Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral

Detalhes bibliográficos
Ano de defesa: 2024
Autor(a) principal: Ziani, Jarbas da Silva
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
dARK ID: ark:/26339/00130000197fr
Idioma: por
Instituição de defesa: Universidade Federal de Santa Maria
Brasil
Enfermagem
UFSM
Programa de Pós-Graduação em Enfermagem
Centro de Ciências da Saúde
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: http://repositorio.ufsm.br/handle/1/33980
Resumo: Introduction: four decades after the beginning of the human immunodeficiency virus epidemic, it is still known for its relevance on the world stage. However, with the advent of antiretroviral therapy, the human immunodeficiency virus became a chronic health condition with potential for control, an aspect that has been constantly decreasing the number of people who die as a result of AIDS, but falls short of elimination goals, especially in Brazil. Despite interventions to promote early diagnosis and treatment of HIV, hospitalization and mortality related to advanced HIV disease remain a Significant public health problem. Objectives: to relate the clinical and epidemiological profile of people living with HIV hospitalized with the abandonment of antiretroviral therapy. Method: retrospective cohort study of documentary nature, conducted with 219 people living with HIV who were hospitalized in a medium-sized hospital in the city of Santa Maria. A questionnaire prepared by the author of the study was used, and evaluated by expertise in the area. Pearson's Chi-Square and Fisher's Exact Test were used as a descriptive data analysis technique, in addition to multiple correspondence analysis. Results: of the 219 study participants, 98 (44.7%) abandoned treatment. The average of months of abandonment was 14.22 (SD± 8.04) and median of 12 months, with a minimum period of 5 months and a maximum of 47 months. Regarding the cloister analysis, it was identified that group two was associated with treatment abandonment and the worst prognoses, such as being male, black skin color, education level less than eight years of study and not having a fixed partnership. As for the clinical characteristics, it was alcoholic, high CV, CD4+ LT less than 200 cells/mm3 and a clinical picture compatible with AIDS. Also, regarding the relationship with the health system, they were diagnosed in the PHC, sought the service due to signs and symptoms, travel time greater than 31 minutes for the removal of the ART, had a previous history of treatment abandonment, registration of three or more ART regimens and had an association with the death outcome.Conclusion: finally, the study corroborates with the profile already known in the literature, signaling probable failure in the actions implemented in the long term and lack of new strategies for real impact on prevention, early detection and timely treatment, avoiding hospitalizations for this condition.
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spelling Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviralHospitalization of people living with HIV: characteristics related to abandonment of antiretroviral treatmentVírus da imunodeficiência humanaSíndrome da imunodeficiência adquiridaAbandono da terapia antirretroviralHospitalizaçãoHuman immunodeficiency virusAcquired immunodeficiency syndromeAbandonment of antiretroviral therapyHospitalizationCNPQ::CIENCIAS DA SAUDE::ENFERMAGEMIntroduction: four decades after the beginning of the human immunodeficiency virus epidemic, it is still known for its relevance on the world stage. However, with the advent of antiretroviral therapy, the human immunodeficiency virus became a chronic health condition with potential for control, an aspect that has been constantly decreasing the number of people who die as a result of AIDS, but falls short of elimination goals, especially in Brazil. Despite interventions to promote early diagnosis and treatment of HIV, hospitalization and mortality related to advanced HIV disease remain a Significant public health problem. Objectives: to relate the clinical and epidemiological profile of people living with HIV hospitalized with the abandonment of antiretroviral therapy. Method: retrospective cohort study of documentary nature, conducted with 219 people living with HIV who were hospitalized in a medium-sized hospital in the city of Santa Maria. A questionnaire prepared by the author of the study was used, and evaluated by expertise in the area. Pearson's Chi-Square and Fisher's Exact Test were used as a descriptive data analysis technique, in addition to multiple correspondence analysis. Results: of the 219 study participants, 98 (44.7%) abandoned treatment. The average of months of abandonment was 14.22 (SD± 8.04) and median of 12 months, with a minimum period of 5 months and a maximum of 47 months. Regarding the cloister analysis, it was identified that group two was associated with treatment abandonment and the worst prognoses, such as being male, black skin color, education level less than eight years of study and not having a fixed partnership. As for the clinical characteristics, it was alcoholic, high CV, CD4+ LT less than 200 cells/mm3 and a clinical picture compatible with AIDS. Also, regarding the relationship with the health system, they were diagnosed in the PHC, sought the service due to signs and symptoms, travel time greater than 31 minutes for the removal of the ART, had a previous history of treatment abandonment, registration of three or more ART regimens and had an association with the death outcome.Conclusion: finally, the study corroborates with the profile already known in the literature, signaling probable failure in the actions implemented in the long term and lack of new strategies for real impact on prevention, early detection and timely treatment, avoiding hospitalizations for this condition.INTRODUÇÃO: Após quatro décadas do início da epidemia do vírus da imunodeficiência humana, ela ainda é conhecida por sua relevância no cenário mundial. Todavia, com o advento da Terapia antirretroviral o vírus da imunodeficiência humana passou a ser uma condição crônica de saúde com potencial de controle, aspecto que vem diminuído constantemente o número de pessoas que vem a óbito em decorrência da aids, mas fica aquém das metas de eliminação, especialmente no Brasil. Apesar das intervenções para promover o diagnóstico e tratamento precoces do HIV, a hospitalização e a mortalidade relacionadas à doença avançada pelo HIV continuam sendo um problema significativo de saúde pública. OBJETIVO: Relacionar o perfil clínico e epidemiológico das pessoas que vivem com HIV hospitalizadas com o abandono da terapia antirretroviral. MÉTODO: Estudo de coorte retrospectivo de caráter documental, realizado com 219 pessoas vivendo com HIV que estavam hospitalizadas em um hospital de médio porte do município de Santa Maria. Utilizou-se um questionário elaborado pelo autor do estudo, e avaliado por expertises da área. Usou-se como técnica de análise de dados descritiva, testes de associação Qui-Quadrado de Pearson e Teste Exato de Fisher, além da análise de correspondência múltipla. RESULTADOS: Dos 219 participantes do estudo, 98 (44,7%) abandonaram o tratamento. A média de meses do abandono foi de 14,22 (DP± 8,04) e mediana de 12 meses, com período mínimo de 5 meses e máximo de 47 meses. Em relação a análise de claustre, identificou-se que o grupo dois estava associado ao abandono do tratamento e os piores prognósticos, tais como, ser do sexo masculino, da cor de pele preta, nível de escolaridade menor de oito anos de estudo e não possuir parceria fixa. Quanto as características clínicas, deu-se ser etilistas, CV alta, LT CD4+ menor que 200 células/mm3 e quadro clínico compatível a aids. Ainda, quanto à relação com o sistema de saúde, esses foram diagnosticados na APS, buscaram o serviço devido a sinais e sintomas, tempo de deslocamento superior a 31 minutos para a retirada da TARV, apresentavam histórico prévio de abandono do tratamento, registro de três ou mais esquemas de TARV e teve associação com o desfecho óbito. CONCLUSÃO: Por fim, o estudo corrobora com o perfil já conhecido na literatura, sinalizando provável falência nas ações implementadas a longo prazo e carência de novas estratégias para real impacto na prevenção, detecção precoce e tratamento oportuno, evitando as internações por essa condição.Universidade Federal de Santa MariaBrasilEnfermagemUFSMPrograma de Pós-Graduação em EnfermagemCentro de Ciências da SaúdeCorcini, Laís Mara Caetano da Silvahttp://lattes.cnpq.br/3959038836778303Härter, JeniferPadoin, Stela Maris de MelloZamberlan, ClaudiaZiani, Jarbas da Silva2025-02-03T11:15:36Z2025-02-03T11:15:36Z2024-11-22info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://repositorio.ufsm.br/handle/1/33980ark:/26339/00130000197frporAttribution-NonCommercial-NoDerivatives 4.0 Internationalinfo:eu-repo/semantics/openAccessreponame:Manancial - Repositório Digital da UFSMinstname:Universidade Federal de Santa Maria (UFSM)instacron:UFSM2025-02-03T11:15:37Zoai:repositorio.ufsm.br:1/33980Biblioteca Digital de Teses e Dissertaçõeshttps://repositorio.ufsm.br/PUBhttps://repositorio.ufsm.br/oai/requestatendimento.sib@ufsm.br||tedebc@gmail.com||manancial@ufsm.bropendoar:2025-02-03T11:15:37Manancial - Repositório Digital da UFSM - Universidade Federal de Santa Maria (UFSM)false
dc.title.none.fl_str_mv Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
Hospitalization of people living with HIV: characteristics related to abandonment of antiretroviral treatment
title Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
spellingShingle Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
Ziani, Jarbas da Silva
Vírus da imunodeficiência humana
Síndrome da imunodeficiência adquirida
Abandono da terapia antirretroviral
Hospitalização
Human immunodeficiency virus
Acquired immunodeficiency syndrome
Abandonment of antiretroviral therapy
Hospitalization
CNPQ::CIENCIAS DA SAUDE::ENFERMAGEM
title_short Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
title_full Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
title_fullStr Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
title_full_unstemmed Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
title_sort Hospitalização de Pessoas Vivendo com HIV: características relacionadas ao abandono do tratamento antirretroviral
author Ziani, Jarbas da Silva
author_facet Ziani, Jarbas da Silva
author_role author
dc.contributor.none.fl_str_mv Corcini, Laís Mara Caetano da Silva
http://lattes.cnpq.br/3959038836778303
Härter, Jenifer
Padoin, Stela Maris de Mello
Zamberlan, Claudia
dc.contributor.author.fl_str_mv Ziani, Jarbas da Silva
dc.subject.por.fl_str_mv Vírus da imunodeficiência humana
Síndrome da imunodeficiência adquirida
Abandono da terapia antirretroviral
Hospitalização
Human immunodeficiency virus
Acquired immunodeficiency syndrome
Abandonment of antiretroviral therapy
Hospitalization
CNPQ::CIENCIAS DA SAUDE::ENFERMAGEM
topic Vírus da imunodeficiência humana
Síndrome da imunodeficiência adquirida
Abandono da terapia antirretroviral
Hospitalização
Human immunodeficiency virus
Acquired immunodeficiency syndrome
Abandonment of antiretroviral therapy
Hospitalization
CNPQ::CIENCIAS DA SAUDE::ENFERMAGEM
description Introduction: four decades after the beginning of the human immunodeficiency virus epidemic, it is still known for its relevance on the world stage. However, with the advent of antiretroviral therapy, the human immunodeficiency virus became a chronic health condition with potential for control, an aspect that has been constantly decreasing the number of people who die as a result of AIDS, but falls short of elimination goals, especially in Brazil. Despite interventions to promote early diagnosis and treatment of HIV, hospitalization and mortality related to advanced HIV disease remain a Significant public health problem. Objectives: to relate the clinical and epidemiological profile of people living with HIV hospitalized with the abandonment of antiretroviral therapy. Method: retrospective cohort study of documentary nature, conducted with 219 people living with HIV who were hospitalized in a medium-sized hospital in the city of Santa Maria. A questionnaire prepared by the author of the study was used, and evaluated by expertise in the area. Pearson's Chi-Square and Fisher's Exact Test were used as a descriptive data analysis technique, in addition to multiple correspondence analysis. Results: of the 219 study participants, 98 (44.7%) abandoned treatment. The average of months of abandonment was 14.22 (SD± 8.04) and median of 12 months, with a minimum period of 5 months and a maximum of 47 months. Regarding the cloister analysis, it was identified that group two was associated with treatment abandonment and the worst prognoses, such as being male, black skin color, education level less than eight years of study and not having a fixed partnership. As for the clinical characteristics, it was alcoholic, high CV, CD4+ LT less than 200 cells/mm3 and a clinical picture compatible with AIDS. Also, regarding the relationship with the health system, they were diagnosed in the PHC, sought the service due to signs and symptoms, travel time greater than 31 minutes for the removal of the ART, had a previous history of treatment abandonment, registration of three or more ART regimens and had an association with the death outcome.Conclusion: finally, the study corroborates with the profile already known in the literature, signaling probable failure in the actions implemented in the long term and lack of new strategies for real impact on prevention, early detection and timely treatment, avoiding hospitalizations for this condition.
publishDate 2024
dc.date.none.fl_str_mv 2024-11-22
2025-02-03T11:15:36Z
2025-02-03T11:15:36Z
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dc.publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Enfermagem
UFSM
Programa de Pós-Graduação em Enfermagem
Centro de Ciências da Saúde
publisher.none.fl_str_mv Universidade Federal de Santa Maria
Brasil
Enfermagem
UFSM
Programa de Pós-Graduação em Enfermagem
Centro de Ciências da Saúde
dc.source.none.fl_str_mv reponame:Manancial - Repositório Digital da UFSM
instname:Universidade Federal de Santa Maria (UFSM)
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instname_str Universidade Federal de Santa Maria (UFSM)
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institution UFSM
reponame_str Manancial - Repositório Digital da UFSM
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