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Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica

Detalhes bibliográficos
Ano de defesa: 2019
Autor(a) principal: Sarturi, Vanessa Zanchi
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
dARK ID: ark:/26339/0013000001d8n
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://repositorio.ufsm.br/handle/1/19627
Resumo: Videolaparoscopy has evolved and gained prominence in veterinary medicine, both for the technological advance, more technical training of the surgeons, preference of the tutors, and for the advantages presented to the animals when compared to the conventional techniques. However, the anesthesia for these patients must be differentiated, since there is a need to create a workspace by the institution of pneumoperitoneum with medical carbon dioxide. The objectives of this study were to evaluate the hemodynamic effects produced by continuous infusion of propofol alone and associated with ketamine, ketamine s + or remifentanil in young bitches submitted to videolaparoscopic ovariectomy. Total intravenous anesthesia is a modality in which administration of drugs for induction and maintenance is performed exclusively via intravenous (TIVA). Thirty-two healthy bitches, with average weight between 18 and 24 kg and 6 to 24 months of age were included. They also received pre-anesthetic medication with acepromazine 0.2 mg / kg and meperidine 4mg / kg intramuscularly and induction with propofol 4mg / kg. The animals were divided into four groups of eight animals each receiving intravenous anesthetic maintenance according to their protocol: G1 propofol 0.6mg / kg / min, G2 propofol 0.4mg / kg / min. associated with ketamine 100ug / kg / min., G3 propofol 0.4mg / kg / min. associated with ketamine s + 50ug / kg / min., G4 propofol 0.4mg / kg / min. associated with remifentanil at a dose of 0.2ug / kg / min. All groups received the infusion over 90 minutes. The parameters evaluated were: heart rate, systolic, diastolic and mean arterial pressure, cardiac output, partial oxygen saturation, expired concentration of carbon dioxide, rectal temperature and glycemia. All animals were submitted to a minimally invasive technique by the same surgical team. After analyzing the results, there was no statistical interaction (P> 0.05) between groups and moments of the study. It is concluded that TIVA and its associations have demonstrated satisfactory results, acceptable hemodynamic stability and trans-operative analgesia for laparoscopic ovariectomy in young bitches. However, it is noteworthy that the use of propofol alone was not sufficient for anesthetic maintenance. necessary analgesic supplementation for the animals of this group, and also confirmed the need for the institution of controlled ventilation to the protocols tested.
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spelling Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópicaIntravenous anesthesia with propofol associated with different drugs in bitches submitted to videolaparoscopic ovariectomyCastraçãoPequenos animaisAnestesia geralVideocirurgiaCastrationSmall animalsGeneral anesthesiaVideo surgeryCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAVideolaparoscopy has evolved and gained prominence in veterinary medicine, both for the technological advance, more technical training of the surgeons, preference of the tutors, and for the advantages presented to the animals when compared to the conventional techniques. However, the anesthesia for these patients must be differentiated, since there is a need to create a workspace by the institution of pneumoperitoneum with medical carbon dioxide. The objectives of this study were to evaluate the hemodynamic effects produced by continuous infusion of propofol alone and associated with ketamine, ketamine s + or remifentanil in young bitches submitted to videolaparoscopic ovariectomy. Total intravenous anesthesia is a modality in which administration of drugs for induction and maintenance is performed exclusively via intravenous (TIVA). Thirty-two healthy bitches, with average weight between 18 and 24 kg and 6 to 24 months of age were included. They also received pre-anesthetic medication with acepromazine 0.2 mg / kg and meperidine 4mg / kg intramuscularly and induction with propofol 4mg / kg. The animals were divided into four groups of eight animals each receiving intravenous anesthetic maintenance according to their protocol: G1 propofol 0.6mg / kg / min, G2 propofol 0.4mg / kg / min. associated with ketamine 100ug / kg / min., G3 propofol 0.4mg / kg / min. associated with ketamine s + 50ug / kg / min., G4 propofol 0.4mg / kg / min. associated with remifentanil at a dose of 0.2ug / kg / min. All groups received the infusion over 90 minutes. The parameters evaluated were: heart rate, systolic, diastolic and mean arterial pressure, cardiac output, partial oxygen saturation, expired concentration of carbon dioxide, rectal temperature and glycemia. All animals were submitted to a minimally invasive technique by the same surgical team. After analyzing the results, there was no statistical interaction (P> 0.05) between groups and moments of the study. It is concluded that TIVA and its associations have demonstrated satisfactory results, acceptable hemodynamic stability and trans-operative analgesia for laparoscopic ovariectomy in young bitches. However, it is noteworthy that the use of propofol alone was not sufficient for anesthetic maintenance. necessary analgesic supplementation for the animals of this group, and also confirmed the need for the institution of controlled ventilation to the protocols tested.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESA videolaparoscopia tem evoluído e ganhado destaque na medicina veterinária, tanto pelo avanço tecnológico, maior capacitação técnica dos cirurgiões, preferência dos tutores, quanto pelas vantagens apresentadas aos animais quando comparadas às técnicas convencionais. Porém a anestesia para estes pacientes deve ser diferenciada, pois há necessidade de criação de um espaço de trabalho pela instituição do pneumoperitônio com gás carbônico medicinal. Os objetivos desse estudo foram avaliar os efeitos hemodinâmicos produzidos pela infusão contínua de propofol isolado e associado a cetamina, cetamina S+ ou remifentanil em cadelas jovens submetidas a ovariectomia videolaparoscópica. Foram incluídas 32 cadelas hígidas, com peso médio entre 18 e 24 kg e com 6 a 24 meses de idade. Receberam medicação pré-anestésica com acepromazina (0,1 mg/kg) e meperidina (4mg/kg) intramuscular e indução com propofol (4mg/kg). Os animais foram distruibuidos em quatro grupos de oito animais cada, os quais receberam diferentes protocolos para manutenção da anestesia: G1 propofol (0,6mg/kg/min), G2 propofol (0,4 mg/kg/min) associado a cetamina (100ug/kg/min), G3 propofol (0,4mg/kg/min) associado a cetamina S+ (50ug/kg/min), G4 propofol (0,4 mg/kg/min) associado ao remifentanil na dose de (0,2ug/kg/min). Todos os grupos receberam a infusão durante 90 minutos. Os parâmetros avaliados foram: frequência cardíaca, pressão arterial sistólica, diastólica e média, débito cardíaco, saturação parcial de oxigênio nas hemoglobinas circulantes, concentração de dióxido de carbono ao final da expiração, temperatura retal e glicemia. Todos os animais foram submetidos a técnica minimamente invasiva pela mesma equipe cirúrgica. Após análise dos resultados, não houve interação estatística (p>0,05) entre grupos em cada momento. Conclui-se que os protocolos de TIVA testados demonstraram resultados satisfatórios, estabilidade hemodinâmica e analgesia trans-operatória aceitáveis para a realização de ovariectomia videolaparoscópica em cadelas jovens, contudo ressalta-se que o uso isolado do propofol não foi suficiente para a manutenção anestésica, sendo necessária complementação analgésica para os animais deste grupo, e ainda confirma-se a necessidade de instituição de ventilação controlada aos protocolos testados.Universidade Federal de Santa MariaBrasilMedicina VeterináriaUFSMPrograma de Pós-Graduação em Medicina VeterináriaCentro de Ciências RuraisBrun, Maurício Velosohttp://lattes.cnpq.br/3913050752928325Krause, Alexandrehttp://lattes.cnpq.br/7760558908777387Oliveira, Marília Teresa dehttp://lattes.cnpq.br/8345134253755342Müller, Daniel Curvello de Mendonçahttp://lattes.cnpq.br/9457849435452537Beck, Carlos Afonso de Castrohttp://lattes.cnpq.br/9258606189481470Sarturi, Vanessa Zanchi2020-02-19T15:48:54Z2020-02-19T15:48:54Z2019-08-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/19627ark:/26339/0013000001d8nporAttribution-NonCommercial-NoDerivatives 4.0 Internationalinfo:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2020-02-20T06:02:50Zoai:repositorio.ufsm.br:1/19627Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/PUBhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.com||manancial@ufsm.bropendoar:2020-02-20T06:02:50Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
Intravenous anesthesia with propofol associated with different drugs in bitches submitted to videolaparoscopic ovariectomy
title Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
spellingShingle Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
Sarturi, Vanessa Zanchi
Castração
Pequenos animais
Anestesia geral
Videocirurgia
Castration
Small animals
General anesthesia
Video surgery
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
title_full Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
title_fullStr Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
title_full_unstemmed Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
title_sort Anestesia intravenosa total com propofol associado a diferentes fármacos em cadelas submetidas à ovariectomia videolaparoscópica
author Sarturi, Vanessa Zanchi
author_facet Sarturi, Vanessa Zanchi
author_role author
dc.contributor.none.fl_str_mv Brun, Maurício Veloso
http://lattes.cnpq.br/3913050752928325
Krause, Alexandre
http://lattes.cnpq.br/7760558908777387
Oliveira, Marília Teresa de
http://lattes.cnpq.br/8345134253755342
Müller, Daniel Curvello de Mendonça
http://lattes.cnpq.br/9457849435452537
Beck, Carlos Afonso de Castro
http://lattes.cnpq.br/9258606189481470
dc.contributor.author.fl_str_mv Sarturi, Vanessa Zanchi
dc.subject.por.fl_str_mv Castração
Pequenos animais
Anestesia geral
Videocirurgia
Castration
Small animals
General anesthesia
Video surgery
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
topic Castração
Pequenos animais
Anestesia geral
Videocirurgia
Castration
Small animals
General anesthesia
Video surgery
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Videolaparoscopy has evolved and gained prominence in veterinary medicine, both for the technological advance, more technical training of the surgeons, preference of the tutors, and for the advantages presented to the animals when compared to the conventional techniques. However, the anesthesia for these patients must be differentiated, since there is a need to create a workspace by the institution of pneumoperitoneum with medical carbon dioxide. The objectives of this study were to evaluate the hemodynamic effects produced by continuous infusion of propofol alone and associated with ketamine, ketamine s + or remifentanil in young bitches submitted to videolaparoscopic ovariectomy. Total intravenous anesthesia is a modality in which administration of drugs for induction and maintenance is performed exclusively via intravenous (TIVA). Thirty-two healthy bitches, with average weight between 18 and 24 kg and 6 to 24 months of age were included. They also received pre-anesthetic medication with acepromazine 0.2 mg / kg and meperidine 4mg / kg intramuscularly and induction with propofol 4mg / kg. The animals were divided into four groups of eight animals each receiving intravenous anesthetic maintenance according to their protocol: G1 propofol 0.6mg / kg / min, G2 propofol 0.4mg / kg / min. associated with ketamine 100ug / kg / min., G3 propofol 0.4mg / kg / min. associated with ketamine s + 50ug / kg / min., G4 propofol 0.4mg / kg / min. associated with remifentanil at a dose of 0.2ug / kg / min. All groups received the infusion over 90 minutes. The parameters evaluated were: heart rate, systolic, diastolic and mean arterial pressure, cardiac output, partial oxygen saturation, expired concentration of carbon dioxide, rectal temperature and glycemia. All animals were submitted to a minimally invasive technique by the same surgical team. After analyzing the results, there was no statistical interaction (P> 0.05) between groups and moments of the study. It is concluded that TIVA and its associations have demonstrated satisfactory results, acceptable hemodynamic stability and trans-operative analgesia for laparoscopic ovariectomy in young bitches. However, it is noteworthy that the use of propofol alone was not sufficient for anesthetic maintenance. necessary analgesic supplementation for the animals of this group, and also confirmed the need for the institution of controlled ventilation to the protocols tested.
publishDate 2019
dc.date.none.fl_str_mv 2019-08-05
2020-02-19T15:48:54Z
2020-02-19T15:48:54Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/doctoralThesis
format doctoralThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/19627
dc.identifier.dark.fl_str_mv ark:/26339/0013000001d8n
url http://repositorio.ufsm.br/handle/1/19627
identifier_str_mv ark:/26339/0013000001d8n
dc.language.iso.fl_str_mv por
language por
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Medicina Veterinária
UFSM
Programa de Pós-Graduação em Medicina Veterinária
Centro de Ciências Rurais
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com||manancial@ufsm.br
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