Prevalência, gravidade, fatores de risco e seguimento da sibilância em lactentes da região centro-sul de São Paulo, SP - Estudo Internacional de Sibilância em Lactentes (EISL)

• Ano de defesa: 2010
• Autor(a) principal: Dela Bianca, Ana Caroline Cavalcanti [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• dARK ID: ark:/48912/001300001ffz4
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: infant; wheezing; asthma; risk factors; Lactente; Sibilo; Questionário escrito; Estudos de prevalência; Fatores de risco
• Link de acesso: http://repositorio.unifesp.br/handle/11600/9972

Objectives: To study the risk factors for wheezing disorders, recurrent wheezing (three or more episodes) and severe recurrent wheezing (six or more episodes) in the first year of life, in infants living in the southern region of São Paulo, Brazil, employing the standardized protocol of the “Estudio Internacional de sibilancia en lactentes” (EISL) – phase 1. Methods: Parents of infants attended for routine evaluation and immunization in public health centers were interviewed in southern São Paulo city. All answered the standardized EISL’s written questionnaire between March 2005 and August 2006. Results: In this study, 1014 parents or caregivers completed the questionnaire correctly. Factors independently associated with risk of wheezing at the first year of life were: male gender, history of previous pneumonia, hospitalization due to pneumonia, asthmatic mother, attending day care, exposure to tobacco smoke, presence of dog, carpet or mold at home, skin allergy, more than five upper respiratory infections (URI) and first URI before six months of life. Presence of other pet, but not dog or cat, and white skin were protective for wheezing. History of previous pneumonia, daycare attendance, consumption of processed food, presence of a cat at home, to have had more than five URI episodes and a first URI before the age of sixth month were risk factors significantly associated with recurrent wheezing. For severe recurrent wheezing, the associated factors were: history of previous pneumonia, consumption of processed food daily and to have had more than five URI episodes in the first year of life and cesarean were protective factors. Conclusions: Most of these risk factors for wheezing could be avoided or controlled. Prospective studies about wheezing, especially in children with severe presentation, are needed to analyze the impact of these risk factors and the effect of preventive actions in the future.