPLC. For FS and EM, followed by the method described in ISO 4049 (n = 7). Statistical analysis was performed with two-way ANOVA and post Tukey test (p <0.05). Results: for the % of reduction of Alamar Blue, between 10%, 20% and 30% there was no difference. Among the photoinitiators, CQ and BAPO, singly, presented better values for 30% and CQ + BAPO for the concentration 20%. For% cell viability through MTT Assay, there was no difference between photoinitiators and % GDMA-P. For CRM, for the same photoinitiators and different concentrations of GDMA-P, 10% of GDMA-P released more HEMA. For the different concentrations of GDMA-P and the same photoinitiators, the groups containing CQ released more HEMA. For UDMA, among the groups of photoinitiators, only CQ presented differences, being the percentage of 10% of GDMA-P that most released UDMA monomers. For the three concentrations of GDMA-P, CQ released more UDMA monomers. For the release of GDMA-P, among the same photoinitiators, the 10% concentration gave greater release of monomers to the groups containing CQ. Among the same concentrations and different photoinitiators, CQ provided greater release of GDMA-P to 10% and 30%. For the 20% concentration, BAPO allowed the highest release. For RF, 10% of GDMA-P presented differences between the photoinitiators, being the BAPO group the highest RF. The BAPO + CQ mixture allowed higher RF values for the 20% and 30%. For EM, 30% GDMA-P was the only one to present a significant difference, the BAPO + CQ group being the highest value. Conclusions: In general, CQ released more monomers, so that the 10% concentration of GDMA-P in association with the BAPO photoinitiator group was able to provide better results for the properties tested.