Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado

Detalhes bibliográficos
Ano de defesa: 2012
Autor(a) principal: Pelegrini, Stella lattes
Orientador(a): Liebano, Richard Eloin lattes
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Cidade de São Paulo
Programa de Pós-Graduação: Programa de Pós-Graduação Mestrado de Fisioterapia
Departamento: Pós-Graduação
País: Brasil
Palavras-chave em Português:
Terapia a laser
Medição da dor
Limiar da dor
Analgesia
Área do conhecimento CNPq:
FISIOTERAPIA E TERAPIA OCUPACIONAL
Link de acesso: https://repositorio.cruzeirodosul.edu.br/handle/123456789/1142
Resumo: Introdução: O laser de baixa potência (LBP) é utilizado como recurso terapêutico para controle da dor. Porém, ainda é questionado o seu real efeito como também a dosimetria mais eficaz para esse efeito analgésico. Objetivo: Avaliar o efeito local e sistêmico do LBP no limiar de dor por pressão em indivíduos saudáveis. Materiais e Métodos: 150 indivíduos distribuídos aleatoriamente em 5 grupos (n=30 por grupo): controle, laser placebo, 3J, 6J, 12J. Como instrumento para avaliar a dor foi utilizado algômetro de pressão em cinco tempos distintos. Na região da mão dominante do indivíduo foi realizado o laser e a algometria para verificar o efeito local e na região da perna dominante foi realizado somente a algometria para verificar efeito sistêmico do LBP. Resultados: Houve redução local do limiar de dor por pressão no grupo 3J em comparação com os grupos controle (p=0,0016) e placebo (p=0,004) e não houve alteração sistêmica do limiar de dor por pressão. Conclusão: O LBP quando utilizado com energia de 3J reduziu o limiar de dor por pressão local em indivíduos saudáveis, porém não houve alteração sistêmica
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spelling 2020-12-01T13:54:45Z2020-12-01T13:54:45Z2012-03-03https://repositorio.cruzeirodosul.edu.br/handle/123456789/1142Introdução: O laser de baixa potência (LBP) é utilizado como recurso terapêutico para controle da dor. Porém, ainda é questionado o seu real efeito como também a dosimetria mais eficaz para esse efeito analgésico. Objetivo: Avaliar o efeito local e sistêmico do LBP no limiar de dor por pressão em indivíduos saudáveis. Materiais e Métodos: 150 indivíduos distribuídos aleatoriamente em 5 grupos (n=30 por grupo): controle, laser placebo, 3J, 6J, 12J. Como instrumento para avaliar a dor foi utilizado algômetro de pressão em cinco tempos distintos. Na região da mão dominante do indivíduo foi realizado o laser e a algometria para verificar o efeito local e na região da perna dominante foi realizado somente a algometria para verificar efeito sistêmico do LBP. Resultados: Houve redução local do limiar de dor por pressão no grupo 3J em comparação com os grupos controle (p=0,0016) e placebo (p=0,004) e não houve alteração sistêmica do limiar de dor por pressão. Conclusão: O LBP quando utilizado com energia de 3J reduziu o limiar de dor por pressão local em indivíduos saudáveis, porém não houve alteração sistêmicaIntroduction: The low-power laser (LBP) is used as a therapeutic treatment for pain control. However, it is still questioned about the real effect and also the dosimetry more effective for this analgesic effect. Objective: To evaluate the local effect and systemic of LBP in pressure pain threshold in healthy subjects. Methods: 150 subjects randomized in 5 groups (n=30 per group): control, placebo laser, 3J, 6J, 12J. As an instrument for evaluate the pain was used a pressure algometer in five different times. In the region of the dominant hand of the individual and the laser was held algometry to determine the effect local and region of the dominant leg was held algometry to check only the systemic effect of LBP. Results: There was a reduction in local pressure pain threshold in the group 3J compared with control groups (p=0.0016) and placebo (p=0.004) and no systemic change on pressure pain threshold. Conclusion: LBP when used with energy 3J reduced the pain threshold by local pressure in healthy subjects, but there was no systemic illness. Keywords: laser therapy, pain measurement, pain threshold, analgesiaporUniversidade Cidade de São PauloPrograma de Pós-Graduação Mestrado de FisioterapiaUNICIDBrasilPós-GraduaçãoFISIOTERAPIA E TERAPIA OCUPACIONALTerapia a laserMedição da dorLimiar da dorAnalgesiaEfeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizadoinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisLiebano, Richard Eloinhttps://orcid.org/0000-0003-4795-6723http://lattes.cnpq.br/1397951221512127http://lattes.cnpq.br/4639003464164800Pelegrini, Stella1. International Association for the Study to Pain – IASP, 2010. Acesso em 10/04/2010 as 21h30 min. Disponível em http://www.iasp-pain.org. 2. Merkey H, Albe-Fessard DG, Bonica JJ, Carmon A, Dubner R, Kerr FWL, et al. Pain terms. A list with definitions and notes on usage. Recommended by IASP Subcommitte on Taxonomy. Pain. 1979;6(3):249-52. 3. Nes AG, Posso MB. Patients with moderate chemotherapy-induced mucositis: pain therapy using low intensity lasers. Int Nurs Rev. 2005; 52(1):68-72. 4. Moran F, Leonard T, Hawthorne S, Hughes CM, McCrum-Gardner E, Johnson MI, et al. Hypolgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensiy. J Pain. 2011;12(8):929-35. 5. Pantaleão MA, Laurino MF, Gallego NLG, Cabral CMN, Rakel B, Vance C, et al. Adjusting pulse amplitude during TENS application produces greater hypoalgesia. J Pain. 2010;12(5):581-90. 6. Johnson MI, Ghasala T. An investigation into the analgesic effect of different frequencies of the amplitude-modulated wave of interferencial current theraphy ob cold-induced pain in normal subjects. Arch Phys Med Rehabil. 2003;84:1387-94. 7. Sthephenson R, Walker EM. The analgesic effects of interferential current on cold-pressor pain in healthy subjects. A single blind trial of three IF current against sham IF and control. Arch Phys Theory and Prtice. 2003;19:99-107. 8. Fare JC, Nicolau RA. Clinical analysis of the effect of laser photobiomodulation (GaAs – 904nm) on temporomandibular joint dysfunction. Rev Bras Fisioter. 2008;12(1):37-42. 9. Beckerman H, Ble RA, Bouter LX, Cuyper HJ, Oostendorp RAB. The efficacy of laser therapy for musculoskeletal and skin disorders: a criteria-based meta-analysis of randomized clinical trials. Phys Ther. 1992;72(7):483-91. 10. Sooshtari SM, Badiee V, Taghizadeh SH, Grami MT. The effects of low level lser in clinical outcome and neurophysiological results of carpal tunnel syndrome. Electromyorg Clin Neurophysiol. 2008;48(5):229-31. 11. Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM. Efficacy of low-level laser therapy in the management of neck pin: a systematic review and meta-analysis of randomized placebo or active-treatment controlled trials. Lancet. 2009;374(9705):1897-908. 12. Lopes-Martins RA, Albertine R, Martins PSLL, Bjordal JM, Faria Neto HCC. Spontaneous effects of low-level laser therapy (650nm) in acute inflammatory mouse pleurisy induced by carrageenan. Photomed Laser Sugery. 2005;23(4):337-81. 13. Karu TI. Molecular mechanism of low-power lasertherapy. Lasers Life Sci. 1998;2:53-74. 14. Bolognani L, Majni G, Costato M, Milani M. ATPase and ATPsynthetase activity in myosin exposed to low power laser and pulsed electromagnetic fields. Biocelectrochem Bioenerg. 1993;32(2):155-64. 15. Colls JL. La terapia laser hoy. Barcelona: Centro Documentacion Laser de Meditec. 1986. 16. Peavy GM. Lasers and laser-tissue interaction. Vet Clin North Am Small Anim Pract. 2002;32(3):517-34. 17. Walker J. Relief from chronic pain by low laser irradiation. Neurosci Lett. 1983;43(2-3):339-44. 18. Herrero C. Los efectos terapeuticos. Bol Sociedad Español Láser Médico Quirúrgico. 1988;15(16):22-6. 19. Hansson TL. Infrared laser in the treatment of craniomandibular e disordrs, arthrogenous pain. J Prosthet Dent. 1989;61(5):614-7. 20. Ferreira DM, Zângaro RA, Villaverde AB, Cury Y, Frigo L, Piccol G, et al. Analgesic effect of He-Ne (632.8nm) low-level lasers therapy on acute inflammatory pain. Photomed Laser Surg. 2005;23(2):177-81. 21. Bjordal JM, Iversen JV, Aimbire F, Lopes-Martins RA. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Lasers Surg. 2006;24(2):158-68. 22. Lievens PC. Effects of laser treatment on the lymphatic sysem and wound healing. J Eur Med Laser Associ. 1988;1(2):12. 23. Honmura A, Yanase M, Obata J, Haruki E. Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation in rats. Lasers Surg Med. 1992;12(4):441-9. 24. Aimbire F, Albertine R, Magalhães RG, Lopes-Martins RA, Castro-Faria-Neto RA, Zângaro RA, et al. Effect of LLLT Ga-Al-As (685 nm) on LPS – induced inflammation of the airway and lung in the rat. Lasers Med Sci. 2005;20(1):11-20. 25. Albertini R, Aimbire F, Villaverde AB, Silva JÁ JR, Costa MS. Cox-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carraggenan-induced inflammation after low level laser therapy. Inflamm Res. 2007;56(6):228-9. 26. Correa F, Lopes Martins RA, Correa JC, Iversen VV, Joenson J, Bjordal JM. Low-level laser therapy (GAAS lambda = 904nm) reduces inflammatory all migration in mice with lipopolysaccharide-induced peritonitis. Photomed Laser Surg. 2007;25(4):245-9. 27. Boschi ES, Leite CE, Saciura VC, Caberlan E, Leenardelli A, Bitencourt S, et al. Anti-inflammatory effects of low-level laser therapy (660nm) in the early phase in carrageean-induced pleurisy in rat. Lasers Surg Med. 2008;40(7):500-8. 28. Morais NC, Barbosa AM, Vale ML, Villaverde AB, De Lima CJ, Cogo JC, et al. Anti-inflammatory effect of low-level laser and ligth-emitting diode in zymosan-induced arthritis. Photomed Laser Surg. 2010;28(2):227-32. 29. Abergel RP. Increased wound-healing rate in pig skin treated by Helium-Neon laser. Int Soc Optical Engin Proces. 1988:6–10. 30. Bihari, J & Mester, AR. The biostimulative effect of low level laser therapy on longstanding crural ulcers using Helium Neon laser, Helium Neon laser plus infrared lasers, and noncoherent light: preliminary report of a randomised double blind comparative study. Laser Ther. 1989;1(2):97. 31. Kucerová H, Dostálavá T, Himmeová L, Bartová J, Mazánek J. Low-level laser therapy after molar extraction. J Clin Laser Med Surg. 2000;18(6):309-15. 32. Benedicenti, A. La Valutazione Dell Effecto Del la Luce Laser 904nm Nella Circolazione Ematica in Vivo. Langa Grafica, Atlate di laserterapia Gênova. 1983:71–83. 33. Kubota, J & Ohshiro, T. The effects of diode laser low reactive level laser therapy (LLLT) on flap survival in a rat model. Laser Ther. 1989;1(3):127. 34. Karu T. Photobiology of low-power lasers effects. Health Phys. 1989;56(5):691-704. 35. Kitchen SS e Partridge CJ. A review of low level laser therapy. Physiother. 1991;77(3):161-8. 36. Bjordal JM, Lopes-Martins RA, Joensen J, Couppe C, Ljunggren AE, Stergioulos A. A systematic review with procedural assessments and meta-analysis of low level laser therapy in lateral elbow tendinopathy (tennis elbow). BMC Musculoskelet Disord. 2008;29:9-75. 37. Basford JR, Hallman HO, Matsumoto JY, Moyer SK, Buss JM, Baxter GD. Effects of 830nm continous wave laser diode irradiation on median nerve function in normal subjects. Lasers Surg Med. 1993;13(6):597-604. 38. Hadian M e Moghagdam, B. The effects of low power laser on electrophysiological parameters of sural nerve in normal subjects: a comparison between 670 and 780nm wavelengths. Acta Med Iran. 2003;41:138–42. 39. Laakson L, Richardson C, Cramond T. Pain scores and plasma beta-endorphin and ACTH levels in response to low level laser therapy – a possible mechanism of action. Presented at the 12th International Congress on Physical Therapy, Washington, DC, 1995. 40. Hagiwara S, Iwasaka H, Hasegawa A, Noguchi T. Pre-irradiation of blood by gallium aluminum arsenide (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats. Anesth Analg. 2008;107(3):1058–63. 41. Ceylan Y, Hizmetli S, Silig Y. The effects of infrared laser and medical treatments on pain and serotonin degradation products in patients with myofascial pain syndrome. A controlled trial. Rheumatol Int. 2004;24:260-3. 42. Mackler LS, Barry AJ, Perkins AI, Soucek MD. Effects of helium-neon laser irradiation on skin resistence and pain in patients with trigger points in the neck or back. Phys Ther. 1989;69(5):336-41. 43. Gur A, Karakoc KN, Cqevie R, Sarac J, Demir E. Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo-controlled trial. Laser Med Sci. 2002;17:57-61. 44. Sharma R, Thukral A, Kumar S, Bhargava SK. Effect of low level lasers in the Quervains tenosynovitis: Prospective study ultrasonographyc assessment. Physiother. 2002;88(12):730-4 45. Altan L, Bingo I, Aykac M, Yurtkuran M. Investigation of the effect of GaAs laser therapy on cervical myofascial pain syndrome. Rheumatol Int.2005;25:23-7. 46. Basford JR, Malanga GA, Krause DA, Harmsen WS. A randomized controlled evaluation of low-intensity laser therapy: plantar fasciitis. Arch Phys Med Rehabil. 1998;79:249-54. 47. Brosseau L, Wells G, Marchand S, Gaboury I, Stokes B, Morin M et al. Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand. Laser Surg Med. 2005;36:210-9. 48. Rochkind S, Rousso M, Nissan M, Villaverde M, Barr-Nea L, Rees DG. Systemic effects of low-power laser irradiation on the peripheral and central nervous system, cutaneous wound, and burns. Lasers Surg Med. 1989;9:174-82. 49. Sandoval-Ortiz MC, Mattiello-Rosa SM, Soares EG, Parizotto NA. Influência do laser de baixa potência nos níveis das proteínas plasmáticas de coelhos. Rev Bras Fisiot. 2003;7(3):187-94. 50. Hopkins JT, McLoda TA, Seegmiller JG, Baxter GD. Low-level laser therapy facilitates superficial wound healing in humans: A triple-blind, sham-controlled study. J Athl Train. 2004;39(3):223-9. 51. Ferreira MC, Brito VN, Gameiro J, Costa MRS, Vasconcellos ECS, Cruz-Hofling MAC. Effects of HeNe laser irradiation on experimental paracoccidioidomycotic lesions. J Photochem Photob B: Biol. 2006;84:141-9. 52. Hawkins D, Abrahamse H. Phototherapy – A treatment modality for wound healing and pain relief. J Biomed Res. 2007;10:99-109. 53. Rodrigo SM, Cunha A, Pozza DH, Blaya DS, Moraes JF, Weber JBB, et al. Analysis of the systemic effect of red and infrared laser therapy on wound repair. Photomed Laser Surg. 2009;27(6):929-35. 54. Schuhfried M, Korpan V, Silig Y. Helium-Neon laser irradiation: effect on the experimental pain threshold. Lasers Med Sci. 2000;15:169-73. 55. Doing GS e Simpson F. Randomization and allocation concealment: A pratical guide for researches. J Crit Care. 2005;20:187-91. 56. Scales DC, Adhikari NK. Maintaining allocation concealment: Following your SNOSE. J Crit Care. 2005;20:191-3. 57. Cowan S, McKenna J, McCrum-Gardner E, Johnson MI, Sluka KA, Walsh DM: An investigation of the hypoalgesic effectsof TENS delivered by a glove electrode. J Pain 2009; 10: 694-701. 58. Frey Law LA, Sluka Ka, McMullen T, Lee J, Nielsen LA, Nielsen TG. Acidic buffer induced muscle pain evokes refered pain and mechanical hyperalgesia in humans. Pain. 2008;140(2):254-64. 59. Nie HL, Nielsen TG, Nielsen LA. Spatial and temporal summation of pain evoked by mechanical pressure stimulation. Eur J of Pain. 2009;13:592-9. 60. Nielsen MM, Mortensen A, Sorensen JK, Simonsen O, Nielsen TG. Reduction of experimental muscle pain by passive physiological movements. Manual Therapy. 2009;14:101-9. 61. Chesterton LS, Barlas P, Foster NE, Lundeberg t, Wright CC, Baxter GD. Sensory Stimulation (TENS): effects of parameter manipulation on mechanical pain thresholds in healthy human subjects. Pain. 2002;99:253-62. 62. Chesterton LS, Foster NE, Wright CC, Baxter GD, Barlas P. Effects of TENS frequency, intensity and stimulation site parameter manipulation on pressure pain thresholds in healthy human subjects. Pain. 2003;106:73-80. 63. Rakel B, Cooper N, Adams HJ, Messer BR, Frey Law LA, Dannen DR, et al. A new transient sham TENS device allows for investigator blinding while delivering a true placebo treatment. J Pain 2010; 11:230-8. 64. Liebano RE, Rakel B, Vance CGT, Walsh DM, Sluka KA. An investigation of development of analgesic tolerance to TENS in humans. Pain. 2011;152(2):335-42. 65. Palmer ST, Steedman W, Martin DJ, Ravey J. Alteration of interferential current and transcutaneous electrical nerve stimulation frequency: effects on nerve excitation. Arch Phys Med Rehabil. 1999;80(9):1065-71. 66. Alves-Guerreiro J, Noble JG, Lowe AS, Walsh DM. The effect of three electrotherapeutic modalities upon peripheral nerve conduction and mechanical pain threshold. Clin Physiol. 2001; 21(6):704-11. 67. Minder PM, Noble JG, Alves-Guerreiro J, Hill ID, Lowe AS, Walsh DM, et al. Interferential therapy: lack of effect upon experimentally induced delayed onset muscle soreness. Clin Physiol Funct Imaging. 2002; 22(5):339-47. 68. Lowe As, McDowell BC, Walsh DM, Baxter GD, Allen JM. Failure to demonstrate any hypoalgesic effect of low intensity laser irradiation (830nm) of Erb’s point upon experimental ischaemic pain in human. Laser Surg Med. 1997;20:69-76. 69. Ferrante FM, Bearn L, Rothrock R, King L. Evidence against trigger point injection technique for the treatment of cervicothoracic myofascial pain with Botulinum Toxin Type A. Anesthesiology. 2005;103: 377-83. 70. Fischer AA. Pressure algometry over normal muscles. Standard values, validity and reproducibility of pressure threshold. Pain 1987;30(1):115–26. 71. Mokhtar B, Callaghan G, Baxter GD, Bell AJ, Allen JM. The possible significance of pulse repetition rate in lasermediated analgesia: A double blind placebo controlled investigation using experimental ischaemic pain. Proceedings of the Second Meeting of the International Laser Therapy Association. 1992:62. 72. Johnson MI, Tabasam G. An investigation into the analgesic effects of interferential currents and transcutaneous electrical nerve stimulation on experimentally induced ischemic pain in otherwise pain-free volunteers. Phys Ther. 2003;83(3):208-23. 73. Sumikura H, Andersen OK, Drewes AM, Arendt-Nielsen L. A comparison of hyperalgesia and nerogenic inflammation induced by melittin and capsaicin in humans. Neurosci Lett. 2003;337(3):147-50. 74. Drewes AM, Schipper KP, Dimcevski G, Petersen P, Gregersen H, Funch-Jensen P, Arendt-Nielsen L. Gut pain and hyperalgesia induced by capsaicin: a human experimental model. Pain. 2003;104(1-2):333-41. 75. Frot M, Feine JS, Bushnell MC. Sex differences in pain perception and anxiety. A psychophysical study with topical capsaicin. Pain. 2004;108(3):230-6. 76. Nussbaum EL e Dawnes L. Reliability of clinical pressure-pain algometric measurements obtained on consecutive days. Phys Ther. 1998;78(2):160-9. 77. Ogimoto T, Ogawa T, Sumiyoshi K, Matsuka Y, Koyono K. Pressure pain threshold determination in the oral mucosa: validity and reliability. J Oral Rehabil. 2002;29:620-6. 78. Farasy A, Meusen R. Pressure pain threshold in healthy subjects: influence of physical activity, history of low back pain factors and the use of endermology as a placebo-like treatment . J of Bodyw Mov Ther. 2003;7:53-61. 79. Prushansky T, Dvir Z, Defrin-Assa R. Reproducibility indices applied to cervical pressure pain threshold measurements in healthy subjects. Clinl J Pain. 2004;20:341-7. 80. Ylinen J, Takala EP, Kautianien H, Nykanen A, Pohyolainen N, et al. Effect of long-term neck muscle training on pressure pain threshold: a randomized controlled trial. Eur J Pain. 2005;9:673-81. 81. Cathcart S, Pritchard D. Reliability of pain threshold measurement in young adults. J Headache Pain. 2006;721-6. 82. Ylinen J, Nykãnen M, Kautiainen H, Hãkkinen A. Evaluation of repeatability of pressure algometry on the neck muscles for clinical use. Man Ther, 2007;12(2):192-7. 83. Chesterton LS, Sim J, Wright CC, Foster NE. Interrater reliability of algometry in measuring pressure pain threshold in healthy humans, using multiple raters. Clin J Pain. 2007;23(9):760-6. 84. Kinser AM, Sands WA, Stone MH. Reliability and validity of a pressure algometer. J Strength Cond Res. 2009;23(1):312-4. 85. Marques AP, Ferreira EAG, Matsutani LA, Pereira CAB, Assumpção A. Quantifying pain threshold and quality of life of fibromyalgia patients. Clin Rheumatol. 2005;24:266-71. 86. Egan TD, Kern SE, Muir KT, White JL. Remifentanil by bolus injection: a safety, pharmacokinetic, pharmacodynamic, and age effect investigation in human volunteers. Br J Anaesth. 2004;92(3):335-43. 87. Kern SE, Xie G, White JL, Egan TD. Opioid-hypnotic synergi. A response surface analyses of propofal-remifentanil pharmacodynamic interaction in volunteers. Anesthesiology. 2004;100:1373-81. 88. Tucker AP, Kim YI, Nadson R, Goodchild CS. Investigation of the patentiation of the analgesic effects of fentanyl by ketamine in humans: a double-blinded, randomized, placebo controlled, crossover study of experimental pain. BMC Anesthesiol. 2005;5(1):2. 89. Edwards J e Knowus N. Superficial dry needing and active stretching in the treatment of myofascial pain – A randomised controlled trial. Acup In Med. 2003;21(3):80-6. 90. Hou CR, Tsai LC, Cheng KF, Chung KC, Kong CZ. Immediate effects of various physical therapeutic modalities on cervical myofascial pain and trigger-point sensitivity. Arch Phys Med Rehabil. 2002;83:1406-14. 91. Baraniuk JN, Whalen G, Cunningham J, Clauw IJ. Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain. BMC Musculoskel Disord. 2004;5:48. 92. Poletto PR, Coury GHJC, Walsh IAP, Mattielo-Rosa SM. Correlação entre métodos de auto-relato e testes provocativos de avaliação da dor em indivíduos portadores de distúrbios osteomusculares relacionados ao trabalho. Rev Bras Fisioter. 2004;8(3):223-9. 93. Pinheiro AL, Cavalcanti ET, Pinheiro TI, Alves MJ, Manzi CT. Low-level laser therapy in the management of disorders of the maxillofacial region. J Clin Laser Med Surg. 1998;15:181–3. 94. Kreisler M, AI Haj H, Daublander M, Gotz H, Duschner H, Willershausen B, et al. Effect of diode laser irradiation on root surfaces in vitro. J Clin Laser Med Surg. 2002;20(2):63-9. 95. Chavantes MC. Laser em bio-medicina. São Paulo: Atheneu; 2009. 96. Baxter D. Laserterapia de baixa intensidade. In: Kitchen S. Eletroterapia prática baseada em evidências. São Paulo: 11ª ed; 2003. p. 171-89. 97. Baxter G, Allen J, Bell A. The effect of low energy density laser irradiation upon human median nerve conduction latencies. J Physiol. 1990;435:63. 98. Baxter GD, Allen AJ, Bell J, Ravey J, Diamantopoulos C. Effect of laser (830 nm) upon conduction in the median nerve. Laser Surg Med. 1991;3:79. 99. Toya S, Motegi M, Inomata K, Ohshiro T, Maeda T. Report on a computer-randomised double blind clinical trial to determine the effectiveness of the GaAlAs (830nm) diode laser for pain attenuation in selected pain groups. Laser Ther. 1994;6:143–8. 100. Baxter GC, Walsh DM., Allen JM, Lowe AS, Bell AJ. Effects of low intensity infrared laser irradiation upon conduction in the human median nerve in vivo. Exp Physiol. 1994;79: 227–34. 101. Bartllet W, Qyillen W, Gonzales J. Effect of gallium-aluminum-arsenid trple-diode laser on median nerve latency in human subjects. J Sport Rehabil. 1999;8:99-108. 102. Cambier D, Blom K, Witvrouw E, Ollevier G, Muynck M, Vanderstraeten G. The influence of low intensity infrared laser irradiation on conduction characteristics of peripheral nerve: a randomised, controlled, double blind study on the sural nerve. Lasers Med Sci. 2000;15:195-200. 103. Walsh DM, Baxter GD, Allen JM. Lack of effect of pulsed low-intensity infrared (820nm) laser irradiation on nerve conduction in the human superficial radical nerve. Lasers Surg Med. 2000;26:485-90. 104. Özdemir F, Birtane M, Kokino S. The clinical efficacy of low-power laser therapy on pain and function in cervical osteoarthritis. Clin Rheumatol. 2001;20:181–4. 105. Seidel U, Uhlemann C. A randomised controlled double-blind trial comparing dose laser therapy on acupuncture points and acupuncture for chronic cervical syndrome. Dtsch Z Akupunktur. 2002;45:258–69. 106. Chow RT, Barnsley LB, Heller GZ, Siddall PJ. A pilot study of low-power laser therapy in the management of chronic neck pain. J Musculoskelet. Pain 2004;12:71-81. 107. Gur A, Sarac AJ, Cevik R, Altindag O, Sarac S. Efficacy of 904nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: a double-blind and randomized-control. Lasers Surg Med. 2004;35:229–35. 108. Bjordal JM, Lopes-Martins RA, Iversen W. A randomised, placebo controlled Trial of low level laser therapy for activated Achilles Tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations. Br J Sports Med. 2005;40(1):76-80. 109. Chow, R.T., Barnsley, L.B., and Heller, G.Z. The effect of 300mW, 830nm laser on chronic neck pain: a double-blind, randomized, placebo-controlled study. Pain. 2006;124:201–10. 110. Dundar E, Evcik D, Samli F, Pusak H, Kavuncu V. The effect of gallium arsenide aluminum laser therapy in the management of cervical myofascial pain syndrome: a double blind, placebo-controlled. Clin Rheumatol 2006;26:930–4. 111. Kato MT, Kogawa EM, Santos CN, Conti PCR. TENS and low-level laser therapy in the management of temporomandibular disorders. J. Appl. Oral. Sci. 2006;14(2):130-5. 112. Chow R, David M, Armati P. 830-nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830-nm laser. J Peripher Nerv Syst. 2007;12:28–39. 113. Konstantinovic LM, Kanjuh ZM, Milovanovic AN, Cutovic MR, Djuovic AG, Savic VG, et al. Acute low back pain with radiculopathy: a double-blind, randomized, placebo-controlled study. Photomed Laser Surg. 2009;1-8. 114. Chow R, Armat P, Laakso EL, Bjordal JM, Baxter GD. Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review. Photomedicine and Laser Surgery. 2011:1-17. 115. Kramer JF, Sandrin M. Effect of low-power laser and white light on sensory conduction rate of the superficial radial nerve. Physiother Can. 1993;45:165–70. 116. Ilbuldu E, Cakmak A, Disci R, Aydin R. Comparison of laser, dry needling and placebo laser treatments in myofascial pain syndrome. Photomed Laser Surg. 2004; 22:306–11. 117. Aigner N, Fialka C, Radda C, Vecsei V. Adjuvant laser acupuncture in the treatment of whiplash injuries: a prospective, randomized placebo-controlled trial. Wien Klin Wochenschr. 2006;118:95–9. 118. Karu T. Primary and secondary mechanisms of action of visible to near-IR radiation on cell. J Photochem Photobiol B. 1999;49(1):1-7. 119. Low J, Reed A. Eletroterapia explicada: princípios e prática. 3ª ed. São Paulo: Manole; 2001. 120. Kosek E, Ekholm J, Hansson P. Pressure pain thresholds in different tissues in one body region. The influence of skin sensitivity in pressure algometry. Scand J Rehabil Med. 1999;31(2):89–93. 121. Leffler AS, Hansson P, Kosek E. Somatosensory perception in a remote pain-free area and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from long-term trapezius myalgia. Eur J Pain. 2002;6(2):149–159 122. Leffler AS, Hansson P, Kosek E. Somatosensory perception in patients suffering from long-term trapezius myalgia at the site overlying the most painful part of the muscle and in an area of pain referral. Eur J Pain. 2003;7(3):267–276 123. Bjordal J, Couppe C, Chow R, Tuner J, Ljunggren A. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother. 2003;49:107–16. 124. Irvine, J Chong SL, Amrjani N, Chan KM. Double-blind randomized controlled trial of LLLT in carpal tunnel syndrome. Muscle Nerve. 2004;30:182–7. 125. Gross AR, Goldsmith C, Howing JL, Haines T, Peloso P, Aker P, et al. Conservative management of mechanical neck disorders: a systematic review. J Rheumatol. 2007;34(5):1083-102. 126. Bjordal J, Johnson MI, Lopes-Martins RA, Bogen B, Chow R, Ljunggren AE. Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomized placebo-controlled trials. BMC Musculoskelet Disord. 2007;8(51). 127. Bjordal J, Couppe C, Ljunggren AE. Low-level laser therapy for tendinopathy: evidence of a dose-response pattern. Phys Ther. 2001;6:91-9. 128. Lowe A, Baxter G, Walsh D, Allen J. Effect of low-intensity laser irradiation (830 nm) upon skin temperature and antidromic conduction latencies in human median nerve: relevance of radiant exposure. Lasers Surg Med. 1994;14:40–6. 129. Laakso E, Cramond T, Richardson C, Galligan J. Plasma ACTH and beta-endorphin levels in response to low-level laser therapy (LLLT) for myofascial trigger points. Laser Ther. 1994;6:133–42. 130. Laakso E e Cabot PJ. Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat. Photomed Laser Surg. 2005;23:32–5. 131. Aimbire F, Albertini R, Pacheco MT, Castro-Faria-Neto HC, Leonardo OS, Iversen W, et al. Low-level laser therapy induces dose-dependent reduction of TNFa levels in acute inflammation. Photomed Laser Surg. 2006;24:33–7. 132. Snyder-Mackler L e Bork CE. Effect of heliumneon laser irradiation on peripheral sensory nerve latency. Phys Ther. 1988; 68:223–5. 133. Maeda T. Morphological demonstration of low reactive laser therapeutic pain attenuation effect of the gallium aluminium arsenide diode laser. Laser Therapy. 1989;1:23–30. 134. Wesselmann U, Lin S, Rymer W. Effects of Q-switched Nd:YAG laser irradiation on neural impulse propagation: I. spinal cord. Physiol Chem Phys Med. 1991;23:67–80. 135. Wakabayashi H, Hamba M, Matsumoto K, Tachibana H. Effect of irradiation by semiconductor laser on responses evoked in trigeminal caudal neurons by tooth pulp stimulation. Lasers Surg Med. 1993;13:605–10. 136. Barberis G, Gamron S, Acevedo G, Cadile I, Juri H, Campana V, et al. In vitro synthesis of prostaglandin E2 by synovial tissue after helium-neon laser radiation in rheumatoid arthritis. J Clin Laser Med Surg. 1996;14:175-7. 137. Sakurai Y, Yamaguchi M, Abiko Y. Inhibitory effect of low-level laser irradiation on LPS-stimulated Prostaglandin E2 production and cyclooxygenase-2 in human gingival fibroblasts. Eur J Oral Sci. 2000;1081:29–34.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da Universidade Cruzeiro do Sulinstname:Universidade Cruzeiro do Sul (UNICSUL)instacron:UNICSULORIGINALStella Pelegrini.pdfStella Pelegrini.pdfDissertaçãoapplication/pdf1474812http://dev.siteworks.com.br:8080/jspui/bitstream/123456789/1142/1/Stella%20Pelegrini.pdfd7c0422c5e700282c98393ee8245f7e3MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://dev.siteworks.com.br:8080/jspui/bitstream/123456789/1142/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52123456789/11422020-12-01 11:05:58.773oai:repositorio.cruzeirodosul.edu.br:123456789/1142Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPRIhttps://repositorio.cruzeirodosul.edu.br/oai/requestmary.pela@unicid.edu.bropendoar:2020-12-01T14:05:58Repositório Institucional da Universidade Cruzeiro do Sul - Universidade Cruzeiro do Sul (UNICSUL)false
dc.title.pt_BR.fl_str_mv Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
title Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
spellingShingle Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
Pelegrini, Stella
FISIOTERAPIA E TERAPIA OCUPACIONAL
Terapia a laser
Medição da dor
Limiar da dor
Analgesia
title_short Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
title_full Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
title_fullStr Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
title_full_unstemmed Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
title_sort Efeito local e sistêmico do laser de baixa potência (830nm) no limiar de dor por pressão em indivíduos saudáveis: estudo prospectivo, controlado, randomizado
author Pelegrini, Stella
author_facet Pelegrini, Stella
author_role author
dc.contributor.advisor1.fl_str_mv Liebano, Richard Eloin
dc.contributor.advisor1ID.fl_str_mv https://orcid.org/0000-0003-4795-6723
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/1397951221512127
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/4639003464164800
dc.contributor.author.fl_str_mv Pelegrini, Stella
contributor_str_mv Liebano, Richard Eloin
dc.subject.cnpq.fl_str_mv FISIOTERAPIA E TERAPIA OCUPACIONAL
topic FISIOTERAPIA E TERAPIA OCUPACIONAL
Terapia a laser
Medição da dor
Limiar da dor
Analgesia
dc.subject.por.fl_str_mv Terapia a laser
Medição da dor
Limiar da dor
Analgesia
description Introdução: O laser de baixa potência (LBP) é utilizado como recurso terapêutico para controle da dor. Porém, ainda é questionado o seu real efeito como também a dosimetria mais eficaz para esse efeito analgésico. Objetivo: Avaliar o efeito local e sistêmico do LBP no limiar de dor por pressão em indivíduos saudáveis. Materiais e Métodos: 150 indivíduos distribuídos aleatoriamente em 5 grupos (n=30 por grupo): controle, laser placebo, 3J, 6J, 12J. Como instrumento para avaliar a dor foi utilizado algômetro de pressão em cinco tempos distintos. Na região da mão dominante do indivíduo foi realizado o laser e a algometria para verificar o efeito local e na região da perna dominante foi realizado somente a algometria para verificar efeito sistêmico do LBP. Resultados: Houve redução local do limiar de dor por pressão no grupo 3J em comparação com os grupos controle (p=0,0016) e placebo (p=0,004) e não houve alteração sistêmica do limiar de dor por pressão. Conclusão: O LBP quando utilizado com energia de 3J reduziu o limiar de dor por pressão local em indivíduos saudáveis, porém não houve alteração sistêmica
publishDate 2012
dc.date.issued.fl_str_mv 2012-03-03
dc.date.accessioned.fl_str_mv 2020-12-01T13:54:45Z
dc.date.available.fl_str_mv 2020-12-01T13:54:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://repositorio.cruzeirodosul.edu.br/handle/123456789/1142
url https://repositorio.cruzeirodosul.edu.br/handle/123456789/1142
dc.language.iso.fl_str_mv por
language por
dc.relation.references.pt_BR.fl_str_mv 1. International Association for the Study to Pain – IASP, 2010. Acesso em 10/04/2010 as 21h30 min. Disponível em http://www.iasp-pain.org. 2. Merkey H, Albe-Fessard DG, Bonica JJ, Carmon A, Dubner R, Kerr FWL, et al. Pain terms. A list with definitions and notes on usage. Recommended by IASP Subcommitte on Taxonomy. Pain. 1979;6(3):249-52. 3. Nes AG, Posso MB. Patients with moderate chemotherapy-induced mucositis: pain therapy using low intensity lasers. Int Nurs Rev. 2005; 52(1):68-72. 4. Moran F, Leonard T, Hawthorne S, Hughes CM, McCrum-Gardner E, Johnson MI, et al. Hypolgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensiy. J Pain. 2011;12(8):929-35. 5. Pantaleão MA, Laurino MF, Gallego NLG, Cabral CMN, Rakel B, Vance C, et al. Adjusting pulse amplitude during TENS application produces greater hypoalgesia. J Pain. 2010;12(5):581-90. 6. Johnson MI, Ghasala T. An investigation into the analgesic effect of different frequencies of the amplitude-modulated wave of interferencial current theraphy ob cold-induced pain in normal subjects. Arch Phys Med Rehabil. 2003;84:1387-94. 7. Sthephenson R, Walker EM. The analgesic effects of interferential current on cold-pressor pain in healthy subjects. A single blind trial of three IF current against sham IF and control. Arch Phys Theory and Prtice. 2003;19:99-107. 8. Fare JC, Nicolau RA. Clinical analysis of the effect of laser photobiomodulation (GaAs – 904nm) on temporomandibular joint dysfunction. Rev Bras Fisioter. 2008;12(1):37-42. 9. Beckerman H, Ble RA, Bouter LX, Cuyper HJ, Oostendorp RAB. The efficacy of laser therapy for musculoskeletal and skin disorders: a criteria-based meta-analysis of randomized clinical trials. Phys Ther. 1992;72(7):483-91. 10. Sooshtari SM, Badiee V, Taghizadeh SH, Grami MT. The effects of low level lser in clinical outcome and neurophysiological results of carpal tunnel syndrome. Electromyorg Clin Neurophysiol. 2008;48(5):229-31. 11. Chow RT, Johnson MI, Lopes-Martins RA, Bjordal JM. Efficacy of low-level laser therapy in the management of neck pin: a systematic review and meta-analysis of randomized placebo or active-treatment controlled trials. Lancet. 2009;374(9705):1897-908. 12. Lopes-Martins RA, Albertine R, Martins PSLL, Bjordal JM, Faria Neto HCC. Spontaneous effects of low-level laser therapy (650nm) in acute inflammatory mouse pleurisy induced by carrageenan. Photomed Laser Sugery. 2005;23(4):337-81. 13. Karu TI. Molecular mechanism of low-power lasertherapy. Lasers Life Sci. 1998;2:53-74. 14. Bolognani L, Majni G, Costato M, Milani M. ATPase and ATPsynthetase activity in myosin exposed to low power laser and pulsed electromagnetic fields. Biocelectrochem Bioenerg. 1993;32(2):155-64. 15. Colls JL. La terapia laser hoy. Barcelona: Centro Documentacion Laser de Meditec. 1986. 16. Peavy GM. Lasers and laser-tissue interaction. Vet Clin North Am Small Anim Pract. 2002;32(3):517-34. 17. Walker J. Relief from chronic pain by low laser irradiation. Neurosci Lett. 1983;43(2-3):339-44. 18. Herrero C. Los efectos terapeuticos. Bol Sociedad Español Láser Médico Quirúrgico. 1988;15(16):22-6. 19. Hansson TL. Infrared laser in the treatment of craniomandibular e disordrs, arthrogenous pain. J Prosthet Dent. 1989;61(5):614-7. 20. Ferreira DM, Zângaro RA, Villaverde AB, Cury Y, Frigo L, Piccol G, et al. Analgesic effect of He-Ne (632.8nm) low-level lasers therapy on acute inflammatory pain. Photomed Laser Surg. 2005;23(2):177-81. 21. Bjordal JM, Iversen JV, Aimbire F, Lopes-Martins RA. Low-level laser therapy in acute pain: a systematic review of possible mechanisms of action and clinical effects in randomized placebo-controlled trials. Photomed Lasers Surg. 2006;24(2):158-68. 22. Lievens PC. Effects of laser treatment on the lymphatic sysem and wound healing. J Eur Med Laser Associ. 1988;1(2):12. 23. Honmura A, Yanase M, Obata J, Haruki E. Therapeutic effect of Ga-Al-As diode laser irradiation on experimentally induced inflammation in rats. Lasers Surg Med. 1992;12(4):441-9. 24. Aimbire F, Albertine R, Magalhães RG, Lopes-Martins RA, Castro-Faria-Neto RA, Zângaro RA, et al. Effect of LLLT Ga-Al-As (685 nm) on LPS – induced inflammation of the airway and lung in the rat. Lasers Med Sci. 2005;20(1):11-20. 25. Albertini R, Aimbire F, Villaverde AB, Silva JÁ JR, Costa MS. Cox-2 mRNA expression decreases in the subplantar muscle of rat paw subjected to carraggenan-induced inflammation after low level laser therapy. Inflamm Res. 2007;56(6):228-9. 26. Correa F, Lopes Martins RA, Correa JC, Iversen VV, Joenson J, Bjordal JM. Low-level laser therapy (GAAS lambda = 904nm) reduces inflammatory all migration in mice with lipopolysaccharide-induced peritonitis. Photomed Laser Surg. 2007;25(4):245-9. 27. Boschi ES, Leite CE, Saciura VC, Caberlan E, Leenardelli A, Bitencourt S, et al. Anti-inflammatory effects of low-level laser therapy (660nm) in the early phase in carrageean-induced pleurisy in rat. Lasers Surg Med. 2008;40(7):500-8. 28. Morais NC, Barbosa AM, Vale ML, Villaverde AB, De Lima CJ, Cogo JC, et al. Anti-inflammatory effect of low-level laser and ligth-emitting diode in zymosan-induced arthritis. Photomed Laser Surg. 2010;28(2):227-32. 29. Abergel RP. Increased wound-healing rate in pig skin treated by Helium-Neon laser. Int Soc Optical Engin Proces. 1988:6–10. 30. Bihari, J & Mester, AR. The biostimulative effect of low level laser therapy on longstanding crural ulcers using Helium Neon laser, Helium Neon laser plus infrared lasers, and noncoherent light: preliminary report of a randomised double blind comparative study. Laser Ther. 1989;1(2):97. 31. Kucerová H, Dostálavá T, Himmeová L, Bartová J, Mazánek J. Low-level laser therapy after molar extraction. J Clin Laser Med Surg. 2000;18(6):309-15. 32. Benedicenti, A. La Valutazione Dell Effecto Del la Luce Laser 904nm Nella Circolazione Ematica in Vivo. Langa Grafica, Atlate di laserterapia Gênova. 1983:71–83. 33. Kubota, J & Ohshiro, T. The effects of diode laser low reactive level laser therapy (LLLT) on flap survival in a rat model. Laser Ther. 1989;1(3):127. 34. Karu T. Photobiology of low-power lasers effects. Health Phys. 1989;56(5):691-704. 35. Kitchen SS e Partridge CJ. A review of low level laser therapy. Physiother. 1991;77(3):161-8. 36. Bjordal JM, Lopes-Martins RA, Joensen J, Couppe C, Ljunggren AE, Stergioulos A. A systematic review with procedural assessments and meta-analysis of low level laser therapy in lateral elbow tendinopathy (tennis elbow). BMC Musculoskelet Disord. 2008;29:9-75. 37. Basford JR, Hallman HO, Matsumoto JY, Moyer SK, Buss JM, Baxter GD. Effects of 830nm continous wave laser diode irradiation on median nerve function in normal subjects. Lasers Surg Med. 1993;13(6):597-604. 38. Hadian M e Moghagdam, B. The effects of low power laser on electrophysiological parameters of sural nerve in normal subjects: a comparison between 670 and 780nm wavelengths. Acta Med Iran. 2003;41:138–42. 39. Laakson L, Richardson C, Cramond T. Pain scores and plasma beta-endorphin and ACTH levels in response to low level laser therapy – a possible mechanism of action. Presented at the 12th International Congress on Physical Therapy, Washington, DC, 1995. 40. Hagiwara S, Iwasaka H, Hasegawa A, Noguchi T. Pre-irradiation of blood by gallium aluminum arsenide (830 nm) low-level laser enhances peripheral endogenous opioid analgesia in rats. Anesth Analg. 2008;107(3):1058–63. 41. Ceylan Y, Hizmetli S, Silig Y. The effects of infrared laser and medical treatments on pain and serotonin degradation products in patients with myofascial pain syndrome. A controlled trial. Rheumatol Int. 2004;24:260-3. 42. Mackler LS, Barry AJ, Perkins AI, Soucek MD. Effects of helium-neon laser irradiation on skin resistence and pain in patients with trigger points in the neck or back. Phys Ther. 1989;69(5):336-41. 43. Gur A, Karakoc KN, Cqevie R, Sarac J, Demir E. Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo-controlled trial. Laser Med Sci. 2002;17:57-61. 44. Sharma R, Thukral A, Kumar S, Bhargava SK. Effect of low level lasers in the Quervains tenosynovitis: Prospective study ultrasonographyc assessment. Physiother. 2002;88(12):730-4 45. Altan L, Bingo I, Aykac M, Yurtkuran M. Investigation of the effect of GaAs laser therapy on cervical myofascial pain syndrome. Rheumatol Int.2005;25:23-7. 46. Basford JR, Malanga GA, Krause DA, Harmsen WS. A randomized controlled evaluation of low-intensity laser therapy: plantar fasciitis. Arch Phys Med Rehabil. 1998;79:249-54. 47. Brosseau L, Wells G, Marchand S, Gaboury I, Stokes B, Morin M et al. Randomized controlled trial on low level laser therapy (LLLT) in the treatment of osteoarthritis (OA) of the hand. Laser Surg Med. 2005;36:210-9. 48. Rochkind S, Rousso M, Nissan M, Villaverde M, Barr-Nea L, Rees DG. Systemic effects of low-power laser irradiation on the peripheral and central nervous system, cutaneous wound, and burns. Lasers Surg Med. 1989;9:174-82. 49. Sandoval-Ortiz MC, Mattiello-Rosa SM, Soares EG, Parizotto NA. Influência do laser de baixa potência nos níveis das proteínas plasmáticas de coelhos. Rev Bras Fisiot. 2003;7(3):187-94. 50. Hopkins JT, McLoda TA, Seegmiller JG, Baxter GD. Low-level laser therapy facilitates superficial wound healing in humans: A triple-blind, sham-controlled study. J Athl Train. 2004;39(3):223-9. 51. Ferreira MC, Brito VN, Gameiro J, Costa MRS, Vasconcellos ECS, Cruz-Hofling MAC. Effects of HeNe laser irradiation on experimental paracoccidioidomycotic lesions. J Photochem Photob B: Biol. 2006;84:141-9. 52. Hawkins D, Abrahamse H. Phototherapy – A treatment modality for wound healing and pain relief. J Biomed Res. 2007;10:99-109. 53. Rodrigo SM, Cunha A, Pozza DH, Blaya DS, Moraes JF, Weber JBB, et al. Analysis of the systemic effect of red and infrared laser therapy on wound repair. Photomed Laser Surg. 2009;27(6):929-35. 54. Schuhfried M, Korpan V, Silig Y. Helium-Neon laser irradiation: effect on the experimental pain threshold. Lasers Med Sci. 2000;15:169-73. 55. Doing GS e Simpson F. Randomization and allocation concealment: A pratical guide for researches. J Crit Care. 2005;20:187-91. 56. Scales DC, Adhikari NK. Maintaining allocation concealment: Following your SNOSE. J Crit Care. 2005;20:191-3. 57. Cowan S, McKenna J, McCrum-Gardner E, Johnson MI, Sluka KA, Walsh DM: An investigation of the hypoalgesic effectsof TENS delivered by a glove electrode. J Pain 2009; 10: 694-701. 58. Frey Law LA, Sluka Ka, McMullen T, Lee J, Nielsen LA, Nielsen TG. Acidic buffer induced muscle pain evokes refered pain and mechanical hyperalgesia in humans. Pain. 2008;140(2):254-64. 59. Nie HL, Nielsen TG, Nielsen LA. Spatial and temporal summation of pain evoked by mechanical pressure stimulation. Eur J of Pain. 2009;13:592-9. 60. Nielsen MM, Mortensen A, Sorensen JK, Simonsen O, Nielsen TG. Reduction of experimental muscle pain by passive physiological movements. Manual Therapy. 2009;14:101-9. 61. Chesterton LS, Barlas P, Foster NE, Lundeberg t, Wright CC, Baxter GD. Sensory Stimulation (TENS): effects of parameter manipulation on mechanical pain thresholds in healthy human subjects. Pain. 2002;99:253-62. 62. Chesterton LS, Foster NE, Wright CC, Baxter GD, Barlas P. Effects of TENS frequency, intensity and stimulation site parameter manipulation on pressure pain thresholds in healthy human subjects. Pain. 2003;106:73-80. 63. Rakel B, Cooper N, Adams HJ, Messer BR, Frey Law LA, Dannen DR, et al. A new transient sham TENS device allows for investigator blinding while delivering a true placebo treatment. J Pain 2010; 11:230-8. 64. Liebano RE, Rakel B, Vance CGT, Walsh DM, Sluka KA. An investigation of development of analgesic tolerance to TENS in humans. Pain. 2011;152(2):335-42. 65. Palmer ST, Steedman W, Martin DJ, Ravey J. Alteration of interferential current and transcutaneous electrical nerve stimulation frequency: effects on nerve excitation. Arch Phys Med Rehabil. 1999;80(9):1065-71. 66. Alves-Guerreiro J, Noble JG, Lowe AS, Walsh DM. The effect of three electrotherapeutic modalities upon peripheral nerve conduction and mechanical pain threshold. Clin Physiol. 2001; 21(6):704-11. 67. Minder PM, Noble JG, Alves-Guerreiro J, Hill ID, Lowe AS, Walsh DM, et al. Interferential therapy: lack of effect upon experimentally induced delayed onset muscle soreness. Clin Physiol Funct Imaging. 2002; 22(5):339-47. 68. Lowe As, McDowell BC, Walsh DM, Baxter GD, Allen JM. Failure to demonstrate any hypoalgesic effect of low intensity laser irradiation (830nm) of Erb’s point upon experimental ischaemic pain in human. Laser Surg Med. 1997;20:69-76. 69. Ferrante FM, Bearn L, Rothrock R, King L. Evidence against trigger point injection technique for the treatment of cervicothoracic myofascial pain with Botulinum Toxin Type A. Anesthesiology. 2005;103: 377-83. 70. Fischer AA. Pressure algometry over normal muscles. Standard values, validity and reproducibility of pressure threshold. Pain 1987;30(1):115–26. 71. Mokhtar B, Callaghan G, Baxter GD, Bell AJ, Allen JM. The possible significance of pulse repetition rate in lasermediated analgesia: A double blind placebo controlled investigation using experimental ischaemic pain. Proceedings of the Second Meeting of the International Laser Therapy Association. 1992:62. 72. Johnson MI, Tabasam G. An investigation into the analgesic effects of interferential currents and transcutaneous electrical nerve stimulation on experimentally induced ischemic pain in otherwise pain-free volunteers. Phys Ther. 2003;83(3):208-23. 73. Sumikura H, Andersen OK, Drewes AM, Arendt-Nielsen L. A comparison of hyperalgesia and nerogenic inflammation induced by melittin and capsaicin in humans. Neurosci Lett. 2003;337(3):147-50. 74. Drewes AM, Schipper KP, Dimcevski G, Petersen P, Gregersen H, Funch-Jensen P, Arendt-Nielsen L. Gut pain and hyperalgesia induced by capsaicin: a human experimental model. Pain. 2003;104(1-2):333-41. 75. Frot M, Feine JS, Bushnell MC. Sex differences in pain perception and anxiety. A psychophysical study with topical capsaicin. Pain. 2004;108(3):230-6. 76. Nussbaum EL e Dawnes L. Reliability of clinical pressure-pain algometric measurements obtained on consecutive days. Phys Ther. 1998;78(2):160-9. 77. Ogimoto T, Ogawa T, Sumiyoshi K, Matsuka Y, Koyono K. Pressure pain threshold determination in the oral mucosa: validity and reliability. J Oral Rehabil. 2002;29:620-6. 78. Farasy A, Meusen R. Pressure pain threshold in healthy subjects: influence of physical activity, history of low back pain factors and the use of endermology as a placebo-like treatment . J of Bodyw Mov Ther. 2003;7:53-61. 79. Prushansky T, Dvir Z, Defrin-Assa R. Reproducibility indices applied to cervical pressure pain threshold measurements in healthy subjects. Clinl J Pain. 2004;20:341-7. 80. Ylinen J, Takala EP, Kautianien H, Nykanen A, Pohyolainen N, et al. Effect of long-term neck muscle training on pressure pain threshold: a randomized controlled trial. Eur J Pain. 2005;9:673-81. 81. Cathcart S, Pritchard D. Reliability of pain threshold measurement in young adults. J Headache Pain. 2006;721-6. 82. Ylinen J, Nykãnen M, Kautiainen H, Hãkkinen A. Evaluation of repeatability of pressure algometry on the neck muscles for clinical use. Man Ther, 2007;12(2):192-7. 83. Chesterton LS, Sim J, Wright CC, Foster NE. Interrater reliability of algometry in measuring pressure pain threshold in healthy humans, using multiple raters. Clin J Pain. 2007;23(9):760-6. 84. Kinser AM, Sands WA, Stone MH. Reliability and validity of a pressure algometer. J Strength Cond Res. 2009;23(1):312-4. 85. Marques AP, Ferreira EAG, Matsutani LA, Pereira CAB, Assumpção A. Quantifying pain threshold and quality of life of fibromyalgia patients. Clin Rheumatol. 2005;24:266-71. 86. Egan TD, Kern SE, Muir KT, White JL. Remifentanil by bolus injection: a safety, pharmacokinetic, pharmacodynamic, and age effect investigation in human volunteers. Br J Anaesth. 2004;92(3):335-43. 87. Kern SE, Xie G, White JL, Egan TD. Opioid-hypnotic synergi. A response surface analyses of propofal-remifentanil pharmacodynamic interaction in volunteers. Anesthesiology. 2004;100:1373-81. 88. Tucker AP, Kim YI, Nadson R, Goodchild CS. Investigation of the patentiation of the analgesic effects of fentanyl by ketamine in humans: a double-blinded, randomized, placebo controlled, crossover study of experimental pain. BMC Anesthesiol. 2005;5(1):2. 89. Edwards J e Knowus N. Superficial dry needing and active stretching in the treatment of myofascial pain – A randomised controlled trial. Acup In Med. 2003;21(3):80-6. 90. Hou CR, Tsai LC, Cheng KF, Chung KC, Kong CZ. Immediate effects of various physical therapeutic modalities on cervical myofascial pain and trigger-point sensitivity. Arch Phys Med Rehabil. 2002;83:1406-14. 91. Baraniuk JN, Whalen G, Cunningham J, Clauw IJ. Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back pain. BMC Musculoskel Disord. 2004;5:48. 92. Poletto PR, Coury GHJC, Walsh IAP, Mattielo-Rosa SM. Correlação entre métodos de auto-relato e testes provocativos de avaliação da dor em indivíduos portadores de distúrbios osteomusculares relacionados ao trabalho. Rev Bras Fisioter. 2004;8(3):223-9. 93. Pinheiro AL, Cavalcanti ET, Pinheiro TI, Alves MJ, Manzi CT. Low-level laser therapy in the management of disorders of the maxillofacial region. J Clin Laser Med Surg. 1998;15:181–3. 94. Kreisler M, AI Haj H, Daublander M, Gotz H, Duschner H, Willershausen B, et al. Effect of diode laser irradiation on root surfaces in vitro. J Clin Laser Med Surg. 2002;20(2):63-9. 95. Chavantes MC. Laser em bio-medicina. São Paulo: Atheneu; 2009. 96. Baxter D. Laserterapia de baixa intensidade. In: Kitchen S. Eletroterapia prática baseada em evidências. São Paulo: 11ª ed; 2003. p. 171-89. 97. Baxter G, Allen J, Bell A. The effect of low energy density laser irradiation upon human median nerve conduction latencies. J Physiol. 1990;435:63. 98. Baxter GD, Allen AJ, Bell J, Ravey J, Diamantopoulos C. Effect of laser (830 nm) upon conduction in the median nerve. Laser Surg Med. 1991;3:79. 99. Toya S, Motegi M, Inomata K, Ohshiro T, Maeda T. Report on a computer-randomised double blind clinical trial to determine the effectiveness of the GaAlAs (830nm) diode laser for pain attenuation in selected pain groups. Laser Ther. 1994;6:143–8. 100. Baxter GC, Walsh DM., Allen JM, Lowe AS, Bell AJ. Effects of low intensity infrared laser irradiation upon conduction in the human median nerve in vivo. Exp Physiol. 1994;79: 227–34. 101. Bartllet W, Qyillen W, Gonzales J. Effect of gallium-aluminum-arsenid trple-diode laser on median nerve latency in human subjects. J Sport Rehabil. 1999;8:99-108. 102. Cambier D, Blom K, Witvrouw E, Ollevier G, Muynck M, Vanderstraeten G. The influence of low intensity infrared laser irradiation on conduction characteristics of peripheral nerve: a randomised, controlled, double blind study on the sural nerve. Lasers Med Sci. 2000;15:195-200. 103. Walsh DM, Baxter GD, Allen JM. Lack of effect of pulsed low-intensity infrared (820nm) laser irradiation on nerve conduction in the human superficial radical nerve. Lasers Surg Med. 2000;26:485-90. 104. Özdemir F, Birtane M, Kokino S. The clinical efficacy of low-power laser therapy on pain and function in cervical osteoarthritis. Clin Rheumatol. 2001;20:181–4. 105. Seidel U, Uhlemann C. A randomised controlled double-blind trial comparing dose laser therapy on acupuncture points and acupuncture for chronic cervical syndrome. Dtsch Z Akupunktur. 2002;45:258–69. 106. Chow RT, Barnsley LB, Heller GZ, Siddall PJ. A pilot study of low-power laser therapy in the management of chronic neck pain. J Musculoskelet. Pain 2004;12:71-81. 107. Gur A, Sarac AJ, Cevik R, Altindag O, Sarac S. Efficacy of 904nm gallium arsenide low level laser therapy in the management of chronic myofascial pain in the neck: a double-blind and randomized-control. Lasers Surg Med. 2004;35:229–35. 108. Bjordal JM, Lopes-Martins RA, Iversen W. A randomised, placebo controlled Trial of low level laser therapy for activated Achilles Tendinitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations. Br J Sports Med. 2005;40(1):76-80. 109. Chow, R.T., Barnsley, L.B., and Heller, G.Z. The effect of 300mW, 830nm laser on chronic neck pain: a double-blind, randomized, placebo-controlled study. Pain. 2006;124:201–10. 110. Dundar E, Evcik D, Samli F, Pusak H, Kavuncu V. The effect of gallium arsenide aluminum laser therapy in the management of cervical myofascial pain syndrome: a double blind, placebo-controlled. Clin Rheumatol 2006;26:930–4. 111. Kato MT, Kogawa EM, Santos CN, Conti PCR. TENS and low-level laser therapy in the management of temporomandibular disorders. J. Appl. Oral. Sci. 2006;14(2):130-5. 112. Chow R, David M, Armati P. 830-nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830-nm laser. J Peripher Nerv Syst. 2007;12:28–39. 113. Konstantinovic LM, Kanjuh ZM, Milovanovic AN, Cutovic MR, Djuovic AG, Savic VG, et al. Acute low back pain with radiculopathy: a double-blind, randomized, placebo-controlled study. Photomed Laser Surg. 2009;1-8. 114. Chow R, Armat P, Laakso EL, Bjordal JM, Baxter GD. Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: a systematic review. Photomedicine and Laser Surgery. 2011:1-17. 115. Kramer JF, Sandrin M. Effect of low-power laser and white light on sensory conduction rate of the superficial radial nerve. Physiother Can. 1993;45:165–70. 116. Ilbuldu E, Cakmak A, Disci R, Aydin R. Comparison of laser, dry needling and placebo laser treatments in myofascial pain syndrome. Photomed Laser Surg. 2004; 22:306–11. 117. Aigner N, Fialka C, Radda C, Vecsei V. Adjuvant laser acupuncture in the treatment of whiplash injuries: a prospective, randomized placebo-controlled trial. Wien Klin Wochenschr. 2006;118:95–9. 118. Karu T. Primary and secondary mechanisms of action of visible to near-IR radiation on cell. J Photochem Photobiol B. 1999;49(1):1-7. 119. Low J, Reed A. Eletroterapia explicada: princípios e prática. 3ª ed. São Paulo: Manole; 2001. 120. Kosek E, Ekholm J, Hansson P. Pressure pain thresholds in different tissues in one body region. The influence of skin sensitivity in pressure algometry. Scand J Rehabil Med. 1999;31(2):89–93. 121. Leffler AS, Hansson P, Kosek E. Somatosensory perception in a remote pain-free area and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from long-term trapezius myalgia. Eur J Pain. 2002;6(2):149–159 122. Leffler AS, Hansson P, Kosek E. Somatosensory perception in patients suffering from long-term trapezius myalgia at the site overlying the most painful part of the muscle and in an area of pain referral. Eur J Pain. 2003;7(3):267–276 123. Bjordal J, Couppe C, Chow R, Tuner J, Ljunggren A. A systematic review of low level laser therapy with location-specific doses for pain from chronic joint disorders. Aust J Physiother. 2003;49:107–16. 124. Irvine, J Chong SL, Amrjani N, Chan KM. Double-blind randomized controlled trial of LLLT in carpal tunnel syndrome. Muscle Nerve. 2004;30:182–7. 125. Gross AR, Goldsmith C, Howing JL, Haines T, Peloso P, Aker P, et al. Conservative management of mechanical neck disorders: a systematic review. J Rheumatol. 2007;34(5):1083-102. 126. Bjordal J, Johnson MI, Lopes-Martins RA, Bogen B, Chow R, Ljunggren AE. Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomized placebo-controlled trials. BMC Musculoskelet Disord. 2007;8(51). 127. Bjordal J, Couppe C, Ljunggren AE. Low-level laser therapy for tendinopathy: evidence of a dose-response pattern. Phys Ther. 2001;6:91-9. 128. Lowe A, Baxter G, Walsh D, Allen J. Effect of low-intensity laser irradiation (830 nm) upon skin temperature and antidromic conduction latencies in human median nerve: relevance of radiant exposure. Lasers Surg Med. 1994;14:40–6. 129. Laakso E, Cramond T, Richardson C, Galligan J. Plasma ACTH and beta-endorphin levels in response to low-level laser therapy (LLLT) for myofascial trigger points. Laser Ther. 1994;6:133–42. 130. Laakso E e Cabot PJ. Nociceptive scores and endorphin-containing cells reduced by low-level laser therapy (LLLT) in inflamed paws of Wistar rat. Photomed Laser Surg. 2005;23:32–5. 131. Aimbire F, Albertini R, Pacheco MT, Castro-Faria-Neto HC, Leonardo OS, Iversen W, et al. Low-level laser therapy induces dose-dependent reduction of TNFa levels in acute inflammation. Photomed Laser Surg. 2006;24:33–7. 132. Snyder-Mackler L e Bork CE. Effect of heliumneon laser irradiation on peripheral sensory nerve latency. Phys Ther. 1988; 68:223–5. 133. Maeda T. Morphological demonstration of low reactive laser therapeutic pain attenuation effect of the gallium aluminium arsenide diode laser. Laser Therapy. 1989;1:23–30. 134. Wesselmann U, Lin S, Rymer W. Effects of Q-switched Nd:YAG laser irradiation on neural impulse propagation: I. spinal cord. Physiol Chem Phys Med. 1991;23:67–80. 135. Wakabayashi H, Hamba M, Matsumoto K, Tachibana H. Effect of irradiation by semiconductor laser on responses evoked in trigeminal caudal neurons by tooth pulp stimulation. Lasers Surg Med. 1993;13:605–10. 136. Barberis G, Gamron S, Acevedo G, Cadile I, Juri H, Campana V, et al. In vitro synthesis of prostaglandin E2 by synovial tissue after helium-neon laser radiation in rheumatoid arthritis. J Clin Laser Med Surg. 1996;14:175-7. 137. Sakurai Y, Yamaguchi M, Abiko Y. Inhibitory effect of low-level laser irradiation on LPS-stimulated Prostaglandin E2 production and cyclooxygenase-2 in human gingival fibroblasts. Eur J Oral Sci. 2000;1081:29–34.
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