Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa

Detalhes bibliográficos
Ano de defesa: 2016
Autor(a) principal: Montagner, Lia Mara Zamberlan lattes
Orientador(a): Premaor, Melissa Orlandin lattes
Banca de defesa: Moresco, Rafael Noal lattes, Gomes, Patrícia lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Centro de Ciências da Saúde
Programa de Pós-Graduação: Programa de Pós-Graduação em Farmacologia
Departamento: Farmacologia
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://repositorio.ufsm.br/handle/1/18003
Resumo: Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures.
id UFSM_d22809c34012af98466826e68c37b062
oai_identifier_str oai:repositorio.ufsm.br:1/18003
network_acronym_str UFSM
network_name_str Biblioteca Digital de Teses e Dissertações do UFSM
repository_id_str
spelling 2019-08-23T18:30:26Z2019-08-23T18:30:26Z2016-03-02http://repositorio.ufsm.br/handle/1/18003Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures.Introdução: Osteoporose é uma doença que cursa com maior fragilidade óssea e aumento do risco de fraturas, levando a sérios agravos físicos, psicossociais e econômicos. Por isso, estratégias para diagnosticar precocemente os pacientes com alto risco para fraturas têm sido recomendadas com a finalidade de instituir tratamento. Entretanto, apesar da disponibilidade de fármacos efetivos para a prevenção de fraturas ósseas, observa-se uma baixa aderência aos mesmos. Objetivo: avaliar o papel de alguns fatores que poderiam estar associados ao tratamento da osteoporose em mulheres na pós-menopausa. Metodologia: Tratou-se de um estudo transversal analítico, realizado no período de 01 de março a 31 de agosto de 2013, no qual foram incluídas 1025 mulheres com idade igual ou acima de 55 anos, na pós-menopausa e que frequentassem Unidades Básicas de Saúde no município de Santa Maria, RS. Mulheres com dificuldades de comunicação e mulheres que ainda estivessem menstruando foram excluídas. As informações foram obtidas por meio de aplicação de um questionário padronizado. Foram consideradas mulheres em tratamento as que estivessem utilizando pelo menos um dos seguintes fármacos: alendronato, risedronato, pamidronato, acido zoledrônico, raloxifeno, estrógeno, calcitonina, teriparatida ou ranelato de estrôncio no momento da aplicação do questionário. Foram consideradas mulheres com tratamento no passado as mulheres que tomaram algum dos medicamentos descritos acima em período anterior ao estudo. Resultados: Das 1025 mulheres, 82 (8%) estavam utilizando algum tipo de tratamento para a osteoporose, 59 (5,7%) trataram no passado e 884 (86,3%) nunca trataram. Os fatores independentemente associados ao tratamento foram a realização de Densitometria Óssea, ter o diagnóstico de osteoporose pela Densitometria Óssea e ter recebido informação sobre osteoporose. Conclusão: Os resultados sugerem que informar adequadamente as pacientes durante a consulta clínica e a popularização da Densitometria Óssea podem ter um impacto positivo na adesão ao tratamento da osteoporose e prevenção de fraturas primárias e secundárias.porUniversidade Federal de Santa MariaCentro de Ciências da SaúdePrograma de Pós-Graduação em FarmacologiaUFSMBrasilFarmacologiaAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessOsteoporosePós-menopausaTratamentoAderênciaDensitometria ósseaInformaçãoOsteoporosisPost-menopauseTreatmentAdherenceBone densitometryInformationCNPQ::CIENCIAS DA SAUDE::FARMACIAFatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausaFactors influencing the treatment of osteoporosis in postmenopausal womeninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisPremaor, Melissa Orlandinhttp://lattes.cnpq.br/1919693261808995Comim, Fabio Vasconcelloshttp://lattes.cnpq.br/5119233991388822Moresco, Rafael Noalhttp://lattes.cnpq.br/2269922709577261Gomes, Patríciahttp://lattes.cnpq.br/7622203730579234http://lattes.cnpq.br/7553265208772531Montagner, Lia Mara Zamberlan400300000005600ac7b8248-d4ca-4014-81f1-9c9db5a4eabdf9e59491-b644-45ef-8ba3-6f9a29f72e863ffbe810-4010-4acb-b64f-571aa21e74e505b536c5-19fb-4cae-9d69-46730a16ed09ef9eef3d-25fd-4747-ae4d-5fed54a703b1reponame:Biblioteca Digital de Teses e Dissertações do UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSMORIGINALDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdfDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdfDissertação de Mestradoapplication/pdf1180185http://repositorio.ufsm.br/bitstream/1/18003/1/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf1e8f3eeab68c077625e2b4bafad6c077MD51CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805http://repositorio.ufsm.br/bitstream/1/18003/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-81956http://repositorio.ufsm.br/bitstream/1/18003/3/license.txt2f0571ecee68693bd5cd3f17c1e075dfMD53TEXTDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txtDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txtExtracted texttext/plain80677http://repositorio.ufsm.br/bitstream/1/18003/4/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txt3da333c768373c40a79d1e07aa9f5152MD54THUMBNAILDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpgDIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpgIM Thumbnailimage/jpeg4433http://repositorio.ufsm.br/bitstream/1/18003/5/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpg8237f7c90756b140b3e0631367a8c00bMD551/180032019-08-24 03:01:29.312oai:repositorio.ufsm.br:1/18003TElDRU7Dh0EgREUgRElTVFJJQlVJw4fDg08gTsODTy1FWENMVVNJVkEKCkNvbSBhIGFwcmVzZW50YcOnw6NvIGRlc3RhIGxpY2Vuw6dhLCB2b2PDqiAobyBhdXRvciAoZXMpIG91IG8gdGl0dWxhciBkb3MgZGlyZWl0b3MgZGUgYXV0b3IpIGNvbmNlZGUgw6AgVW5pdmVyc2lkYWRlCkZlZGVyYWwgZGUgU2FudGEgTWFyaWEgKFVGU00pIG8gZGlyZWl0byBuw6NvLWV4Y2x1c2l2byBkZSByZXByb2R1emlyLCAgdHJhZHV6aXIgKGNvbmZvcm1lIGRlZmluaWRvIGFiYWl4byksIGUvb3UKZGlzdHJpYnVpciBhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gKGluY2x1aW5kbyBvIHJlc3VtbykgcG9yIHRvZG8gbyBtdW5kbyBubyBmb3JtYXRvIGltcHJlc3NvIGUgZWxldHLDtG5pY28gZQplbSBxdWFscXVlciBtZWlvLCBpbmNsdWluZG8gb3MgZm9ybWF0b3Mgw6F1ZGlvIG91IHbDrWRlby4KClZvY8OqIGNvbmNvcmRhIHF1ZSBhIFVGU00gcG9kZSwgc2VtIGFsdGVyYXIgbyBjb250ZcO6ZG8sIHRyYW5zcG9yIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbwpwYXJhIHF1YWxxdWVyIG1laW8gb3UgZm9ybWF0byBwYXJhIGZpbnMgZGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIHRhbWLDqW0gY29uY29yZGEgcXVlIGEgVUZTTSBwb2RlIG1hbnRlciBtYWlzIGRlIHVtYSBjw7NwaWEgYSBzdWEgdGVzZSBvdQpkaXNzZXJ0YcOnw6NvIHBhcmEgZmlucyBkZSBzZWd1cmFuw6dhLCBiYWNrLXVwIGUgcHJlc2VydmHDp8Ojby4KClZvY8OqIGRlY2xhcmEgcXVlIGEgc3VhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbyDDqSBvcmlnaW5hbCBlIHF1ZSB2b2PDqiB0ZW0gbyBwb2RlciBkZSBjb25jZWRlciBvcyBkaXJlaXRvcyBjb250aWRvcwpuZXN0YSBsaWNlbsOnYS4gVm9jw6ogdGFtYsOpbSBkZWNsYXJhIHF1ZSBvIGRlcMOzc2l0byBkYSBzdWEgdGVzZSBvdSBkaXNzZXJ0YcOnw6NvIG7Do28sIHF1ZSBzZWphIGRlIHNldQpjb25oZWNpbWVudG8sIGluZnJpbmdlIGRpcmVpdG9zIGF1dG9yYWlzIGRlIG5pbmd1w6ltLgoKQ2FzbyBhIHN1YSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gY29udGVuaGEgbWF0ZXJpYWwgcXVlIHZvY8OqIG7Do28gcG9zc3VpIGEgdGl0dWxhcmlkYWRlIGRvcyBkaXJlaXRvcyBhdXRvcmFpcywgdm9jw6oKZGVjbGFyYSBxdWUgb2J0ZXZlIGEgcGVybWlzc8OjbyBpcnJlc3RyaXRhIGRvIGRldGVudG9yIGRvcyBkaXJlaXRvcyBhdXRvcmFpcyBwYXJhIGNvbmNlZGVyIMOgIFVGU00Kb3MgZGlyZWl0b3MgYXByZXNlbnRhZG9zIG5lc3RhIGxpY2Vuw6dhLCBlIHF1ZSBlc3NlIG1hdGVyaWFsIGRlIHByb3ByaWVkYWRlIGRlIHRlcmNlaXJvcyBlc3TDoSBjbGFyYW1lbnRlCmlkZW50aWZpY2FkbyBlIHJlY29uaGVjaWRvIG5vIHRleHRvIG91IG5vIGNvbnRlw7pkbyBkYSB0ZXNlIG91IGRpc3NlcnRhw6fDo28gb3JhIGRlcG9zaXRhZGEuCgpDQVNPIEEgVEVTRSBPVSBESVNTRVJUQcOHw4NPIE9SQSBERVBPU0lUQURBIFRFTkhBIFNJRE8gUkVTVUxUQURPIERFIFVNIFBBVFJPQ8ONTklPIE9VCkFQT0lPIERFIFVNQSBBR8OKTkNJQSBERSBGT01FTlRPIE9VIE9VVFJPIE9SR0FOSVNNTyBRVUUgTsODTyBTRUpBIEEgVUZTTQosIFZPQ8OKIERFQ0xBUkEgUVVFIFJFU1BFSVRPVSBUT0RPUyBFIFFVQUlTUVVFUiBESVJFSVRPUyBERSBSRVZJU8ODTyBDT01PClRBTULDiU0gQVMgREVNQUlTIE9CUklHQcOHw5VFUyBFWElHSURBUyBQT1IgQ09OVFJBVE8gT1UgQUNPUkRPLgoKQSBVRlNNIHNlIGNvbXByb21ldGUgYSBpZGVudGlmaWNhciBjbGFyYW1lbnRlIG8gc2V1IG5vbWUgKHMpIG91IG8ocykgbm9tZShzKSBkbyhzKQpkZXRlbnRvcihlcykgZG9zIGRpcmVpdG9zIGF1dG9yYWlzIGRhIHRlc2Ugb3UgZGlzc2VydGHDp8OjbywgZSBuw6NvIGZhcsOhIHF1YWxxdWVyIGFsdGVyYcOnw6NvLCBhbMOpbSBkYXF1ZWxhcwpjb25jZWRpZGFzIHBvciBlc3RhIGxpY2Vuw6dhLgoKBiblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/ONGhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.comopendoar:2019-08-24T06:01:29Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.por.fl_str_mv Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
dc.title.alternative.eng.fl_str_mv Factors influencing the treatment of osteoporosis in postmenopausal women
title Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
spellingShingle Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
Montagner, Lia Mara Zamberlan
Osteoporose
Pós-menopausa
Tratamento
Aderência
Densitometria óssea
Informação
Osteoporosis
Post-menopause
Treatment
Adherence
Bone densitometry
Information
CNPQ::CIENCIAS DA SAUDE::FARMACIA
title_short Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
title_full Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
title_fullStr Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
title_full_unstemmed Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
title_sort Fatores que influenciam o tratamento da osteoporose em mulheres na pós-menopausa
author Montagner, Lia Mara Zamberlan
author_facet Montagner, Lia Mara Zamberlan
author_role author
dc.contributor.advisor1.fl_str_mv Premaor, Melissa Orlandin
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/1919693261808995
dc.contributor.advisor-co1.fl_str_mv Comim, Fabio Vasconcellos
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/5119233991388822
dc.contributor.referee1.fl_str_mv Moresco, Rafael Noal
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/2269922709577261
dc.contributor.referee2.fl_str_mv Gomes, Patrícia
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/7622203730579234
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/7553265208772531
dc.contributor.author.fl_str_mv Montagner, Lia Mara Zamberlan
contributor_str_mv Premaor, Melissa Orlandin
Comim, Fabio Vasconcellos
Moresco, Rafael Noal
Gomes, Patrícia
dc.subject.por.fl_str_mv Osteoporose
Pós-menopausa
Tratamento
Aderência
Densitometria óssea
Informação
topic Osteoporose
Pós-menopausa
Tratamento
Aderência
Densitometria óssea
Informação
Osteoporosis
Post-menopause
Treatment
Adherence
Bone densitometry
Information
CNPQ::CIENCIAS DA SAUDE::FARMACIA
dc.subject.eng.fl_str_mv Osteoporosis
Post-menopause
Treatment
Adherence
Bone densitometry
Information
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS DA SAUDE::FARMACIA
description Introduction: Osteoporosis is a disorder associated with bone fragility and increased risk of fractures. It may lead to serious physical, psychosocial and economic grievances. Therefore, strategies for early diagnosis of patients at high risk for fractures have been recommended to institute treatment. Nonetheless, despite the availability of effective drugs for the prevention of bone fractures, a low adhesion to them has been observed. Objective: the aim of this study was to identify possible factors associated with the use of treatment to prevent fractures in women after menopause. Methodology: This analytical cross-sectional study was carried out from March 1 to August 31, 2013. Postmenopausal women aged over 55 who attended the Basic Health Units in the city of Santa Maria (Brazil) were included. Women with communication difficulties were excluded. All information was obtained by a standardized questionnaire. Women were considered as currently on treatment when taking one of the following drugs at the moment of the survey: alendronate, risedronate, pamidronate, zoledronic acid, raloxifene, estrogen, calcitonin, teriparatide or strontium ranelate. Past treatment was considered when the women had taken any of those drugs in the past but did not presently take it. Results: Of the 1025 subjects included, 82 (8%) were currently on treatment, 59 (5.7%) had past treatment and 884 (86.3%) never treated. Factors independently associated with treatment (current or past) were performing a bone densitometry (BMD) scan, having a diagnosis of osteoporosis by a BMD scan, and having received information about osteoporosis. Conclusion: These results suggest that properly informing patients during the consultation and the popularization of BMD scan may have a positive impact on adherence to treatment of osteoporosis and primary and secondary prevention of fractures.
publishDate 2016
dc.date.issued.fl_str_mv 2016-03-02
dc.date.accessioned.fl_str_mv 2019-08-23T18:30:26Z
dc.date.available.fl_str_mv 2019-08-23T18:30:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/18003
url http://repositorio.ufsm.br/handle/1/18003
dc.language.iso.fl_str_mv por
language por
dc.relation.cnpq.fl_str_mv 400300000005
dc.relation.confidence.fl_str_mv 600
dc.relation.authority.fl_str_mv ac7b8248-d4ca-4014-81f1-9c9db5a4eabd
f9e59491-b644-45ef-8ba3-6f9a29f72e86
3ffbe810-4010-4acb-b64f-571aa21e74e5
05b536c5-19fb-4cae-9d69-46730a16ed09
ef9eef3d-25fd-4747-ae4d-5fed54a703b1
dc.rights.driver.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Farmacologia
dc.publisher.initials.fl_str_mv UFSM
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Farmacologia
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Centro de Ciências da Saúde
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações do UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Biblioteca Digital de Teses e Dissertações do UFSM
collection Biblioteca Digital de Teses e Dissertações do UFSM
bitstream.url.fl_str_mv http://repositorio.ufsm.br/bitstream/1/18003/1/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf
http://repositorio.ufsm.br/bitstream/1/18003/2/license_rdf
http://repositorio.ufsm.br/bitstream/1/18003/3/license.txt
http://repositorio.ufsm.br/bitstream/1/18003/4/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.txt
http://repositorio.ufsm.br/bitstream/1/18003/5/DIS_PPGFARMACOLOGIA_2016_MONTAGNER_LIA.pdf.jpg
bitstream.checksum.fl_str_mv 1e8f3eeab68c077625e2b4bafad6c077
4460e5956bc1d1639be9ae6146a50347
2f0571ecee68693bd5cd3f17c1e075df
3da333c768373c40a79d1e07aa9f5152
8237f7c90756b140b3e0631367a8c00b
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações do UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com
_version_ 1801485460360396800