Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia

Detalhes bibliográficos
Ano de defesa: 2009
Autor(a) principal: Gakiya, Hugo Higa lattes
Orientador(a): Cassu, Renata Navarro lattes
Banca de defesa: Saidah, Rassen lattes, Nogueira, Rosa Maria Barilli lattes
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade do Oeste Paulista
Programa de Pós-Graduação: Mestrado em Ciência Animal
Departamento: Ciências Agrárias
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://bdtd.unoeste.br:8080/tede/handle/tede/225
Resumo: Electroacupuncture has been shown to be effective in experimental and clinical acute pain settings. The present study aims to evaluate the postoperative cardiopulmonary, sedative and analgesic effects of electroacupuncture, morphine or sham acupuncture in bitches undergoing mastectomy. The 30 dogs were sedated with acepromazine (0.05 mg kg-1, im), followed by induction of anesthesia with propofol (4 mg kg-1) and anesthesia maintenance with isoflurane. The dogs were equally distributed into three treatments that underwent: Gmorf, morphine intramuscular administration; GEA, application of electrical stimuli to acupuncture points; Gsham: similar to the treatment described for GEA, except that the needles were introduced into false points. Heart and respiratory rates, non-invasive systolic arterial pressure, rectal temperature and arterial blood gases, were evaluated during pre and trans-surgery periods. The analgesic and sedation score, as well as the need of rescue analgesia were measured during the first 12 hours after surgery. Statistical analysis was performed using anova for repeated measures to investigate the time in each group and between treatments. Tukey s method was used to contrast group means. Statistics were considered significant at p<0.05. Respecting the cardiorespiratory variables, the systolic arterial pressure was reduced in all groups, during anesthesia. The sedation score was lower in Gsham than in Gmorf, during the first post-surgery hour. The pain score did not differ among the groups, but in the GEA, the animals received less rescue analgesia than the others groups. In conclusion, electroacupuncture reduced the morphine need and promotes satisfactory analgesia in bitches subjected to mastectomy.
id UOES_1545b163aac40f67a743434feb2f654d
oai_identifier_str oai:bdtd.unoeste.br:tede/225
network_acronym_str UOES
network_name_str Biblioteca Digital de Teses e Dissertações da UNOESTE
repository_id_str
spelling Cassu, Renata NavarroCPF:13894409827http://lattes.cnpq.br/1930132389295889Saidah, RassenCPF:73518858920http://lattes.cnpq.br/3202545971151384Nogueira, Rosa Maria BarilliCPF:06991647888http://lattes.cnpq.br/7556647746768615CPF:31058337734http://lattes.cnpq.br/0121968968125116Gakiya, Hugo Higa2016-01-26T18:55:28Z2010-04-272009-08-26GAKIYA, Hugo Higa. Comparative study between the use of electroacupuncture and morphine to postoperative pain management in bitches submitted to mastectomy. 2009. 62 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.http://bdtd.unoeste.br:8080/tede/handle/tede/225Electroacupuncture has been shown to be effective in experimental and clinical acute pain settings. The present study aims to evaluate the postoperative cardiopulmonary, sedative and analgesic effects of electroacupuncture, morphine or sham acupuncture in bitches undergoing mastectomy. The 30 dogs were sedated with acepromazine (0.05 mg kg-1, im), followed by induction of anesthesia with propofol (4 mg kg-1) and anesthesia maintenance with isoflurane. The dogs were equally distributed into three treatments that underwent: Gmorf, morphine intramuscular administration; GEA, application of electrical stimuli to acupuncture points; Gsham: similar to the treatment described for GEA, except that the needles were introduced into false points. Heart and respiratory rates, non-invasive systolic arterial pressure, rectal temperature and arterial blood gases, were evaluated during pre and trans-surgery periods. The analgesic and sedation score, as well as the need of rescue analgesia were measured during the first 12 hours after surgery. Statistical analysis was performed using anova for repeated measures to investigate the time in each group and between treatments. Tukey s method was used to contrast group means. Statistics were considered significant at p<0.05. Respecting the cardiorespiratory variables, the systolic arterial pressure was reduced in all groups, during anesthesia. The sedation score was lower in Gsham than in Gmorf, during the first post-surgery hour. The pain score did not differ among the groups, but in the GEA, the animals received less rescue analgesia than the others groups. In conclusion, electroacupuncture reduced the morphine need and promotes satisfactory analgesia in bitches subjected to mastectomy.A eletroacupuntura (EA) tem se mostrado eficaz no tratamento da dor aguda experimental e clínica. Objetivou-se avaliar os efeitos cardiorrespiratório, sedativo e analgésico pós-operatórios, mediados pela aplicação de morfina, eletroacupuntura ou pontos falsos de acupuntura, em cadelas submetidas à mastectomia. Foram avaliadas 30 cadelas, submetidas à sedação com acepromazina (0,05 mg kg-1,im), seguindo-se a indução e manutenção anestésica com propofol (4 mg kg-1,iv) e isofluorano, respectivamente. Essas pacientes foram distribuídas em três grupos de dez animais cada: Gmorf: administração preemptiva de morfina (0,5 mg kg-1, im), GEA: aplicação de estímulo elétrico em pontos de acupuntura; Gsham: agulhamento em pontos falsos de acupuntura. Foram avaliadas: frequência cardíaca e respiratória, pressão arterial sistólica não invasiva, temperatura retal e variáveis hemogasométricas, durante o período pré e transcirúrgico. O grau de analgesia e sedação, bem como a necessidade de analgesia resgate foram mensurados durante as primeiras 12 horas após a cirurgia. Foi utilizada análise de medidas repetidas e teste de Tukey (p<0,05). Em relação às variáveis cardiorrespiratórias, houve redução da pressão arterial sistólica em todos os grupos, durante a anestesia. O grau de sedação foi inferior no Gsham em relação ao Gmorf, na primeira hora pós-cirúrgica. O escore de dor não variou entre os grupos; porém a analgesia resgate foi menos frequente no GEA, em relação aos demais grupos. Conclui-se que a eletroacupuntura reduziu o requerimento analgésico pós-operatório, de modo a conferir analgesia superior em cadelas submetidas à mastectomia, em relação ao estímulo de pontos falsos e à administração de morfina.Made available in DSpace on 2016-01-26T18:55:28Z (GMT). No. of bitstreams: 1 DISSERTACAO_DR_HUGO_25_02_2010.pdf: 313408 bytes, checksum: ec79a26aefea94b77a4cc0743f1835ff (MD5) Previous issue date: 2009-08-26application/pdfhttp://bdtd.unoeste.br:8080/tede/retrieve/567/DISSERTACAO_DR_HUGO_25_02_2010.pdf.jpgporUniversidade do Oeste PaulistaMestrado em Ciência AnimalUNOESTEBRCiências AgráriasEletroacupunturaOpióidesMastectomiaCãesElectroacupunctureOpioidMastectomyBitches.CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::ANESTESIOLOGIA ANIMALEstudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomiaComparative study between the use of electroacupuncture and morphine to postoperative pain management in bitches submitted to mastectomyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis1886725639743614135500info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UNOESTEinstname:Universidade do Oeste Paulista (UNOESTE)instacron:UNOESTEORIGINALDISSERTACAO_DR_HUGO_25_02_2010.pdfapplication/pdf313408http://bdtd.unoeste.br:8080/tede/bitstream/tede/225/1/DISSERTACAO_DR_HUGO_25_02_2010.pdfec79a26aefea94b77a4cc0743f1835ffMD51THUMBNAILDISSERTACAO_DR_HUGO_25_02_2010.pdf.jpgDISSERTACAO_DR_HUGO_25_02_2010.pdf.jpgimage/jpeg2256http://bdtd.unoeste.br:8080/tede/bitstream/tede/225/2/DISSERTACAO_DR_HUGO_25_02_2010.pdf.jpgd21c1759e4aa33863c806d2497838a23MD52tede/2252016-01-27 01:01:04.57oai:bdtd.unoeste.br:tede/225Biblioteca Digital de Teses e Dissertaçõeshttp://bdtd.unoeste.br:8080/jspui/PUBhttp://bdtd.unoeste.br:8080/oai/requestbdtd@unoeste.bropendoar:2016-01-27T03:01:04Biblioteca Digital de Teses e Dissertações da UNOESTE - Universidade do Oeste Paulista (UNOESTE)false
dc.title.por.fl_str_mv Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
dc.title.alternative.eng.fl_str_mv Comparative study between the use of electroacupuncture and morphine to postoperative pain management in bitches submitted to mastectomy
title Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
spellingShingle Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
Gakiya, Hugo Higa
Eletroacupuntura
Opióides
Mastectomia
Cães
Electroacupuncture
Opioid
Mastectomy
Bitches.
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::ANESTESIOLOGIA ANIMAL
title_short Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
title_full Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
title_fullStr Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
title_full_unstemmed Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
title_sort Estudo comparativo entre o uso de eletroacupuntura e morfina para controle de dor pós-operatória em cadelas submetidas à mastectomia
author Gakiya, Hugo Higa
author_facet Gakiya, Hugo Higa
author_role author
dc.contributor.advisor1.fl_str_mv Cassu, Renata Navarro
dc.contributor.advisor1ID.fl_str_mv CPF:13894409827
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/1930132389295889
dc.contributor.referee1.fl_str_mv Saidah, Rassen
dc.contributor.referee1ID.fl_str_mv CPF:73518858920
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/3202545971151384
dc.contributor.referee2.fl_str_mv Nogueira, Rosa Maria Barilli
dc.contributor.referee2ID.fl_str_mv CPF:06991647888
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/7556647746768615
dc.contributor.authorID.fl_str_mv CPF:31058337734
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/0121968968125116
dc.contributor.author.fl_str_mv Gakiya, Hugo Higa
contributor_str_mv Cassu, Renata Navarro
Saidah, Rassen
Nogueira, Rosa Maria Barilli
dc.subject.por.fl_str_mv Eletroacupuntura
Opióides
Mastectomia
Cães
topic Eletroacupuntura
Opióides
Mastectomia
Cães
Electroacupuncture
Opioid
Mastectomy
Bitches.
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::ANESTESIOLOGIA ANIMAL
dc.subject.eng.fl_str_mv Electroacupuncture
Opioid
Mastectomy
Bitches.
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA::CLINICA E CIRURGIA ANIMAL::ANESTESIOLOGIA ANIMAL
description Electroacupuncture has been shown to be effective in experimental and clinical acute pain settings. The present study aims to evaluate the postoperative cardiopulmonary, sedative and analgesic effects of electroacupuncture, morphine or sham acupuncture in bitches undergoing mastectomy. The 30 dogs were sedated with acepromazine (0.05 mg kg-1, im), followed by induction of anesthesia with propofol (4 mg kg-1) and anesthesia maintenance with isoflurane. The dogs were equally distributed into three treatments that underwent: Gmorf, morphine intramuscular administration; GEA, application of electrical stimuli to acupuncture points; Gsham: similar to the treatment described for GEA, except that the needles were introduced into false points. Heart and respiratory rates, non-invasive systolic arterial pressure, rectal temperature and arterial blood gases, were evaluated during pre and trans-surgery periods. The analgesic and sedation score, as well as the need of rescue analgesia were measured during the first 12 hours after surgery. Statistical analysis was performed using anova for repeated measures to investigate the time in each group and between treatments. Tukey s method was used to contrast group means. Statistics were considered significant at p<0.05. Respecting the cardiorespiratory variables, the systolic arterial pressure was reduced in all groups, during anesthesia. The sedation score was lower in Gsham than in Gmorf, during the first post-surgery hour. The pain score did not differ among the groups, but in the GEA, the animals received less rescue analgesia than the others groups. In conclusion, electroacupuncture reduced the morphine need and promotes satisfactory analgesia in bitches subjected to mastectomy.
publishDate 2009
dc.date.issued.fl_str_mv 2009-08-26
dc.date.available.fl_str_mv 2010-04-27
dc.date.accessioned.fl_str_mv 2016-01-26T18:55:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv GAKIYA, Hugo Higa. Comparative study between the use of electroacupuncture and morphine to postoperative pain management in bitches submitted to mastectomy. 2009. 62 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.
dc.identifier.uri.fl_str_mv http://bdtd.unoeste.br:8080/tede/handle/tede/225
identifier_str_mv GAKIYA, Hugo Higa. Comparative study between the use of electroacupuncture and morphine to postoperative pain management in bitches submitted to mastectomy. 2009. 62 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.
url http://bdtd.unoeste.br:8080/tede/handle/tede/225
dc.language.iso.fl_str_mv por
language por
dc.relation.program.fl_str_mv 1886725639743614135
dc.relation.confidence.fl_str_mv 500
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade do Oeste Paulista
dc.publisher.program.fl_str_mv Mestrado em Ciência Animal
dc.publisher.initials.fl_str_mv UNOESTE
dc.publisher.country.fl_str_mv BR
dc.publisher.department.fl_str_mv Ciências Agrárias
publisher.none.fl_str_mv Universidade do Oeste Paulista
dc.source.none.fl_str_mv reponame:Biblioteca Digital de Teses e Dissertações da UNOESTE
instname:Universidade do Oeste Paulista (UNOESTE)
instacron:UNOESTE
instname_str Universidade do Oeste Paulista (UNOESTE)
instacron_str UNOESTE
institution UNOESTE
reponame_str Biblioteca Digital de Teses e Dissertações da UNOESTE
collection Biblioteca Digital de Teses e Dissertações da UNOESTE
bitstream.url.fl_str_mv http://bdtd.unoeste.br:8080/tede/bitstream/tede/225/1/DISSERTACAO_DR_HUGO_25_02_2010.pdf
http://bdtd.unoeste.br:8080/tede/bitstream/tede/225/2/DISSERTACAO_DR_HUGO_25_02_2010.pdf.jpg
bitstream.checksum.fl_str_mv ec79a26aefea94b77a4cc0743f1835ff
d21c1759e4aa33863c806d2497838a23
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da UNOESTE - Universidade do Oeste Paulista (UNOESTE)
repository.mail.fl_str_mv bdtd@unoeste.br
_version_ 1785359464600174592