Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Albuquerque, Manuela Andrade de lattes
Orientador(a): Araújo, Karina Conceição Gomes Machado de
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Sergipe
Programa de Pós-Graduação: Pós-Graduação em Ciências da Saúde
Departamento: Não Informado pela instituição
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: https://ri.ufs.br/handle/riufs/3788
Resumo: Leprosy is a chronic, infectious and systemic disease caused by the bacillus Mycobacterium leprae, which can affect both genders, at all ages, leading to physical disabilities of several degrees. It is a worldwide sanitary problem and, in Brazil, is considered as endemic. The aim of this study was describe the clinical and epidemiological profiles of the disease, investigate the risk factors associated with the cases of leprosy, as well as analyze spatially the distribution of cases in the town of Nossa Senhora do Socorro. The study is observational and case-control. We considered as cases all the individuals diagnosed with leprosy who resided in the town and who were notified in the town´s Basic Heath Units and in Aracaju´s University Hospital and Center of Medical Specialties, in 2014. As control group, we considered individuals without diagnostic of the disease and who resided in the same house or in houses on the same street as the cases. For the data collection, we used the Inquiry on Risk Factors, the SINAN`s Leprosy Investigation/Notification Forms and the method of instantaneous positioning from a point collected by GPS. There was the analysis of the clinical and epidemiological variables, and the logistics regression described the association between the exposition variables and the leprosy cases. The average age found was 48.1±19 years and individuals were mostly male, brown-skinned and had multibacillary operational classification, with predominance of the Virchowian clinical form. We found a significant association between the presence of the current cases of leprosy in the town and the presence of other diseases in the individual, with infection through leprosy. Likewise, by analyzing schooling, family average income, presence of old cases of leprosy in the town and other diseases associated, a significant influence of such variables was observed upon the appearance of leprosy cases. The location of the leprosy cases showed heterogeneous spatial distribution in the town´s urban area. Also, four important clusters were observed in the region studied: two in the north and two in the south, highlighting the Marcos Freire II region. Socioeconomic factors may be associated with the leprosy cases in the town of Nossa Senhora do Socorro.
id UFS-2_fcff633886ab92f982eb79da17917aa9
oai_identifier_str oai:oai:ri.ufs.br:repo_01:riufs/3788
network_acronym_str UFS-2
network_name_str Repositório Institucional da UFS
repository_id_str
spelling Albuquerque, Manuela Andrade deAraújo, Karina Conceição Gomes Machado dehttp://lattes.cnpq.br/33712773857972212017-09-26T12:17:25Z2017-09-26T12:17:25Z2016-02-26ALBUQUERQUE, Manuela Andrade de. Perfil Clínico-Epidemiológico da Hanseníase em Nossa Senhora do Socorro. 2016. 79 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, São Cristóvão, 2016.https://ri.ufs.br/handle/riufs/3788Leprosy is a chronic, infectious and systemic disease caused by the bacillus Mycobacterium leprae, which can affect both genders, at all ages, leading to physical disabilities of several degrees. It is a worldwide sanitary problem and, in Brazil, is considered as endemic. The aim of this study was describe the clinical and epidemiological profiles of the disease, investigate the risk factors associated with the cases of leprosy, as well as analyze spatially the distribution of cases in the town of Nossa Senhora do Socorro. The study is observational and case-control. We considered as cases all the individuals diagnosed with leprosy who resided in the town and who were notified in the town´s Basic Heath Units and in Aracaju´s University Hospital and Center of Medical Specialties, in 2014. As control group, we considered individuals without diagnostic of the disease and who resided in the same house or in houses on the same street as the cases. For the data collection, we used the Inquiry on Risk Factors, the SINAN`s Leprosy Investigation/Notification Forms and the method of instantaneous positioning from a point collected by GPS. There was the analysis of the clinical and epidemiological variables, and the logistics regression described the association between the exposition variables and the leprosy cases. The average age found was 48.1±19 years and individuals were mostly male, brown-skinned and had multibacillary operational classification, with predominance of the Virchowian clinical form. We found a significant association between the presence of the current cases of leprosy in the town and the presence of other diseases in the individual, with infection through leprosy. Likewise, by analyzing schooling, family average income, presence of old cases of leprosy in the town and other diseases associated, a significant influence of such variables was observed upon the appearance of leprosy cases. The location of the leprosy cases showed heterogeneous spatial distribution in the town´s urban area. Also, four important clusters were observed in the region studied: two in the north and two in the south, highlighting the Marcos Freire II region. Socioeconomic factors may be associated with the leprosy cases in the town of Nossa Senhora do Socorro.A hanseníase é uma doença crônica, infecciosa, sistêmica, causada pelo bacilo, Mycobacterium leprae, que pode afetar ambos os sexos, em todas as idades, levando a incapacidades físicas de graus variados. É um problema sanitário mundial e, no Brasil, é considerada endêmica. O objetivo deste estudo foi descrever o perfil clínico e epidemiológico da hanseníase, investigar os fatores de risco associados as casos, bem como analisar espacialmente a distribuição dos casos no município de Nossa Senhora do Socorro. Trata-se de um estudo observacional, caso-controle. Foram considerados casos todos os indivíduos diagnosticados com hanseníase residentes no município, e, notificados nas UBS’s do mesmo, Hospital Universitário e Centro de Especialidades Médicas de Aracaju, no ano de 2014, e como grupo controle, indivíduos sem diagnóstico da doença e que residiam no mesmo domicílio ou em casas do mesmo logradouro de casos. Para a coleta dos dados, utilizou-se o Inquérito de Fatores de Risco, as Fichas de Notificação/Investigação da Hanseníase do SINAN, e o método de posicionamento instantâneo de um ponto coletado pelo GPS. Houve a análise das variáveis clínicas e epidemiológicas, e a regressão logística descreveu a associação entre as variáveis de exposição e os casos de hanseníase. A média de idade encontrada foi de 48,1±19 anos, eram, na maioria, do gênero masculino, pardos e possuíam classificação operacional multibacilar, com predomínio da forma clínica virchowiana. Uma associação significativa entre a presença de casos atuais de hanseníase no domicílio e a presença de outras doenças no indivíduo, com a infecção pela hanseníase, foi encontrada. Da mesma forma, analisando em conjunto, escolaridade, rendimento médio familiar, presença de casos antigos de hanseníase no domicílio e outras doenças associadas, verificou-se influência significativa dessas variáveis sobre o surgimento de casos de hanseníase. A localização dos casos de Hanseníase demonstrou distribuição espacial heterogênea na zona urbana do município e pôde-se observar quatro aglomerados importantes na região estudada, dois ao norte e dois ao sul, com destaque para a região do Marcos Freire II. Fatores socioeconômicos parecem estar associados ao aparecimento de casos de hanseníase no município de Nossa Senhora do Socorro.application/pdfporUniversidade Federal de SergipePós-Graduação em Ciências da SaúdeUFSBrasilCiências da saúdeHanseníaseEpidemiologiaAnálise espacialLeprosyEpidemiologySpatial analysisCIENCIAS DA SAUDEPerfil clínico-epidemiológico da Hanseníase em Nossa Senhora do SocorroEpidemiological and clinical profile of leprosy in Nossa Senhora do Socorro, Sergipe, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFSinstname:Universidade Federal de Sergipe (UFS)instacron:UFSTEXTMANUELA_ANDRADE_ALBUQUERQUE.pdf.txtMANUELA_ANDRADE_ALBUQUERQUE.pdf.txtExtracted texttext/plain121965https://ri.ufs.br/jspui/bitstream/riufs/3788/2/MANUELA_ANDRADE_ALBUQUERQUE.pdf.txt32198b3a03a90e11567e486578e08b51MD52THUMBNAILMANUELA_ANDRADE_ALBUQUERQUE.pdf.jpgMANUELA_ANDRADE_ALBUQUERQUE.pdf.jpgGenerated Thumbnailimage/jpeg1208https://ri.ufs.br/jspui/bitstream/riufs/3788/3/MANUELA_ANDRADE_ALBUQUERQUE.pdf.jpg6bf788433613dc0d18237af8b9abb964MD53ORIGINALMANUELA_ANDRADE_ALBUQUERQUE.pdfapplication/pdf1654604https://ri.ufs.br/jspui/bitstream/riufs/3788/1/MANUELA_ANDRADE_ALBUQUERQUE.pdf769aaa41a0a58572f2c5eefdc8e80043MD51riufs/37882017-11-28 16:48:42.662oai:oai:ri.ufs.br:repo_01:riufs/3788Repositório InstitucionalPUBhttps://ri.ufs.br/oai/requestrepositorio@academico.ufs.bropendoar:2017-11-28T19:48:42Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)false
dc.title.por.fl_str_mv Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
dc.title.alternative.eng.fl_str_mv Epidemiological and clinical profile of leprosy in Nossa Senhora do Socorro, Sergipe, Brazil
title Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
spellingShingle Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
Albuquerque, Manuela Andrade de
Ciências da saúde
Hanseníase
Epidemiologia
Análise espacial
Leprosy
Epidemiology
Spatial analysis
CIENCIAS DA SAUDE
title_short Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
title_full Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
title_fullStr Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
title_full_unstemmed Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
title_sort Perfil clínico-epidemiológico da Hanseníase em Nossa Senhora do Socorro
author Albuquerque, Manuela Andrade de
author_facet Albuquerque, Manuela Andrade de
author_role author
dc.contributor.author.fl_str_mv Albuquerque, Manuela Andrade de
dc.contributor.advisor1.fl_str_mv Araújo, Karina Conceição Gomes Machado de
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/3371277385797221
contributor_str_mv Araújo, Karina Conceição Gomes Machado de
dc.subject.por.fl_str_mv Ciências da saúde
Hanseníase
Epidemiologia
Análise espacial
topic Ciências da saúde
Hanseníase
Epidemiologia
Análise espacial
Leprosy
Epidemiology
Spatial analysis
CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv Leprosy
Epidemiology
Spatial analysis
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description Leprosy is a chronic, infectious and systemic disease caused by the bacillus Mycobacterium leprae, which can affect both genders, at all ages, leading to physical disabilities of several degrees. It is a worldwide sanitary problem and, in Brazil, is considered as endemic. The aim of this study was describe the clinical and epidemiological profiles of the disease, investigate the risk factors associated with the cases of leprosy, as well as analyze spatially the distribution of cases in the town of Nossa Senhora do Socorro. The study is observational and case-control. We considered as cases all the individuals diagnosed with leprosy who resided in the town and who were notified in the town´s Basic Heath Units and in Aracaju´s University Hospital and Center of Medical Specialties, in 2014. As control group, we considered individuals without diagnostic of the disease and who resided in the same house or in houses on the same street as the cases. For the data collection, we used the Inquiry on Risk Factors, the SINAN`s Leprosy Investigation/Notification Forms and the method of instantaneous positioning from a point collected by GPS. There was the analysis of the clinical and epidemiological variables, and the logistics regression described the association between the exposition variables and the leprosy cases. The average age found was 48.1±19 years and individuals were mostly male, brown-skinned and had multibacillary operational classification, with predominance of the Virchowian clinical form. We found a significant association between the presence of the current cases of leprosy in the town and the presence of other diseases in the individual, with infection through leprosy. Likewise, by analyzing schooling, family average income, presence of old cases of leprosy in the town and other diseases associated, a significant influence of such variables was observed upon the appearance of leprosy cases. The location of the leprosy cases showed heterogeneous spatial distribution in the town´s urban area. Also, four important clusters were observed in the region studied: two in the north and two in the south, highlighting the Marcos Freire II region. Socioeconomic factors may be associated with the leprosy cases in the town of Nossa Senhora do Socorro.
publishDate 2016
dc.date.issued.fl_str_mv 2016-02-26
dc.date.accessioned.fl_str_mv 2017-09-26T12:17:25Z
dc.date.available.fl_str_mv 2017-09-26T12:17:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv ALBUQUERQUE, Manuela Andrade de. Perfil Clínico-Epidemiológico da Hanseníase em Nossa Senhora do Socorro. 2016. 79 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, São Cristóvão, 2016.
dc.identifier.uri.fl_str_mv https://ri.ufs.br/handle/riufs/3788
identifier_str_mv ALBUQUERQUE, Manuela Andrade de. Perfil Clínico-Epidemiológico da Hanseníase em Nossa Senhora do Socorro. 2016. 79 f. Dissertação (Pós-Graduação em Ciências da Saúde) - Universidade Federal de Sergipe, São Cristóvão, 2016.
url https://ri.ufs.br/handle/riufs/3788
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Sergipe
dc.publisher.program.fl_str_mv Pós-Graduação em Ciências da Saúde
dc.publisher.initials.fl_str_mv UFS
dc.publisher.country.fl_str_mv Brasil
publisher.none.fl_str_mv Universidade Federal de Sergipe
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFS
instname:Universidade Federal de Sergipe (UFS)
instacron:UFS
instname_str Universidade Federal de Sergipe (UFS)
instacron_str UFS
institution UFS
reponame_str Repositório Institucional da UFS
collection Repositório Institucional da UFS
bitstream.url.fl_str_mv https://ri.ufs.br/jspui/bitstream/riufs/3788/2/MANUELA_ANDRADE_ALBUQUERQUE.pdf.txt
https://ri.ufs.br/jspui/bitstream/riufs/3788/3/MANUELA_ANDRADE_ALBUQUERQUE.pdf.jpg
https://ri.ufs.br/jspui/bitstream/riufs/3788/1/MANUELA_ANDRADE_ALBUQUERQUE.pdf
bitstream.checksum.fl_str_mv 32198b3a03a90e11567e486578e08b51
6bf788433613dc0d18237af8b9abb964
769aaa41a0a58572f2c5eefdc8e80043
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da UFS - Universidade Federal de Sergipe (UFS)
repository.mail.fl_str_mv repositorio@academico.ufs.br
_version_ 1851759364657905664