Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado

Detalhes bibliográficos
Ano de defesa: 2018
Autor(a) principal: Ferrari, Wesley Fernando lattes
Orientador(a): Camilotti , Veridiana lattes
Banca de defesa: Camilotti , Veridiana lattes, Bosquiroli , Virginia lattes, Pini , Núbia Inocencya Pavesi lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Estadual do Oeste do Paraná
Cascavel
Programa de Pós-Graduação: Programa de Pós-Graduação em Odontologia
Departamento: Centro de Ciências Biológicas e da Saúde
País: Brasil
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://tede.unioeste.br/handle/tede/4142
Resumo: Aims: Evaluate the efficacy of dental bleaching and the tooth sensitivity during and after the procedure using a Potassium Nitrate and Sodium Fluoride based desensitizer gel, with or without Chitosan microparticles. Methods and Materials: Forty-two patients with a minimum A2 degree of saturation were selected, divided into two groups (n = 21): DKF - Potassium Nitrate with Sodium Fluoride and DKF CHI - Potassium Nitrate with Sodium Fluoride plus Chitosan microparticles. Dental bleaching was performed in the upper arch, using 35% Hydrogen Peroxide in a single session, with three applications of 15 minutes each. The desensitizing gel was applied before the treatment and remained on the enamel for 10 minutes in both groups. Tooth sensitivity (TS) was recorded by participants by means of scores while the bleaching gel was in contact with the teeth (5, 10, 15, 20, 25, 30, 35, 40 and 45 minutes), as well as 1, 24 and 48 hours after application. The shade evaluation was performed at baseline and seven days after bleaching. TS was evaluated by the Mann-Whitney test (p <0.05). The Kruskal-Wallis test (p <0.05) was used to assess the degree of bleaching. Results: At the 40, 45 minute and 1 hour evaluation periods, the sensitivity levels of the DFK CHI group were significantly lower in relation to the DKF group. Regarding the shade level, there was no significant interference in the outcome for both groups evaluated. Conclusions: the addition of chitosan microparticles to the desensitizing agent decreases sensitivity during and after tooth bleaching without interfering on the bleaching efficacy.Clinical relevance: the use of a desensitizing agent with chitosan microparticles prior to dental bleaching may decrease dentin sensitivity, which is the most common side effect associated with tooth bleaching.
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spelling Camilotti , Veridianahttp://lattes.cnpq.br/9340494276264996Camilotti , Veridianahttp://lattes.cnpq.br/9340494276264996Bosquiroli , Virginiahttp://lattes.cnpq.br/1099293451762462Pini , Núbia Inocencya Pavesihttp://lattes.cnpq.br/0798226450922503http://lattes.cnpq.br/6805114132326224Ferrari, Wesley Fernando2019-03-12T21:37:08Z2018-03-23FERRARI, Wesley Fernando. Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado. 2018. 33 f. Dissertação( Mestrado em Odontologia) - Universidade Estadual do Oeste do Paraná, Cascavel, 2018.http://tede.unioeste.br/handle/tede/4142Aims: Evaluate the efficacy of dental bleaching and the tooth sensitivity during and after the procedure using a Potassium Nitrate and Sodium Fluoride based desensitizer gel, with or without Chitosan microparticles. Methods and Materials: Forty-two patients with a minimum A2 degree of saturation were selected, divided into two groups (n = 21): DKF - Potassium Nitrate with Sodium Fluoride and DKF CHI - Potassium Nitrate with Sodium Fluoride plus Chitosan microparticles. Dental bleaching was performed in the upper arch, using 35% Hydrogen Peroxide in a single session, with three applications of 15 minutes each. The desensitizing gel was applied before the treatment and remained on the enamel for 10 minutes in both groups. Tooth sensitivity (TS) was recorded by participants by means of scores while the bleaching gel was in contact with the teeth (5, 10, 15, 20, 25, 30, 35, 40 and 45 minutes), as well as 1, 24 and 48 hours after application. The shade evaluation was performed at baseline and seven days after bleaching. TS was evaluated by the Mann-Whitney test (p <0.05). The Kruskal-Wallis test (p <0.05) was used to assess the degree of bleaching. Results: At the 40, 45 minute and 1 hour evaluation periods, the sensitivity levels of the DFK CHI group were significantly lower in relation to the DKF group. Regarding the shade level, there was no significant interference in the outcome for both groups evaluated. Conclusions: the addition of chitosan microparticles to the desensitizing agent decreases sensitivity during and after tooth bleaching without interfering on the bleaching efficacy.Clinical relevance: the use of a desensitizing agent with chitosan microparticles prior to dental bleaching may decrease dentin sensitivity, which is the most common side effect associated with tooth bleaching.Objetivos: avaliar a efetividade do clareamento dental profissional e a intensidade da sensibilidade durante e após o clareamento, utilizando um dessensibilizante à base de Nitrato de Potássio e Fluoreto de Sódio, acrescido ou não de micropartículas de Quitosana. Metodologia: foram selecionados 42 pacientes com grau de saturação dental mínima A2, divididos em dois grupos (n=21): DKF – Nitrato de Potássio com Fluoreto de Sódio e DKF QUI – Nitrato de Potássio com Fluoreto de Sódio acrescido de micropartículas de Quitosana. O clareamento foi realizado na arcada superior, com o uso de Peróxido de Hidrogênio a 35% em sessão única, com três aplicações de 15 minutos cada. O gel dessensibilizante foi aplicado previamente ao tratamento e permaneceu sobre o esmalte por 10 minutos, em ambos os grupos. O grau de sensibilidade (GS) foi anotado pelos pacientes por meio de escores, durante o tempo em que o gel clareador esteve em contato com os dentes (5, 10, 15, 20, 25, 30, 35, 40 e 45 minutos), assim como 1, 24 e 48 horas após a aplicação. O grau de saturação da cor foi avaliado no início e sete dias depois do clareamento. O GS foi avaliado pelo teste de Mann- Whitney (p<0.05). Para a avaliação do grau de clareamento, foi aplicado o teste de Kruskal- Wallis (p<0.05). Resultados: nos períodos de avaliação de 40, 45 minutos e 1 hora, os níveis de sensibilidade do grupo DFK QUI foram significativamente menores em relação ao grupo DKF. No que se refere ao grau de clareamento, não houve interferência significativa no resultado para ambos os grupos avaliados. Conclusões: a adição de micropartículas de Quitosana ao agente dessensibilizante diminui a sensibilidade durante e após o clareamento dental sem interferir no grau de clareamento.Relevância clínica: o uso prévio de um agente dessensibilizante com micropartículas de Quitosana pode diminuir a sensibilidade dentinária, que é o efeito colateral mais comum associado ao clareamento dental.Submitted by Edineia Teixeira (edineia.teixeira@unioeste.br) on 2019-03-12T21:37:08Z No. of bitstreams: 2 Wesley_Ferrari_2018.pdf: 5292494 bytes, checksum: 80e420551cea7ffdde2bfbfeff0d10eb (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2019-03-12T21:37:08Z (GMT). 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dc.title.por.fl_str_mv Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
dc.title.alternative.eng.fl_str_mv Efficacy of an experimental desensitizing gel: double-blind, controlled and randomized clinical trial
title Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
spellingShingle Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
Ferrari, Wesley Fernando
Clareamento dental
Sensibilidade da dentina
Quitosana
Tooth Bleaching
Dentin Sensitivity
Chitosan
CIENCIAS DA SAUDE::ODONTOLOGIA
title_short Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
title_full Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
title_fullStr Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
title_full_unstemmed Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
title_sort Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado
author Ferrari, Wesley Fernando
author_facet Ferrari, Wesley Fernando
author_role author
dc.contributor.advisor1.fl_str_mv Camilotti , Veridiana
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/9340494276264996
dc.contributor.referee1.fl_str_mv Camilotti , Veridiana
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/9340494276264996
dc.contributor.referee2.fl_str_mv Bosquiroli , Virginia
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/1099293451762462
dc.contributor.referee3.fl_str_mv Pini , Núbia Inocencya Pavesi
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/0798226450922503
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/6805114132326224
dc.contributor.author.fl_str_mv Ferrari, Wesley Fernando
contributor_str_mv Camilotti , Veridiana
Camilotti , Veridiana
Bosquiroli , Virginia
Pini , Núbia Inocencya Pavesi
dc.subject.por.fl_str_mv Clareamento dental
Sensibilidade da dentina
Quitosana
topic Clareamento dental
Sensibilidade da dentina
Quitosana
Tooth Bleaching
Dentin Sensitivity
Chitosan
CIENCIAS DA SAUDE::ODONTOLOGIA
dc.subject.eng.fl_str_mv Tooth Bleaching
Dentin Sensitivity
Chitosan
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE::ODONTOLOGIA
description Aims: Evaluate the efficacy of dental bleaching and the tooth sensitivity during and after the procedure using a Potassium Nitrate and Sodium Fluoride based desensitizer gel, with or without Chitosan microparticles. Methods and Materials: Forty-two patients with a minimum A2 degree of saturation were selected, divided into two groups (n = 21): DKF - Potassium Nitrate with Sodium Fluoride and DKF CHI - Potassium Nitrate with Sodium Fluoride plus Chitosan microparticles. Dental bleaching was performed in the upper arch, using 35% Hydrogen Peroxide in a single session, with three applications of 15 minutes each. The desensitizing gel was applied before the treatment and remained on the enamel for 10 minutes in both groups. Tooth sensitivity (TS) was recorded by participants by means of scores while the bleaching gel was in contact with the teeth (5, 10, 15, 20, 25, 30, 35, 40 and 45 minutes), as well as 1, 24 and 48 hours after application. The shade evaluation was performed at baseline and seven days after bleaching. TS was evaluated by the Mann-Whitney test (p <0.05). The Kruskal-Wallis test (p <0.05) was used to assess the degree of bleaching. Results: At the 40, 45 minute and 1 hour evaluation periods, the sensitivity levels of the DFK CHI group were significantly lower in relation to the DKF group. Regarding the shade level, there was no significant interference in the outcome for both groups evaluated. Conclusions: the addition of chitosan microparticles to the desensitizing agent decreases sensitivity during and after tooth bleaching without interfering on the bleaching efficacy.Clinical relevance: the use of a desensitizing agent with chitosan microparticles prior to dental bleaching may decrease dentin sensitivity, which is the most common side effect associated with tooth bleaching.
publishDate 2018
dc.date.issued.fl_str_mv 2018-03-23
dc.date.accessioned.fl_str_mv 2019-03-12T21:37:08Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv FERRARI, Wesley Fernando. Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado. 2018. 33 f. Dissertação( Mestrado em Odontologia) - Universidade Estadual do Oeste do Paraná, Cascavel, 2018.
dc.identifier.uri.fl_str_mv http://tede.unioeste.br/handle/tede/4142
identifier_str_mv FERRARI, Wesley Fernando. Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado. 2018. 33 f. Dissertação( Mestrado em Odontologia) - Universidade Estadual do Oeste do Paraná, Cascavel, 2018.
url http://tede.unioeste.br/handle/tede/4142
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dc.publisher.none.fl_str_mv Universidade Estadual do Oeste do Paraná
Cascavel
dc.publisher.program.fl_str_mv Programa de Pós-Graduação em Odontologia
dc.publisher.initials.fl_str_mv UNIOESTE
dc.publisher.country.fl_str_mv Brasil
dc.publisher.department.fl_str_mv Centro de Ciências Biológicas e da Saúde
publisher.none.fl_str_mv Universidade Estadual do Oeste do Paraná
Cascavel
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