Impact of silicate and phosphate-based dentifrice on enamel subjected to erosion associated with abrasion in situ study

• Ano de defesa: 2025
• Autor(a) principal: Ferdin, Ana Clara Amaro
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: eng
• Instituição de defesa: Biblioteca Digitais de Teses e Dissertações da USP
• Palavras-chave em Português: Cremes dentais; Dental erosion; Erosão dentária; In situ; Toothpastes
• Link de acesso: https://www.teses.usp.br/teses/disponiveis/25/25145/tde-28112025-121721/

Objectives: To evaluate the effectiveness of a toothpaste containing added silicate, phosphate (Refix), and fluoride in preventing enamel wear under conditions of erosion alone and erosion associated with abrasion. Methods: This in situ study employed a crossover, double blind, randomized design conducted over four 5-day phases, with a 7-day washout between phases. The groups under study were: Rege and Regea Refix-based toothpaste; Booste and Boostea Refix-based toothpaste associated with a calcium booster; Elmexe and Elmexea stannous-based toothpaste (positive control); NCe and NCea fluoride-free toothpaste (negative control). Volunteer was the sampling unit (n=16) with 2 enamel blocks per group. The in situ protocol involved 4 daily immersions of the appliance in 1% citric acid (pH 2.5) for 2 min. For erosion plus abrasion, the volunteers brushed their own teeth and the foam produced was spat over the blocks, which were brushed using a power toothbrush for 15 s each. Surface loss was measured by profilometry. Results: Statistical analysis showed a significant difference (p < 0.05) between the wear conditions tested, with greater enamel loss observed in the erosion combined with abrasion groups compared to erosion alone. However, no statistically significant differences were found among toothpastes, nor was there an interaction between toothpastes and condition. Conclusions: Under the conditions of this study, the toothpastes evaluated did not significantly differ in their ability to prevent erosive abrasive enamel wear. Abrasion was identified as the main factor contributing to increased enamel loss.