Analyzing dengue epidemic dynamics using Physics-Informed Neural Networks

• Ano de defesa: 2024
• Autor(a) principal: Souza, Julie
• Orientador(a): Coelho, Flávio Codeço
• Tipo de documento: Tese
• Tipo de acesso: Acesso aberto
• Idioma: eng
• Palavras-chave em Inglês: Physics-Informed Neural Networks (PINNs); Time-varying parameters; Dengue transmission
• Link de acesso: https://hdl.handle.net/10438/36468

This thesis presents a novel approach for modeling dengue epidemics through an adaptation of Physics-Informed Neural Networks (PINNs) designed to model dengue dynamics with time-varying parameters. By incorporating time-varying parameters within a deterministic nonlinear differential equation framework, the approach is particularly well-suited for modeling the complex and evolving nature of dengue transmission, which is marked by serotype variations, changes in population susceptibility, and temporal shifts in transmission dynamics. By applying the model to dengue data from Rio de Janeiro, Goiania, Fortaleza, and Joinville, we examine the role of these parameters in different epidemic scenarios, revealing unique patterns tied to local epidemiological and climatic factors. This city-specific analysis highlights the framework's capacity to capture the interplay of local epidemiology. Furthermore, this study paves the way for future work that integrates climate data into the model, allowing us to simulate disease dynamics under various climate change scenarios.This thesis presents a novel approach for modeling dengue epidemics through an adaptation of Physics-Informed Neural Networks (PINNs) designed to model dengue dynamics with time-varying parameters. By incorporating time-varying parameters within a deterministic nonlinear differential equation framework, the approach is particularly well-suited for modeling the complex and evolving nature of dengue transmission, which is marked by serotype variations, changes in population susceptibility, and temporal shifts in transmission dynamics. By applying the model to dengue data from Rio de Janeiro, Goiania, Fortaleza, and Joinville, we examine the role of these parameters in different epidemic scenarios, revealing unique patterns tied to local epidemiological and climatic factors. This city-specific analysis highlights the framework's capacity to capture the interplay of local epidemiology. Furthermore, this study paves the way for future work that integrates climate data into the model, allowing us to simulate disease dynamics under various climate change scenarios.