Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress

Detalhes bibliográficos
Ano de defesa: 2014
Autor(a) principal: Vasconcelos, Mailton França de
Orientador(a): Almeida, Rosa Maria Martins de
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: eng
Instituição de defesa: Não Informado pela instituição
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Estresse
Psicologia experimental
Vulnerabilidade
Enfrentamento
Ratos Wistar
Inflamação
Link de acesso: http://hdl.handle.net/10183/285335
Resumo: The rat social defeat is ethologically relevant and useful paradigm to understand stress effects. A systematic review of biomarkers induced by social defeat protocol presented in scientific publications in electronic databases in the period of 2002 to 2013 was carried out. Classical and more recently described biomarkers relevant for stress-induced states were identified in the searches. These results were discussed with social defeat protocol relevancy. An experimental study of rat social defeat and immunologic and behavioral stress-induced consequences was executed. The hypothesis of the experimental study are based on evidence that social stress influences immunological responses, also individual variability plays an important influence on effects of stress exposure. In order to evaluate these hypotheses an intermittent social defeat protocol was conducted. Social stress did not affect weight gain and peripheral immunological measures. In the first stress encounter it was possible to characterize individuals in two categories according to their behavioral strategy. These results supported theoretical inferences of social stress equalizing effects on individual reactivity to environmental stimuli.
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spelling Vasconcelos, Mailton França deAlmeida, Rosa Maria Martins de2025-02-15T06:56:42Z2014http://hdl.handle.net/10183/285335000956055The rat social defeat is ethologically relevant and useful paradigm to understand stress effects. A systematic review of biomarkers induced by social defeat protocol presented in scientific publications in electronic databases in the period of 2002 to 2013 was carried out. Classical and more recently described biomarkers relevant for stress-induced states were identified in the searches. These results were discussed with social defeat protocol relevancy. An experimental study of rat social defeat and immunologic and behavioral stress-induced consequences was executed. The hypothesis of the experimental study are based on evidence that social stress influences immunological responses, also individual variability plays an important influence on effects of stress exposure. In order to evaluate these hypotheses an intermittent social defeat protocol was conducted. Social stress did not affect weight gain and peripheral immunological measures. In the first stress encounter it was possible to characterize individuals in two categories according to their behavioral strategy. These results supported theoretical inferences of social stress equalizing effects on individual reactivity to environmental stimuli.application/pdfengEstressePsicologia experimentalVulnerabilidadeEnfrentamentoRatos WistarInflamaçãoStudies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stressinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisUniversidade Federal do Rio Grande do SulInstituto de PsicologiaPrograma de Pós-Graduação em PsicologiaPorto Alegre, BR-RS2014mestradoinfo:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT000956055.pdf.txt000956055.pdf.txtExtracted Texttext/plain183003http://www.lume.ufrgs.br/bitstream/10183/285335/2/000956055.pdf.txt192be96784c38fe475cb3217abb8d43eMD52ORIGINAL000956055.pdfTexto completo (inglês)application/pdf1877502http://www.lume.ufrgs.br/bitstream/10183/285335/1/000956055.pdf46391e290182e0db6b1760dd8e057189MD5110183/2853352025-02-16 06:55:06.777989oai:www.lume.ufrgs.br:10183/285335Biblioteca Digital de Teses e Dissertaçõeshttps://lume.ufrgs.br/handle/10183/2PUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.br||lume@ufrgs.bropendoar:18532025-02-16T09:55:06Biblioteca Digital de Teses e Dissertações da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
title Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
spellingShingle Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
Vasconcelos, Mailton França de
Estresse
Psicologia experimental
Vulnerabilidade
Enfrentamento
Ratos Wistar
Inflamação
title_short Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
title_full Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
title_fullStr Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
title_full_unstemmed Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
title_sort Studies on social defeat : biomarkers of stress-induced states and influences on individual reactivity to social stress
author Vasconcelos, Mailton França de
author_facet Vasconcelos, Mailton França de
author_role author
dc.contributor.author.fl_str_mv Vasconcelos, Mailton França de
dc.contributor.advisor1.fl_str_mv Almeida, Rosa Maria Martins de
contributor_str_mv Almeida, Rosa Maria Martins de
dc.subject.por.fl_str_mv Estresse
Psicologia experimental
Vulnerabilidade
Enfrentamento
Ratos Wistar
Inflamação
topic Estresse
Psicologia experimental
Vulnerabilidade
Enfrentamento
Ratos Wistar
Inflamação
description The rat social defeat is ethologically relevant and useful paradigm to understand stress effects. A systematic review of biomarkers induced by social defeat protocol presented in scientific publications in electronic databases in the period of 2002 to 2013 was carried out. Classical and more recently described biomarkers relevant for stress-induced states were identified in the searches. These results were discussed with social defeat protocol relevancy. An experimental study of rat social defeat and immunologic and behavioral stress-induced consequences was executed. The hypothesis of the experimental study are based on evidence that social stress influences immunological responses, also individual variability plays an important influence on effects of stress exposure. In order to evaluate these hypotheses an intermittent social defeat protocol was conducted. Social stress did not affect weight gain and peripheral immunological measures. In the first stress encounter it was possible to characterize individuals in two categories according to their behavioral strategy. These results supported theoretical inferences of social stress equalizing effects on individual reactivity to environmental stimuli.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2025-02-15T06:56:42Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10183/285335
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