Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
Ano de defesa: | 2016 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Federal de Santa Maria
Centro de Ciências da Saúde |
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Farmacologia
|
Departamento: |
Farmacologia
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://repositorio.ufsm.br/handle/1/18003 |
Resumo: | Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures. |
id |
UFSM_d22809c34012af98466826e68c37b062 |
---|---|
oai_identifier_str |
oai:repositorio.ufsm.br:1/18003 |
network_acronym_str |
UFSM |
network_name_str |
Biblioteca Digital de Teses e Dissertações do UFSM |
repository_id_str |
|
spelling |
2019-08-23T18:30:26Z2019-08-23T18:30:26Z2016-03-02http://repositorio.ufsm.br/handle/1/18003Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures.Introdução: Osteoporose é uma doença que cursa com maior fragilidade óssea e aumento do risco de fraturas, levando a sérios agravos físicos, psicossociais e econômicos. Por isso, estratégias para diagnosticar precocemente os pacientes com alto risco para fraturas têm sido recomendadas com a finalidade de instituir tratamento. Entretanto, apesar da disponibilidade de fármacos efetivos para a prevenção de fraturas ósseas, observa-se uma baixa aderência aos mesmos. Objetivo: avaliar o papel de alguns fatores que poderiam estar associados ao tratamento da osteoporose em mulheres na pós-menopausa. Metodologia: Tratou-se de um estudo transversal analítico, realizado no período de 01 de março a 31 de agosto de 2013, no qual foram incluídas 1025 mulheres com idade igual ou acima de 55 anos, na pós-menopausa e que frequentassem Unidades Básicas de Saúde no município de Santa Maria, RS. Mulheres com dificuldades de comunicação e mulheres que ainda estivessem menstruando foram excluídas. As informações foram obtidas por meio de aplicação de um questionário padronizado. Foram consideradas mulheres em tratamento as que estivessem utilizando pelo menos um dos seguintes fármacos: alendronato, risedronato, pamidronato, acido zoledrônico, raloxifeno, estrógeno, calcitonina, teriparatida ou ranelato de estrôncio no momento da aplicação do questionário. Foram consideradas mulheres com tratamento no passado as mulheres que tomaram algum dos medicamentos descritos acima em período anterior ao estudo. Resultados: Das 1025 mulheres, 82 (8%) estavam utilizando algum tipo de tratamento para a osteoporose, 59 (5,7%) trataram no passado e 884 (86,3%) nunca trataram. Os fatores independentemente associados ao tratamento foram a realização de Densitometria Óssea, ter o diagnóstico de osteoporose pela Densitometria Óssea e ter recebido informação sobre osteoporose. Conclusão: Os resultados sugerem que informar adequadamente as pacientes durante a consulta clínica e a popularização da Densitometria Óssea podem ter um impacto positivo na adesão ao tratamento da osteoporose e prevenção de fraturas primárias e secundárias.porUniversidade Federal de Santa MariaCentro de Ciências da SaúdePrograma de Pós-Graduação em FarmacologiaUFSMBrasilFarmacologiaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessOsteoporosePós-menopausaTratamentoAderênciaDensitometria ósseaInformaçãoOsteoporosisPost-menopauseTreatmentAdherenceBone densitometryInformationCNPQ::CIENCIAS DA SAUDE::FARMACIAFatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausaFactors influencing the treatment of osteoporosis in postmenopausal womeninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPremaor, Melissa Orlandinhttp://lattes.cnpq.br/1919693261808995Comim, Fabio Vasconcelloshttp://lattes.cnpq.br/5119233991388822Moresco, Rafael Noalhttp://lattes.cnpq.br/2269922709577261Gomes, Patríciahttp://lattes.cnpq.br/7622203730579234http://lattes.cnpq.br/7553265208772531Montagner, Lia Mara Zamberlan400300000005600ac7b8248-d4ca-4014-81f1-9c9db5a4eabdf9e59491-b644-45ef-8ba3-6f9a29f72e863ffbe810-4010-4acb-b64f-571aa21e74e505b536c5-19fb-4cae-9d69-46730a16ed09ef9eef3d-25fd-4747-ae4d-5fed54a703b1reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdfDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdfDissertação de Mestradoapplication/pdf1180185http://repositorio.ufsm.br/bitstream/1/18003/1/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf1e8f3eeab68c077625e2b4bafad6c077MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.ufsm.br/bitstream/1/18003/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81956http://repositorio.ufsm.br/bitstream/1/18003/3/license.txt2f0571ecee68693bd5cd3f17c1e075dfMD53TEXTDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txtDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txtExtracted texttext/plain80677http://repositorio.ufsm.br/bitstream/1/18003/4/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txt3da333c768373c40a79d1e07aa9f5152MD54THUMBNAILDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpgDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpgIM Thumbnailimage/jpeg4433http://repositorio.ufsm.br/bitstream/1/18003/5/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpg8237f7c90756b140b3e0631367a8c00bMD551/180032019-08-24 03:01:29.312oai:repositorio.ufsm.br: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 Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2019-08-24T06:01:29Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)false |
dc.title.por.fl_str_mv |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
dc.title.alternative.eng.fl_str_mv |
Factors influencing the treatment of osteoporosis in postmenopausal women |
title |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
spellingShingle |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa Montagner, Lia Mara Zamberlan Osteoporose Pós-menopausa Tratamento Aderência Densitometria óssea Informação Osteoporosis Post-menopause Treatment Adherence Bone densitometry Information CNPQ::CIENCIAS DA SAUDE::FARMACIA |
title_short |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
title_full |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
title_fullStr |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
title_full_unstemmed |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
title_sort |
Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa |
author |
Montagner, Lia Mara Zamberlan |
author_facet |
Montagner, Lia Mara Zamberlan |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Premaor, Melissa Orlandin |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/1919693261808995 |
dc.contributor.advisor-co1.fl_str_mv |
Comim, Fabio Vasconcellos |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/5119233991388822 |
dc.contributor.referee1.fl_str_mv |
Moresco, Rafael Noal |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/2269922709577261 |
dc.contributor.referee2.fl_str_mv |
Gomes, Patrícia |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/7622203730579234 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/7553265208772531 |
dc.contributor.author.fl_str_mv |
Montagner, Lia Mara Zamberlan |
contributor_str_mv |
Premaor, Melissa Orlandin Comim, Fabio Vasconcellos Moresco, Rafael Noal Gomes, Patrícia |
dc.subject.por.fl_str_mv |
Osteoporose Pós-menopausa Tratamento Aderência Densitometria óssea Informação |
topic |
Osteoporose Pós-menopausa Tratamento Aderência Densitometria óssea Informação Osteoporosis Post-menopause Treatment Adherence Bone densitometry Information CNPQ::CIENCIAS DA SAUDE::FARMACIA |
dc.subject.eng.fl_str_mv |
Osteoporosis Post-menopause Treatment Adherence Bone densitometry Information |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS DA SAUDE::FARMACIA |
description |
Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures. |
publishDate |
2016 |
dc.date.issued.fl_str_mv |
2016-03-02 |
dc.date.accessioned.fl_str_mv |
2019-08-23T18:30:26Z |
dc.date.available.fl_str_mv |
2019-08-23T18:30:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://repositorio.ufsm.br/handle/1/18003 |
url |
http://repositorio.ufsm.br/handle/1/18003 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.cnpq.fl_str_mv |
400300000005 |
dc.relation.confidence.fl_str_mv |
600 |
dc.relation.authority.fl_str_mv |
ac7b8248-d4ca-4014-81f1-9c9db5a4eabd f9e59491-b644-45ef-8ba3-6f9a29f72e86 3ffbe810-4010-4acb-b64f-571aa21e74e5 05b536c5-19fb-4cae-9d69-46730a16ed09 ef9eef3d-25fd-4747-ae4d-5fed54a703b1 |
dc.rights.driver.fl_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Centro de Ciências da Saúde |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Farmacologia |
dc.publisher.initials.fl_str_mv |
UFSM |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Farmacologia |
publisher.none.fl_str_mv |
Universidade Federal de Santa Maria Centro de Ciências da Saúde |
dc.source.none.fl_str_mv |
reponame:Biblioteca Digital de Teses e Dissertações do UFSM instname:Universidade Federal de Santa Maria (UFSM) instacron:UFSM |
instname_str |
Universidade Federal de Santa Maria (UFSM) |
instacron_str |
UFSM |
institution |
UFSM |
reponame_str |
Biblioteca Digital de Teses e Dissertações do UFSM |
collection |
Biblioteca Digital de Teses e Dissertações do UFSM |
bitstream.url.fl_str_mv |
http://repositorio.ufsm.br/bitstream/1/18003/1/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf http://repositorio.ufsm.br/bitstream/1/18003/2/license_rdf http://repositorio.ufsm.br/bitstream/1/18003/3/license.txt http://repositorio.ufsm.br/bitstream/1/18003/4/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txt http://repositorio.ufsm.br/bitstream/1/18003/5/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpg |
bitstream.checksum.fl_str_mv |
1e8f3eeab68c077625e2b4bafad6c077 4460e5956bc1d1639be9ae6146a50347 2f0571ecee68693bd5cd3f17c1e075df 3da333c768373c40a79d1e07aa9f5152 8237f7c90756b140b3e0631367a8c00b |
bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM) |
repository.mail.fl_str_mv |
atendimento.sib@ufsm.br||tedebc@gmail.com |
_version_ |
1801485460360396800 |