Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Barboza, Victor dos Santos lattes
Orientador(a): Pavanato, Maria Amália lattes
Banca de defesa: Vaucher, Rodrigo de Almeida lattes, Loreto, Érico Silva de lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Centro de Ciências da Saúde
Programa de Pós-Graduação: Programa de Pós-Graduação em Farmacologia
Departamento: Farmacologia
País: Brasil
Palavras-chave em Português:
Oomiceto
Óleos essenciais
Atividade antimicrobiana
Zoósporos
Palavras-chave em Inglês:
Oomycete
Antimicrobial activity
Zoospores
Essential oils
Área do conhecimento CNPq:
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
Link de acesso: http://repositorio.ufsm.br/handle/1/15071
Resumo: This study aimed to characterize the essential oils of Alpinia speciosa (EOAS), Eremanthus erythropappus (EOEE), Schinus lentiscifolius (EOSL), Hesperozygis ringens (EOHR) and Ocimum americanum (EOOA), and to investigate the in vitro antimicrobial activity against Saprolegnia parasitica zoospores (strain CBS 223.65). Composition of the oils was analyzed by gas chromatography/mass spectrometry (GC/MS) using flame ionization detector for GC. Evaluation of the antimicrobial activity was performed through an adaptation of the method according to the CLSI M38-A2. The main chemical compounds identified were: eucalyptol (30.58%) and terpinen-4-ol (20.04%) in EOAS; α-bisabolol (71.47%) in EOEE; 3-carene (55.51%) and α-thujene (11.03%) in EOSL; pulegone (88.31%) in EOHR; and linalol (28.96%), eucalyptol (17.83%) and eugenol (16.22%) in EOOA. The minimum inhibitory concentration was >300 μg/mL for EOAS, EOHR and EOOA; 320 μg/mL for EOEE; and 160 μg/mL for EOSL. Evaluation of the minimum oomyceticidal concentration identified values of >320 μg/mL for EOAS, EOEE, EOHR and EOOA, while 300 μg/mL was found as the lowest lethal concentration of EOSL against Saprolegnia parasitica. The present findings indicate the susceptibility of Saprolegnia parasitica CBS 223.65 to the tested essential oils. This is the first report on the antioomycotic property of EOAS, EOEE, EOSL, EOHR and EOOA against Saprolegnia parasitica CBS 223.65, indicating that this class of natural products could be a feasible alternative for preventing and/or treating Saprolegnia parasitica caused saprolegniosis. Nonetheless, further studies are required in order to assess the in vivo antioomycotic activity.
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spelling 2018-12-11T13:22:37Z2018-12-11T13:22:37Z2018-05-29http://repositorio.ufsm.br/handle/1/15071This study aimed to characterize the essential oils of Alpinia speciosa (EOAS), Eremanthus erythropappus (EOEE), Schinus lentiscifolius (EOSL), Hesperozygis ringens (EOHR) and Ocimum americanum (EOOA), and to investigate the in vitro antimicrobial activity against Saprolegnia parasitica zoospores (strain CBS 223.65). Composition of the oils was analyzed by gas chromatography/mass spectrometry (GC/MS) using flame ionization detector for GC. Evaluation of the antimicrobial activity was performed through an adaptation of the method according to the CLSI M38-A2. The main chemical compounds identified were: eucalyptol (30.58%) and terpinen-4-ol (20.04%) in EOAS; α-bisabolol (71.47%) in EOEE; 3-carene (55.51%) and α-thujene (11.03%) in EOSL; pulegone (88.31%) in EOHR; and linalol (28.96%), eucalyptol (17.83%) and eugenol (16.22%) in EOOA. The minimum inhibitory concentration was >300 μg/mL for EOAS, EOHR and EOOA; 320 μg/mL for EOEE; and 160 μg/mL for EOSL. Evaluation of the minimum oomyceticidal concentration identified values of >320 μg/mL for EOAS, EOEE, EOHR and EOOA, while 300 μg/mL was found as the lowest lethal concentration of EOSL against Saprolegnia parasitica. The present findings indicate the susceptibility of Saprolegnia parasitica CBS 223.65 to the tested essential oils. This is the first report on the antioomycotic property of EOAS, EOEE, EOSL, EOHR and EOOA against Saprolegnia parasitica CBS 223.65, indicating that this class of natural products could be a feasible alternative for preventing and/or treating Saprolegnia parasitica caused saprolegniosis. Nonetheless, further studies are required in order to assess the in vivo antioomycotic activity.Objetivou-se caracterizar os óleos essenciais de Alpinia speciosa (EOAS), Eremanthus erythropappus (EOEE), Schinus lentiscifolius (EOSL), Hesperozygis ringens (EOHR) e Ocimum americanum (EOOA), e investigar a atividade antimicrobiana in vitro contra Saprolegnia parasitica. zoósporos (estirpe CBS 223.65). A composição dos óleos foi analisada por cromatografia gasosa / espectrometria de massa (CG /MS) utilizando detector de ionização de chama para CG. A avaliação da atividade antimicrobiana foi realizada por meio de uma adaptação do método do CLSI M38-A2. Os principais compostos químicos identificados foram: eucaliptol (30,58%) e terpinen-4-ol (20,04%) em EOAS; α-bisabolol (71,47%) em EOEE; 3-careno (55,51%) e α-thujone (11,03%) em EOSL; pulegona (88,31%) em EOHR; e linalol (28,96%), eucaliptol (17,83%) e eugenol (16,22%) na EOOA. A concentração inibitória mínima foi> 300 μg / mL para EOAS, EOHR e EOOA; 320 μg/mL para EOEE; e 160 μg/mL para EOSL. A avaliação da concentração mínima oomiceticidal identificou valores> 320 μg/mL para EOAS, EOEE, EOHR e EOOA, enquanto 300 μg/mL foi a menor concentração letal de EOSL contra Saprolegnia parasitica. Os presentes resultados indicam a suscetibilidade de Saprolegnia parasitica CBS 223.65 aos óleos essenciais testados. Este é o primeiro relato da propriedade antioomicótica de EOAS, EOEE, EOSL, EOHR e EOOA contra Saprolegnia parasitica CBS 223.65, indicando que esta classe de produtos naturais poderia ser uma alternativa viável para prevenir e/ou tratar a saprolegniose causada pela Saprolegnia parasitica. No entanto, mais estudos são necessários para avaliar a atividade antioomiceto in vivo.porUniversidade Federal de Santa MariaCentro de Ciências da SaúdePrograma de Pós-Graduação em FarmacologiaUFSMBrasilFarmacologiaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessOomicetoÓleos essenciaisAtividade antimicrobianaZoósporosOomyceteAntimicrobial activityZoosporesEssential oilsCNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIACaracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasiticaCharacterization and investigation of the antioomycete activity of essential oils of Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens and Ocimum americanum against Saprolegnia parasiticainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPavanato, Maria Amáliahttp://lattes.cnpq.br/8701892865724171Vaucher, Rodrigo de Almeidahttp://lattes.cnpq.br/0953074420467371Loreto, Érico Silva dehttp://lattes.cnpq.br/5475233864057995http://lattes.cnpq.br/1357680906879171Barboza, Victor dos Santos2010000000006007d7838b4-f884-4ada-a8a9-eb44cdaac1be92ba9b8c-8ca1-4c22-b071-92ab458842870e05a3fd-0c5a-4378-b8bd-c94f3ba18552ea251119-5531-432f-bf54-8c8111248727reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALDIS_PPGFARMACOLOGIA_2018_BARBOZA_VICTOR.pdfDIS_PPGFARMACOLOGIA_2018_BARBOZA_VICTOR.pdfDissertação de Mestradoapplication/pdf764415http://repositorio.ufsm.br/bitstream/1/15071/1/DIS_PPGFARMACOLOGIA_2018_BARBOZA_VICTOR.pdfae100f3311578a1e9c08a485203a984bMD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; 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dc.title.por.fl_str_mv Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
dc.title.alternative.eng.fl_str_mv Characterization and investigation of the antioomycete activity of essential oils of Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens and Ocimum americanum against Saprolegnia parasitica
title Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
spellingShingle Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
Barboza, Victor dos Santos
Oomiceto
Óleos essenciais
Atividade antimicrobiana
Zoósporos
Oomycete
Antimicrobial activity
Zoospores
Essential oils
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
title_short Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
title_full Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
title_fullStr Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
title_full_unstemmed Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
title_sort Caracterização e investigação da atividade anti-oomiceto de óleos essenciais de Alpinia speciosa, Eremanthus erythropappus, Schinus lentiscifolius, Hesperozygis ringens e Ocimum americanum frente à Saprolegnia parasitica
author Barboza, Victor dos Santos
author_facet Barboza, Victor dos Santos
author_role author
dc.contributor.advisor1.fl_str_mv Pavanato, Maria Amália
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/8701892865724171
dc.contributor.referee1.fl_str_mv Vaucher, Rodrigo de Almeida
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/0953074420467371
dc.contributor.referee2.fl_str_mv Loreto, Érico Silva de
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/5475233864057995
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/1357680906879171
dc.contributor.author.fl_str_mv Barboza, Victor dos Santos
contributor_str_mv Pavanato, Maria Amália
Vaucher, Rodrigo de Almeida
Loreto, Érico Silva de
dc.subject.por.fl_str_mv Oomiceto
Óleos essenciais
Atividade antimicrobiana
Zoósporos
topic Oomiceto
Óleos essenciais
Atividade antimicrobiana
Zoósporos
Oomycete
Antimicrobial activity
Zoospores
Essential oils
CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
dc.subject.eng.fl_str_mv Oomycete
Antimicrobial activity
Zoospores
Essential oils
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS BIOLOGICAS::FARMACOLOGIA
description This study aimed to characterize the essential oils of Alpinia speciosa (EOAS), Eremanthus erythropappus (EOEE), Schinus lentiscifolius (EOSL), Hesperozygis ringens (EOHR) and Ocimum americanum (EOOA), and to investigate the in vitro antimicrobial activity against Saprolegnia parasitica zoospores (strain CBS 223.65). Composition of the oils was analyzed by gas chromatography/mass spectrometry (GC/MS) using flame ionization detector for GC. Evaluation of the antimicrobial activity was performed through an adaptation of the method according to the CLSI M38-A2. The main chemical compounds identified were: eucalyptol (30.58%) and terpinen-4-ol (20.04%) in EOAS; α-bisabolol (71.47%) in EOEE; 3-carene (55.51%) and α-thujene (11.03%) in EOSL; pulegone (88.31%) in EOHR; and linalol (28.96%), eucalyptol (17.83%) and eugenol (16.22%) in EOOA. The minimum inhibitory concentration was >300 μg/mL for EOAS, EOHR and EOOA; 320 μg/mL for EOEE; and 160 μg/mL for EOSL. Evaluation of the minimum oomyceticidal concentration identified values of >320 μg/mL for EOAS, EOEE, EOHR and EOOA, while 300 μg/mL was found as the lowest lethal concentration of EOSL against Saprolegnia parasitica. The present findings indicate the susceptibility of Saprolegnia parasitica CBS 223.65 to the tested essential oils. This is the first report on the antioomycotic property of EOAS, EOEE, EOSL, EOHR and EOOA against Saprolegnia parasitica CBS 223.65, indicating that this class of natural products could be a feasible alternative for preventing and/or treating Saprolegnia parasitica caused saprolegniosis. Nonetheless, further studies are required in order to assess the in vivo antioomycotic activity.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-12-11T13:22:37Z
dc.date.available.fl_str_mv 2018-12-11T13:22:37Z
dc.date.issued.fl_str_mv 2018-05-29
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
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dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/15071
url http://repositorio.ufsm.br/handle/1/15071
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language por
dc.relation.cnpq.fl_str_mv 201000000000
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dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Farmacologia
dc.publisher.initials.fl_str_mv UFSM
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Farmacologia
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
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