Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19
Ano de defesa: | 2022 |
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Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , , , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade Estadual do Oeste do Paraná
Francisco Beltrão |
Programa de Pós-Graduação: |
Programa de Pós-Graduação em Ciências Aplicadas à Saúde
|
Departamento: |
Centro de Ciências da Saúde
|
País: |
Brasil
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | https://tede.unioeste.br/handle/tede/6499 |
Resumo: | COVID-19 is an acute respiratory disease caused by SARS-CoV-2 virus infection, which can cause severe hypoxemic respiratory failure, complications, and deaths, especially in the population with chronic health conditions. The mechanisms by which obesity may increase the severity of COVID-19 include physical mechanisms, chronic inflammation, and impaired immune function. In addition, high body mass index is a risk factor for several medical conditions that have been suggested to increase the risk of COVID-19 severity. Objective: to analyze the association between body mass index and clinical outcomes of confirmed cases of COVID-19. Methodology: Cross-sectional study, with data collection from medical records, conducted from March 2020 to December 2021. The records of medical records, biochemical and imaging tests of patients hospitalized with COVID-19 in three hospitals in the city of Francisco Beltrão (PR) were analyzed. The variables analyzed were nutritional diagnosis, age, gender, need for ICU admission, comorbidities, days of hospitalization, complications, laboratory tests and outcome. The inclusion criteria for the study were, hospitalized patients with diagnosis for COVID-19, with presence of nutritional diagnosis reported. Results: In the year 2020, 292 medical records were analyzed and in the year 2021 there were 860 medical records. Of these, only 413 had nutritional diagnosis, thus being included in this study. Were classified as normal weight 78 (18.9%), overweight 153 (37%), and obese 182 (44.1%) participants. The highest prevalence of obesity was found in females (52.5%), patients with diabetes (27.6%), patients with impaired general condition (67.9%), who presented pulmonary complications (54.5%) and arrhythmias (23%). The mean age found in obese patients was younger (55.54) compared to those classified as overweight (59.08) and normal (62.51). It was observed that the higher the BMI the lower were the values found for age (rho = -0.190), leukocytes (rho = -0.109), urea (rho = -0.145) and D-dimer (rho = -0.155). Conclusion: This study provides evidence that overweight and/or obesity then associated with a worse clinical picture during hospitalization of patients with COVID-19. Regarding the frequency of death, there was no statistical difference in relation to nutritional diagnosis. |
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Martins, Cleide Viviane Buzanellohttp://lattes.cnpq.br/0380880522220338Ferreto , Lirane Elize Defantehttp://lattes.cnpq.br/5828944409163245Martins, Cleide Viviane Buzanellohttp://lattes.cnpq.br/0380880522220338Ferreto, Lirane Elize Defantehttp://lattes.cnpq.br/5828944409163245Wendt, Guilherme Welterhttp://lattes.cnpq.br/3121742068507086Jorge, Alex Sandrohttp://lattes.cnpq.br/2353170679649213http://lattes.cnpq.br/5644551648844400Dal Molin, Bruna Lucas2023-03-15T13:51:39Z2022-12-08DAL MOLIN, Bruna Lucas. Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19. 2022. 48 f. Dissertação (Mestrado em Ciências Aplicadas à Saúde) - Universidade Estadual do Oeste do Paraná, Francisco Beltrão, 2022.https://tede.unioeste.br/handle/tede/6499COVID-19 is an acute respiratory disease caused by SARS-CoV-2 virus infection, which can cause severe hypoxemic respiratory failure, complications, and deaths, especially in the population with chronic health conditions. The mechanisms by which obesity may increase the severity of COVID-19 include physical mechanisms, chronic inflammation, and impaired immune function. In addition, high body mass index is a risk factor for several medical conditions that have been suggested to increase the risk of COVID-19 severity. Objective: to analyze the association between body mass index and clinical outcomes of confirmed cases of COVID-19. Methodology: Cross-sectional study, with data collection from medical records, conducted from March 2020 to December 2021. The records of medical records, biochemical and imaging tests of patients hospitalized with COVID-19 in three hospitals in the city of Francisco Beltrão (PR) were analyzed. The variables analyzed were nutritional diagnosis, age, gender, need for ICU admission, comorbidities, days of hospitalization, complications, laboratory tests and outcome. The inclusion criteria for the study were, hospitalized patients with diagnosis for COVID-19, with presence of nutritional diagnosis reported. Results: In the year 2020, 292 medical records were analyzed and in the year 2021 there were 860 medical records. Of these, only 413 had nutritional diagnosis, thus being included in this study. Were classified as normal weight 78 (18.9%), overweight 153 (37%), and obese 182 (44.1%) participants. The highest prevalence of obesity was found in females (52.5%), patients with diabetes (27.6%), patients with impaired general condition (67.9%), who presented pulmonary complications (54.5%) and arrhythmias (23%). The mean age found in obese patients was younger (55.54) compared to those classified as overweight (59.08) and normal (62.51). It was observed that the higher the BMI the lower were the values found for age (rho = -0.190), leukocytes (rho = -0.109), urea (rho = -0.145) and D-dimer (rho = -0.155). Conclusion: This study provides evidence that overweight and/or obesity then associated with a worse clinical picture during hospitalization of patients with COVID-19. Regarding the frequency of death, there was no statistical difference in relation to nutritional diagnosis.A COVID-19 é uma doença respiratória aguda provocada pela infecção do vírus SARS-CoV-2, que pode causar uma grave insuficiência respiratória hipoxêmica, complicações e mortes, principalmente na população com condições crônicas de saúde. Os mecanismos pelos quais a obesidade pode aumentar a gravidade da COVID-19 incluem mecanismos físicos, inflamação crônica e uma função imunológica prejudicada. Além disso, o índice de massa corporal elevado é um fator de risco para várias condições médicas que têm sido sugeridas para aumentar o risco de gravidade da COVID-19. Objetivo: analisar a associação entre o índice de massa corporal e desfechos clínicos dos casos confirmados de COVID 19. Metodologia: Estudo transversal, com coleta de dados de prontuários, conduzido de março de 2020 a dezembro 2021. Foram analisados os registros de prontuários, exames bioquímicos e de imagem de pacientes internados com COVID 19 em três hospitais da cidade de Francisco Beltrão (PR). As variáveis analisadas foram o diagnóstico nutricional, idade, sexo, necessidade de internação em UTI, comorbidades, dias de hospitalização, complicações, exames laboratoriais e desfecho. Os critérios para inclusão no estudo foram, pacientes hospitalizados com diagnóstico para COVID-19, com presença de diagnóstico nutricional relatado. Resultados: No ano de 2020 foram analisados 292 prontuários e no ano de 2021 foram 860 prontuários. Destes, somente 413 possuíam diagnóstico nutricional, sendo assim incluídos no presente estudo. Foram classificados como peso normal 78 (18,9%), com sobrepeso 153 (37%)e como obeso 182 (44,1%) participantes. A maior prevalência de obesidade foi encontrada no sexo feminino (52,5%), portadores de diabetes (27,6%), pacientes com estado geral comprometido (67,9%), que apresentaram complicações pulmonares (54,5%) e arritmias (23%). A média de idade encontrada em pacientes com obesidade foi mais jovem (55,54) em comparação com os classificados com sobrepeso (59,08) e normal (62,51). Observou-se que quanto maior o IMC menor foram os valores encontrados para idade (rho = -0,190), leucócitos (rho = -0,109), ureia (rho = -0,145) e D-dímero (rho = -0,155). Conclusão: Este estudo fornece evidências de que o sobrepeso e/ou obesidade então associadas a um pior quadro clínico durante a internação dos pacientes com COVID-19. Em relação a frequência de óbito, não houve diferença estatística em relação ao diagnóstico nutricional.Submitted by Almir Squinsani (almir.squinsani@unioeste.br) on 2023-03-15T13:51:39Z No. of bitstreams: 2 Bruna_Molin_2022.pdf: 1401638 bytes, checksum: bc947ff8821e0e28e6baa80c862b504e (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2023-03-15T13:51:39Z (GMT). No. of bitstreams: 2 Bruna_Molin_2022.pdf: 1401638 bytes, checksum: bc947ff8821e0e28e6baa80c862b504e (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2022-12-08application/pdfpor-5356284425524309716500Universidade Estadual do Oeste do ParanáFrancisco BeltrãoPrograma de Pós-Graduação em Ciências Aplicadas à SaúdeUNIOESTEBrasilCentro de Ciências da Saúdehttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessAvaliação nutricionalObesidadeSARS-CoV-2;Coronavírus.Nutritional Assessment;ObesitySARS-CoV-2CoronavirusCIÊNCIAS DA SAÚDEÍndice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19Body mass index and clinical outcomes: a retrospective study in covid-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis6290525253230630664600600292441653440865123reponame:Biblioteca Digital de Teses e Dissertações do UNIOESTEinstname:Universidade Estadual do Oeste do Paraná (UNIOESTE)instacron:UNIOESTEORIGINALBruna_Molin_2022.pdfBruna_Molin_2022.pdfapplication/pdf1401638http://tede.unioeste.br:8080/tede/bitstream/tede/6499/5/Bruna_Molin_2022.pdfbc947ff8821e0e28e6baa80c862b504eMD55CC-LICENSElicense_urllicense_urltext/plain; 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dc.title.por.fl_str_mv |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
dc.title.alternative.eng.fl_str_mv |
Body mass index and clinical outcomes: a retrospective study in covid-19 |
title |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
spellingShingle |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 Dal Molin, Bruna Lucas Avaliação nutricional Obesidade SARS-CoV-2; Coronavírus. Nutritional Assessment; Obesity SARS-CoV-2 Coronavirus CIÊNCIAS DA SAÚDE |
title_short |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
title_full |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
title_fullStr |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
title_full_unstemmed |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
title_sort |
Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19 |
author |
Dal Molin, Bruna Lucas |
author_facet |
Dal Molin, Bruna Lucas |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Martins, Cleide Viviane Buzanello |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/0380880522220338 |
dc.contributor.advisor-co1.fl_str_mv |
Ferreto , Lirane Elize Defante |
dc.contributor.advisor-co1Lattes.fl_str_mv |
http://lattes.cnpq.br/5828944409163245 |
dc.contributor.referee1.fl_str_mv |
Martins, Cleide Viviane Buzanello |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/0380880522220338 |
dc.contributor.referee2.fl_str_mv |
Ferreto, Lirane Elize Defante |
dc.contributor.referee2Lattes.fl_str_mv |
http://lattes.cnpq.br/5828944409163245 |
dc.contributor.referee3.fl_str_mv |
Wendt, Guilherme Welter |
dc.contributor.referee3Lattes.fl_str_mv |
http://lattes.cnpq.br/3121742068507086 |
dc.contributor.referee4.fl_str_mv |
Jorge, Alex Sandro |
dc.contributor.referee4Lattes.fl_str_mv |
http://lattes.cnpq.br/2353170679649213 |
dc.contributor.authorLattes.fl_str_mv |
http://lattes.cnpq.br/5644551648844400 |
dc.contributor.author.fl_str_mv |
Dal Molin, Bruna Lucas |
contributor_str_mv |
Martins, Cleide Viviane Buzanello Ferreto , Lirane Elize Defante Martins, Cleide Viviane Buzanello Ferreto, Lirane Elize Defante Wendt, Guilherme Welter Jorge, Alex Sandro |
dc.subject.por.fl_str_mv |
Avaliação nutricional Obesidade SARS-CoV-2; Coronavírus. |
topic |
Avaliação nutricional Obesidade SARS-CoV-2; Coronavírus. Nutritional Assessment; Obesity SARS-CoV-2 Coronavirus CIÊNCIAS DA SAÚDE |
dc.subject.eng.fl_str_mv |
Nutritional Assessment; Obesity SARS-CoV-2 Coronavirus |
dc.subject.cnpq.fl_str_mv |
CIÊNCIAS DA SAÚDE |
description |
COVID-19 is an acute respiratory disease caused by SARS-CoV-2 virus infection, which can cause severe hypoxemic respiratory failure, complications, and deaths, especially in the population with chronic health conditions. The mechanisms by which obesity may increase the severity of COVID-19 include physical mechanisms, chronic inflammation, and impaired immune function. In addition, high body mass index is a risk factor for several medical conditions that have been suggested to increase the risk of COVID-19 severity. Objective: to analyze the association between body mass index and clinical outcomes of confirmed cases of COVID-19. Methodology: Cross-sectional study, with data collection from medical records, conducted from March 2020 to December 2021. The records of medical records, biochemical and imaging tests of patients hospitalized with COVID-19 in three hospitals in the city of Francisco Beltrão (PR) were analyzed. The variables analyzed were nutritional diagnosis, age, gender, need for ICU admission, comorbidities, days of hospitalization, complications, laboratory tests and outcome. The inclusion criteria for the study were, hospitalized patients with diagnosis for COVID-19, with presence of nutritional diagnosis reported. Results: In the year 2020, 292 medical records were analyzed and in the year 2021 there were 860 medical records. Of these, only 413 had nutritional diagnosis, thus being included in this study. Were classified as normal weight 78 (18.9%), overweight 153 (37%), and obese 182 (44.1%) participants. The highest prevalence of obesity was found in females (52.5%), patients with diabetes (27.6%), patients with impaired general condition (67.9%), who presented pulmonary complications (54.5%) and arrhythmias (23%). The mean age found in obese patients was younger (55.54) compared to those classified as overweight (59.08) and normal (62.51). It was observed that the higher the BMI the lower were the values found for age (rho = -0.190), leukocytes (rho = -0.109), urea (rho = -0.145) and D-dimer (rho = -0.155). Conclusion: This study provides evidence that overweight and/or obesity then associated with a worse clinical picture during hospitalization of patients with COVID-19. Regarding the frequency of death, there was no statistical difference in relation to nutritional diagnosis. |
publishDate |
2022 |
dc.date.issued.fl_str_mv |
2022-12-08 |
dc.date.accessioned.fl_str_mv |
2023-03-15T13:51:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
DAL MOLIN, Bruna Lucas. Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19. 2022. 48 f. Dissertação (Mestrado em Ciências Aplicadas à Saúde) - Universidade Estadual do Oeste do Paraná, Francisco Beltrão, 2022. |
dc.identifier.uri.fl_str_mv |
https://tede.unioeste.br/handle/tede/6499 |
identifier_str_mv |
DAL MOLIN, Bruna Lucas. Índice de massa corporal e desfechos clínicos: um estudo retrospectivo durante a pandemia de covid-19. 2022. 48 f. Dissertação (Mestrado em Ciências Aplicadas à Saúde) - Universidade Estadual do Oeste do Paraná, Francisco Beltrão, 2022. |
url |
https://tede.unioeste.br/handle/tede/6499 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.program.fl_str_mv |
6290525253230630664 |
dc.relation.confidence.fl_str_mv |
600 600 |
dc.relation.department.fl_str_mv |
292441653440865123 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Estadual do Oeste do Paraná Francisco Beltrão |
dc.publisher.program.fl_str_mv |
Programa de Pós-Graduação em Ciências Aplicadas à Saúde |
dc.publisher.initials.fl_str_mv |
UNIOESTE |
dc.publisher.country.fl_str_mv |
Brasil |
dc.publisher.department.fl_str_mv |
Centro de Ciências da Saúde |
publisher.none.fl_str_mv |
Universidade Estadual do Oeste do Paraná Francisco Beltrão |
dc.source.none.fl_str_mv |
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UNIOESTE |
reponame_str |
Biblioteca Digital de Teses e Dissertações do UNIOESTE |
collection |
Biblioteca Digital de Teses e Dissertações do UNIOESTE |
bitstream.url.fl_str_mv |
http://tede.unioeste.br:8080/tede/bitstream/tede/6499/5/Bruna_Molin_2022.pdf http://tede.unioeste.br:8080/tede/bitstream/tede/6499/2/license_url http://tede.unioeste.br:8080/tede/bitstream/tede/6499/3/license_text http://tede.unioeste.br:8080/tede/bitstream/tede/6499/4/license_rdf http://tede.unioeste.br:8080/tede/bitstream/tede/6499/1/license.txt |
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bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 MD5 |
repository.name.fl_str_mv |
Biblioteca Digital de Teses e Dissertações do UNIOESTE - Universidade Estadual do Oeste do Paraná (UNIOESTE) |
repository.mail.fl_str_mv |
biblioteca.repositorio@unioeste.br |
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1798040133210996736 |