Microbiota bacteriana aerobica conjuntival em pacientes diabeticos com hemoglobina glicada normal e alterada em duas cidades brasileira

• Ano de defesa: 2013
• Autor(a) principal: Moreno, Natalia Pimentel [UNIFESP]
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• dARK ID: ark:/48912/0013000028v2s
• Idioma: por
• Instituição de defesa: Universidade Federal de São Paulo (UNIFESP)
• Palavras-chave em Português: conjunctiva; microbiota; diabetes; glycated hemoglobin; conjuntiva; hemoglobina glicada
• Link de acesso: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=155259; http://repositorio.unifesp.br/handle/11600/46535

Aim: To study conjunctival aerobic bacterial microbiota of diabetic patients regarding diabetes management through glycated hemoglobin. Methods: A cross-sectional study was carried out with conjunctive smears of diabetic patients from both sexes and different ages, residents of two cities: Sorocaba (State of São Paulo) and Rio Branco (State of Acre). Control group was formed of non-diabetic patients. The sample composed of diabetic patients was considered as controlled when their glycated hemoglobin was ≤ 7%. Those whose glycated hemoglobin was > 7% were considered as non-controlled. The material obtained was sown in BHI liquid and it was seeded in culture media for aerobic bacteria (blood and chocolate agars) and bacterial growth was evaluated in a microbiology laboratory. Results: 120 eyes of 120 patients were included in this study. We observed a larger number of diabetic and non-diabetic patients aging from 61 to 70 years and also over 70 years and females. The percentage of cultures in which there was bacterial growth was greater in diabetic patients, and it was statistically significant (p <0.05). Among diabetic patients, there was no difference between bacterial growth in patients with normal and altered glycated hemoglobin and a greater tendency in diabetic patients with altered fasting glycemia. In Sorocaba, conjunctival bacterial growth was similar to Rio Branco. The most frequent microorganism in this study was Staphylococcus epidermidis, followed by Staphylococcus aureus, Proteus mirabilis and Escherichia coli. Regarding antibiotics tested in this study, there was good response of the isolated bacteria in both diabetic and non-diabetic groups. Conclusions: There was a greater conjunctival aerobic bacterial growth in diabetic patients compared to non-diabetic ones. There was no difference between patients with normal and altered glycated hemoglobin. The microorganisms found were similar