Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast.
| Ano de defesa: | 2021 |
|---|---|
| Autor(a) principal: | |
| Orientador(a): | , |
| Banca de defesa: | |
| Tipo de documento: | Dissertação |
| Tipo de acesso: | Acesso aberto |
| Idioma: | por |
| Instituição de defesa: |
Universidade Estadual Paulista (Unesp)
|
| Programa de Pós-Graduação: |
Não Informado pela instituição
|
| Departamento: |
Não Informado pela instituição
|
| País: |
Não Informado pela instituição
|
| Palavras-chave em Português: | |
| Link de acesso: | http://hdl.handle.net/11449/213744 |
Resumo: | O presente estudo teve como objetivo determinar a composição química do extrato etanólico de folhas da espécie Aristolochia warmingii Mast. (Aristolochiaceae). O extrato foi fracionado utilizando técnicas cromatográficas, tais como Cromatografia em Coluna (CC) e Cromatografia Líquida de Alta Eficiência em fase reversa acoplada a Detector de Arranjo de Diodos (CLAE-DAD). As substâncias isoladas foram analisadas por Ressonância Magnética Nuclear e Polarimetria. Ao final foram identificadas dez substâncias, sendo elas: as lignanas tetraidrufurofurânicas epieudesmina, filigenina, episesamina, fargesina, eudesmina e kobusina; a lignana dibenzilbutirolactônica kusunoquinina; duas lignanas tetraidrofurânicas; e o ciclitol metoxilado sequoitol. |
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Antonio, Paulo Vinícius Garcia de [UNESP]Universidade Estadual Paulista (Unesp)Gamboa, Ian CastroDebonsi, Hosana MariaSantos, Lourdes Campaner dos [UNESP]Nascimento, Isabele Rodrigues [UNESP]2021-07-29T17:15:50Z2021-07-29T17:15:50Z2021-07-12http://hdl.handle.net/11449/21374433004030072P833004030072P8O presente estudo teve como objetivo determinar a composição química do extrato etanólico de folhas da espécie Aristolochia warmingii Mast. (Aristolochiaceae). O extrato foi fracionado utilizando técnicas cromatográficas, tais como Cromatografia em Coluna (CC) e Cromatografia Líquida de Alta Eficiência em fase reversa acoplada a Detector de Arranjo de Diodos (CLAE-DAD). As substâncias isoladas foram analisadas por Ressonância Magnética Nuclear e Polarimetria. Ao final foram identificadas dez substâncias, sendo elas: as lignanas tetraidrufurofurânicas epieudesmina, filigenina, episesamina, fargesina, eudesmina e kobusina; a lignana dibenzilbutirolactônica kusunoquinina; duas lignanas tetraidrofurânicas; e o ciclitol metoxilado sequoitol.The present study aimed to determine the chemical composition of the ethanolic extract from the leaves of Aristolochia warmingii Mast. (Aristolochiaceae). The extract was fractionated using chromatographic techniques, such as Column Cromatography (CC) and High-Pressure Liquid Cromatography in reverse phase coupled with a Diode-Array Detector (HPLC-DAD). The compounds were analyzed by Nuclear Magnetic Resonance (NMR) and Polarimetry for the measure of optical activity. Ten compounds were identified: six tetrahydrofurofuran lignans (epieudesmin, phillygenin, episesamin, fargesin, eudesmin, and kobusin); one dibenzylbutyrolactone lignan (kusunokinin); two tetrahydrofuran lignans; and one methoxylated cyclitol (sequoitol).Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)CNPq: 132412/2019-5porUniversidade Estadual Paulista (Unesp)AristolochiaceaeAristolochia warmingiiLignanasLignanas do extrato etanólico de folhas de Aristolochia warmingii Mast.Lignans from the ethanolic extract of the leaves of Aristolochia warmingii Mast.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPQuímica - IQARQuímicaProdutos naturais de plantas e organismos marinhosUniversidade Estadual Paulista (UNESP), Instituto de Química, Araraquara24 meses após a data da defesaBanca públicaPublicationbc74a1ce-4c4c-4dad-8378-83962d76c4fdvirtual::43056-1bc74a1ce-4c4c-4dad-8378-83962d76c4fdvirtual::43056-161afcbc3-9ae1-47a5-b858-c45020d514d5virtual::36892-161afcbc3-9ae1-47a5-b858-c45020d514d5virtual::36892-1THUMBNAILantonio_pvg_me_araiq_par.pdf.jpgWritten by FormatFilter org.dspace.app.mediafilter.PDFBoxThumbnail on 2023-12-10T06:19:59Z (GMT).Generated Thumbnailimage/jpeg2497https://repositorio.unesp.br/bitstreams/af594450-179c-4e5b-84c9-db5306177bd9/download9283de397465d0cfede93fb86b659135MD56falseAnonymousREADantonio_pvg_me_araiq_int.pdf.jpgWritten by FormatFilter org.dspace.app.mediafilter.PDFBoxThumbnail on 2023-12-10T06:20:00Z (GMT).Generated Thumbnailimage/jpeg3419https://repositorio.unesp.br/bitstreams/09ed1161-e18a-43dc-8965-df002decb4bb/download49548b7d6b530ac11270f8a1fd3c1d77MD58falseAnonymousREADORIGINALantonio_pvg_me_araiq_par.pdfantonio_pvg_me_araiq_par.pdfapplication/pdf1905559https://repositorio.unesp.br/bitstreams/2575d221-204f-44ad-bf22-27e8b999bfc5/download057dcfd54b40af42ef3e197c020bc9e2MD53trueAnonymousREADantonio_pvg_me_araiq_int.pdfantonio_pvg_me_araiq_int.pdfapplication/pdf5492045https://repositorio.unesp.br/bitstreams/2c4b96c2-23c0-416f-8e36-b26b29d14559/download261c7382181b0db1de1592211ea70e03MD54falseAnonymousREADLICENSElicense.txtWritten by org.dspace.content.LicenseUtilstext/plain; charset=utf-83046https://repositorio.unesp.br/bitstreams/149e594e-32b1-47cf-8766-ca7a14feba2d/downloadaa8f4aa1609ba870e8450d2361b2decfMD52falseAnonymousREADTEXTantonio_pvg_me_araiq_par.pdf.txtWritten by FormatFilter org.dspace.app.mediafilter.TikaTextExtractionFilter on 2023-12-10T06:19:59Z (GMT).Extracted texttext/plain87092https://repositorio.unesp.br/bitstreams/c8becb8b-4d1a-47ad-a24c-bda35eb34fc7/download87db5ad103fb4adae1dd2a9b324f9125MD55falseAnonymousREADantonio_pvg_me_araiq_int.pdf.txtWritten by FormatFilter org.dspace.app.mediafilter.TikaTextExtractionFilter on 2023-12-10T06:20:00Z (GMT).Extracted texttext/plain102937https://repositorio.unesp.br/bitstreams/ab3f752f-4205-46c7-8dd8-9e23251d5a2d/download16da4304012823d332665bdf8999e4fdMD57falseAnonymousREAD11449/2137442026-03-10T20:07:30.730832Zopen.accessoai:repositorio.unesp.br:11449/213744https://repositorio.unesp.brRepositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestrepositoriounesp@unesp.bropendoar:29462026-03-10T20:07:30Repositório Institucional da UNESP - 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| dc.title.pt.fl_str_mv |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| dc.title.alternative.en.fl_str_mv |
Lignans from the ethanolic extract of the leaves of Aristolochia warmingii Mast. |
| title |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| spellingShingle |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. Antonio, Paulo Vinícius Garcia de [UNESP] Aristolochiaceae Aristolochia warmingii Lignanas |
| title_short |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| title_full |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| title_fullStr |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| title_full_unstemmed |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| title_sort |
Lignanas do extrato etanólico de folhas de Aristolochia warmingii Mast. |
| author |
Antonio, Paulo Vinícius Garcia de [UNESP] |
| author_facet |
Antonio, Paulo Vinícius Garcia de [UNESP] |
| author_role |
author |
| dc.contributor.institution.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
| dc.contributor.committeeMember.none.fl_str_mv |
Gamboa, Ian Castro Debonsi, Hosana Maria |
| dc.contributor.author.fl_str_mv |
Antonio, Paulo Vinícius Garcia de [UNESP] |
| dc.contributor.advisor1.fl_str_mv |
Santos, Lourdes Campaner dos [UNESP] Nascimento, Isabele Rodrigues [UNESP] |
| contributor_str_mv |
Santos, Lourdes Campaner dos [UNESP] Nascimento, Isabele Rodrigues [UNESP] |
| dc.subject.por.fl_str_mv |
Aristolochiaceae Aristolochia warmingii Lignanas |
| topic |
Aristolochiaceae Aristolochia warmingii Lignanas |
| description |
O presente estudo teve como objetivo determinar a composição química do extrato etanólico de folhas da espécie Aristolochia warmingii Mast. (Aristolochiaceae). O extrato foi fracionado utilizando técnicas cromatográficas, tais como Cromatografia em Coluna (CC) e Cromatografia Líquida de Alta Eficiência em fase reversa acoplada a Detector de Arranjo de Diodos (CLAE-DAD). As substâncias isoladas foram analisadas por Ressonância Magnética Nuclear e Polarimetria. Ao final foram identificadas dez substâncias, sendo elas: as lignanas tetraidrufurofurânicas epieudesmina, filigenina, episesamina, fargesina, eudesmina e kobusina; a lignana dibenzilbutirolactônica kusunoquinina; duas lignanas tetraidrofurânicas; e o ciclitol metoxilado sequoitol. |
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2021 |
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2021-07-29T17:15:50Z |
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2021-07-29T17:15:50Z |
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2021-07-12 |
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Universidade Estadual Paulista (Unesp) |
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Universidade Estadual Paulista (Unesp) |
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