Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico

Detalhes bibliográficos
Ano de defesa: 2025
Autor(a) principal: Maracci, Lucas Machado
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Brasil
UFSM
Programa de Pós-Graduação em Ciências Odontológicas
Centro de Ciências da Saúde
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://repositorio.ufsm.br/handle/1/36787
Resumo: Cone beam computed tomography (CBCT) is considered the reference examination for the evaluation of hard tissues of the temporomandibular joint (TMJ), especially in cases of suspected degenerative joint disease (DJD). However, acquisition and assessment parameters may influence TMJ evaluation. Furthermore, CBCT has limitations related to cost, availability, and, mainly, to higher radiation dose compared with radiographic exams such as panoramic radiography (PR) and planigraphy (PL). The present thesis aimed to map the parameters related to CBCT acquisition, examiner calibration, and assessment criteria and their impact on DJD detection (Article 1), and to evaluate the diagnostic performance of PR and PL for DJD detection, compared with CBCT, as well as the impact of the examination on disease classification (Article 2). Article 1 consisted of a scoping review including 24 in vivo studies with adult individuals that used CBCT to evaluate degenerative changes and discriminated technical acquisition parameters and assessment criteria. Wide variation in CBCT acquisition parameters was verified (voxel: 0.076 mm to 0.3 mm; kV: 70 to 120; mA: 3 to 38), with voxel size apparently not influencing DJD detection. Ahmad et al.’s criteria (2009) were the most frequently used for TMJ assessment (n=10). The most frequently assessed condylar changes were erosion, flattening, sclerosis, osteophyte, and subcortical cyst. Only five studies provided calibration data (kappa), with values ranging from 0.30 to 0.79 (interexaminer) and 0.69 to 0.88 (intraexaminer). Article 2 was a diagnostic efficacy study with imaging examinations (CBCT and PR and/or PL) of 83 symptomatic adult patients. Three calibrated examiners evaluated the exams, using the criteria of Ahmad et al. (2009). Specificity, sensitivity, negative predictive value (NPV), positive predictive value (PPV), and area under the curve (AUC) were calculated for each exam; Friedman and Wilcoxon tests were used to compare the exams regarding DJD classification. Interexaminer reproducibility ranged from low to substantial across all exams. Radiographic examinations showed high sensitivity (68%–98%) and low specificity (2%–32%) for condylar flattening and erosion and temporal sclerosis, while other changes presented intermediate and similar values among the exams. PPV (77%), NPV (91%), and AUC (0.75) were adequate only for osteophyte in PL. PR and PL confirmed approximately 73% of the classification results obtained with CBCT, with no significant difference (p>0.05). The results of this thesis indicate a lack of calibration and inconsistencies in the standardization of TMJ assessment criteria. Regarding the diagnostic performance of imaging exams, PR and PL show low diagnostic accuracy in identifying alterations individually, although a diagnostic thinking process similar to CBCT in DJD classification.
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spelling Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnósticoDegenerative disorders of the temporomandibular joint: impact of imaging examinations and technical parameters on diagnosisTranstornos da articulação temporomandibularDoença articular degenerativaTomografia computadorizada de feixe cônicoExames bidimensionaisTemporomandibular joint disordersDegenerative joint diseaseCone beam computed tomographyTwo-dimensional examsCNPQ::CIENCIAS DA SAUDE::ODONTOLOGIACone beam computed tomography (CBCT) is considered the reference examination for the evaluation of hard tissues of the temporomandibular joint (TMJ), especially in cases of suspected degenerative joint disease (DJD). However, acquisition and assessment parameters may influence TMJ evaluation. Furthermore, CBCT has limitations related to cost, availability, and, mainly, to higher radiation dose compared with radiographic exams such as panoramic radiography (PR) and planigraphy (PL). The present thesis aimed to map the parameters related to CBCT acquisition, examiner calibration, and assessment criteria and their impact on DJD detection (Article 1), and to evaluate the diagnostic performance of PR and PL for DJD detection, compared with CBCT, as well as the impact of the examination on disease classification (Article 2). Article 1 consisted of a scoping review including 24 in vivo studies with adult individuals that used CBCT to evaluate degenerative changes and discriminated technical acquisition parameters and assessment criteria. Wide variation in CBCT acquisition parameters was verified (voxel: 0.076 mm to 0.3 mm; kV: 70 to 120; mA: 3 to 38), with voxel size apparently not influencing DJD detection. Ahmad et al.’s criteria (2009) were the most frequently used for TMJ assessment (n=10). The most frequently assessed condylar changes were erosion, flattening, sclerosis, osteophyte, and subcortical cyst. Only five studies provided calibration data (kappa), with values ranging from 0.30 to 0.79 (interexaminer) and 0.69 to 0.88 (intraexaminer). Article 2 was a diagnostic efficacy study with imaging examinations (CBCT and PR and/or PL) of 83 symptomatic adult patients. Three calibrated examiners evaluated the exams, using the criteria of Ahmad et al. (2009). Specificity, sensitivity, negative predictive value (NPV), positive predictive value (PPV), and area under the curve (AUC) were calculated for each exam; Friedman and Wilcoxon tests were used to compare the exams regarding DJD classification. Interexaminer reproducibility ranged from low to substantial across all exams. Radiographic examinations showed high sensitivity (68%–98%) and low specificity (2%–32%) for condylar flattening and erosion and temporal sclerosis, while other changes presented intermediate and similar values among the exams. PPV (77%), NPV (91%), and AUC (0.75) were adequate only for osteophyte in PL. PR and PL confirmed approximately 73% of the classification results obtained with CBCT, with no significant difference (p>0.05). The results of this thesis indicate a lack of calibration and inconsistencies in the standardization of TMJ assessment criteria. Regarding the diagnostic performance of imaging exams, PR and PL show low diagnostic accuracy in identifying alterations individually, although a diagnostic thinking process similar to CBCT in DJD classification.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPESA tomografia computadorizada de feixe cônico (TCFC) é considerada o exame de referência para a avaliação dos tecidos duros da articulação temporomandibular (ATM), especialmente em casos de suspeita de doença articular degenerativa (DAD). Todavia, os parâmetros de aquisição e de avaliação podem influenciar a avaliação da ATM. Ademais, a TCFC apresenta limitações relacionadas ao custo, à disponibilidade e, principalmente, à maior dose de radiação se comparada com exames radiográficos como panorâmica (RP) e planigrafia (PL). A presente tese teve como objetivo mapear os parâmetros relacionados à aquisição da TCFC, à calibragem do examinador e aos critérios de avaliação e seu impacto na detecção das DAD (Artigo 1) e avaliar a performance diagnóstica de RP e PL para a detecção de DAD, em comparação à TCFC, e o impacto do exame na classificação da doença (Artigo 2). O Artigo 1 caracteriza-se por uma revisão de escopo com inclusão de 24 estudos in vivo com indivíduos adultos que utilizaram TCFC para avaliar alterações degenerativas e que discriminaram parâmetros técnicos de aquisição e critérios utilizados para avaliação. Foi verificada ampla variação nos parâmetros de aquisição da TCFC (voxel: 0,076 mm a 0,3 mm; kV: 70 a 120; mA: 3 a 38), sendo que o tamanho do voxel parece não influenciar a detecção de DAD. O critério de Ahmad et al. (2009) foi o mais utilizado para avaliação da ATM (n=10). As alterações condilares mais avaliadas foram erosão, aplainamento, esclerose, osteófito e cisto subcortical. Apenas cinco estudos forneceram dados de calibragem (kappa), cujos valores ficaram entre 0,30 e 0,79 (interexaminador) e entre 0,69 e 0,88 (intraexaminador). O Artigo 2 foi um estudo de eficácia diagnóstica com exames por imagem (TCFC e RP e/ou PL) de 83 pacientes adultos sintomáticos. Três examinadores calibrados avaliaram os exames, utilizando os critérios de Ahmad et al. (2009). Especificidade, sensibilidade, valor preditivo negativo (VPN), valor preditivo positivo (VPP) e área sob a curva (AUC) foram calculados para cada exame; os testes de Friedman e Wilcoxon foram utilizados para comparação dos exames quanto à classificação de DAD. A reprodutibilidade interexaminador variou de baixa a substancial. Os exames radiográficos apresentaram alta sensibilidade (68%–98%) e baixa especificidade (2%–32%) para aplainamento e erosão condilares e esclerose temporal, enquanto as demais alterações apresentaram valores intermediários e semelhantes entre os exames. VPP (77%), VPN (91%) e AUC (0.75) foram adequados apenas para osteófito em PL. RP e PL confirmaram 73% dos resultados das classificações obtidas com TCFC, sem diferença significativa (p>0.05). Os resultados desta tese apontam falta de calibração e inconsistências na padronização dos critérios de avaliação da ATM. Quanto à performance diagnóstica dos exames por imagem, RP e PL apresentam baixo desempenho diagnóstico na identificação das alterações individualmente, embora pensamento diagnóstico semelhante à TCFC quanto à classificação de DAD.Universidade Federal de Santa MariaBrasilUFSMPrograma de Pós-Graduação em Ciências OdontológicasCentro de Ciências da SaúdeLiedke, Gabriela Salatinohttp://lattes.cnpq.br/1481970655003887Spin-Neto, RubensAssaf, Débora do CantoVizzotto, Mariana BoessioDamian, Melissa FeresMaracci, Lucas Machado2025-11-12T11:56:08Z2025-11-12T11:56:08Z2025-10-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/36787porAttribution-NonCommercial-NoDerivatives 4.0 Internationalinfo:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2025-11-12T11:56:08Zoai:repositorio.ufsm.br:1/36787Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/PUBhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.com||manancial@ufsm.bropendoar:2025-11-12T11:56:08Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
Degenerative disorders of the temporomandibular joint: impact of imaging examinations and technical parameters on diagnosis
title Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
spellingShingle Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
Maracci, Lucas Machado
Transtornos da articulação temporomandibular
Doença articular degenerativa
Tomografia computadorizada de feixe cônico
Exames bidimensionais
Temporomandibular joint disorders
Degenerative joint disease
Cone beam computed tomography
Two-dimensional exams
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
title_full Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
title_fullStr Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
title_full_unstemmed Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
title_sort Desordens degenerativas da articulação temporomandibular: impacto do exame por imagem e parâmetros técnicos no diagnóstico
author Maracci, Lucas Machado
author_facet Maracci, Lucas Machado
author_role author
dc.contributor.none.fl_str_mv Liedke, Gabriela Salatino
http://lattes.cnpq.br/1481970655003887
Spin-Neto, Rubens
Assaf, Débora do Canto
Vizzotto, Mariana Boessio
Damian, Melissa Feres
dc.contributor.author.fl_str_mv Maracci, Lucas Machado
dc.subject.por.fl_str_mv Transtornos da articulação temporomandibular
Doença articular degenerativa
Tomografia computadorizada de feixe cônico
Exames bidimensionais
Temporomandibular joint disorders
Degenerative joint disease
Cone beam computed tomography
Two-dimensional exams
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
topic Transtornos da articulação temporomandibular
Doença articular degenerativa
Tomografia computadorizada de feixe cônico
Exames bidimensionais
Temporomandibular joint disorders
Degenerative joint disease
Cone beam computed tomography
Two-dimensional exams
CNPQ::CIENCIAS DA SAUDE::ODONTOLOGIA
description Cone beam computed tomography (CBCT) is considered the reference examination for the evaluation of hard tissues of the temporomandibular joint (TMJ), especially in cases of suspected degenerative joint disease (DJD). However, acquisition and assessment parameters may influence TMJ evaluation. Furthermore, CBCT has limitations related to cost, availability, and, mainly, to higher radiation dose compared with radiographic exams such as panoramic radiography (PR) and planigraphy (PL). The present thesis aimed to map the parameters related to CBCT acquisition, examiner calibration, and assessment criteria and their impact on DJD detection (Article 1), and to evaluate the diagnostic performance of PR and PL for DJD detection, compared with CBCT, as well as the impact of the examination on disease classification (Article 2). Article 1 consisted of a scoping review including 24 in vivo studies with adult individuals that used CBCT to evaluate degenerative changes and discriminated technical acquisition parameters and assessment criteria. Wide variation in CBCT acquisition parameters was verified (voxel: 0.076 mm to 0.3 mm; kV: 70 to 120; mA: 3 to 38), with voxel size apparently not influencing DJD detection. Ahmad et al.’s criteria (2009) were the most frequently used for TMJ assessment (n=10). The most frequently assessed condylar changes were erosion, flattening, sclerosis, osteophyte, and subcortical cyst. Only five studies provided calibration data (kappa), with values ranging from 0.30 to 0.79 (interexaminer) and 0.69 to 0.88 (intraexaminer). Article 2 was a diagnostic efficacy study with imaging examinations (CBCT and PR and/or PL) of 83 symptomatic adult patients. Three calibrated examiners evaluated the exams, using the criteria of Ahmad et al. (2009). Specificity, sensitivity, negative predictive value (NPV), positive predictive value (PPV), and area under the curve (AUC) were calculated for each exam; Friedman and Wilcoxon tests were used to compare the exams regarding DJD classification. Interexaminer reproducibility ranged from low to substantial across all exams. Radiographic examinations showed high sensitivity (68%–98%) and low specificity (2%–32%) for condylar flattening and erosion and temporal sclerosis, while other changes presented intermediate and similar values among the exams. PPV (77%), NPV (91%), and AUC (0.75) were adequate only for osteophyte in PL. PR and PL confirmed approximately 73% of the classification results obtained with CBCT, with no significant difference (p>0.05). The results of this thesis indicate a lack of calibration and inconsistencies in the standardization of TMJ assessment criteria. Regarding the diagnostic performance of imaging exams, PR and PL show low diagnostic accuracy in identifying alterations individually, although a diagnostic thinking process similar to CBCT in DJD classification.
publishDate 2025
dc.date.none.fl_str_mv 2025-11-12T11:56:08Z
2025-11-12T11:56:08Z
2025-10-20
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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dc.identifier.uri.fl_str_mv http://repositorio.ufsm.br/handle/1/36787
url http://repositorio.ufsm.br/handle/1/36787
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language por
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info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
UFSM
Programa de Pós-Graduação em Ciências Odontológicas
Centro de Ciências da Saúde
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
UFSM
Programa de Pós-Graduação em Ciências Odontológicas
Centro de Ciências da Saúde
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
instacron:UFSM
instname_str Universidade Federal de Santa Maria (UFSM)
instacron_str UFSM
institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
collection Manancial - Repositório Digital da UFSM
repository.name.fl_str_mv Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)
repository.mail.fl_str_mv atendimento.sib@ufsm.br||tedebc@gmail.com||manancial@ufsm.br
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