Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios

Detalhes bibliográficos
Ano de defesa: 2013
Autor(a) principal: Gomes, ??velim Leal de Freitas Dantas
Orientador(a): Costa, Dirceu lattes
Banca de defesa: Corso, Simone Dal lattes, Angelis, Katia de lattes, Carvalho, Celso Ricardo Fernandes lattes, Stirbulov, Roberto lattes
Tipo de documento: Tese
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Nove de Julho
Programa de Pós-Graduação: Programa de P??s-Gradua????o em Ci??ncias da Reabilita????o
Departamento: Sa??de
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Área do conhecimento CNPq:
Link de acesso: http://bibliotecatede.uninove.br/tede/handle/tede/911
Resumo: Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation.
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spelling Costa, Dirceuhttp://lattes.cnpq.br/7541914413496897Sampaio, Luciana Maria Malos??http://lattes.cnpq.br/2970138065407046Corso, Simone DalCPF:00000000000http://lattes.cnpq.br/9690847988531306Angelis, Katia dehttp://lattes.cnpq.br/4299344810509965Carvalho, Celso Ricardo Fernandeshttp://lattes.cnpq.br/6979390792377484Stirbulov, Robertohttp://lattes.cnpq.br/7405136359510218CPF:25797634813Gomes, ??velim Leal de Freitas Dantas2015-04-22T17:20:47Z2014-12-032013-11-27GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013.http://bibliotecatede.uninove.br/tede/handle/tede/911Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation.Contextualiza????o: A asma ?? uma doen??a respirat??ria cr??nica comum na inf??ncia. A caracter??stica mais marcante ?? a inflama????o persistente das vias a??reas, mesmo nos per??odos fora da crise. O desequil??brio entre os mecanismos pr?? e antiinflamat??rio ?? respons??vel por esta inflama????o cr??nica al??m de uma disfun????o auton??mica que exerce uma influ??ncia importante na patog??nese e no controle da doen??a. O impacto destas altera????es fisiopatol??gicas leva estas crian??as a um ciclo de hipoatividade e sedentarismo influenciando na capacidade funcional e dificultando o controle da doen??a. Objetivos: Avaliar a modula????o auton??mica de crian??as asm??ticas na crise e na fase est??vel, o efeito da press??o positiva cont??nua nas vias a??reas (CPAP) na permeabilidade da via a??rea e na modula????o auton??mica, avaliar a resposta do sistema nervoso auton??mico (SNA) em n??vel m??ximo e subm??ximo de esfor??o f??sico e avaliar a efic??cia de um programa de reabilita????o com v??deo game ativo. M??todos: Foram realizados 3 estudos transversais e um ensaio cl??nico, nos quais foram avaliadas 40 crian??as asm??ticas que se submeteram aprova de fun????o pulmonar (PFP), ??xido N??trico exalado (FeNO), teste ergom??trico (TE), avalia????o de for??a muscular respirat??ria (FMR),variabilidade da freq????ncia card??aca (VFC), Incremental Shuttle Walk Test(ISWT), Teste de Degrau de 3 minutos (TD3), Asthma control questionnaire (ACQ6), medidas antropom??tricas e bioimped??ncia tetrapolar. Resultados: Foi encontrada uma predomin??ncia do sistema nervoso simp??tico na crise de asma ao contr??rio da fase est??vel, em que h?? predomin??ncia do sistema nervoso parassimp??tico. Durante o teste m??ximo, as crian??as asm??ticas n??o fizeram retirada vagal. O peak flow aumentou ap??s a retirada da CPAP, traduzindo poss??vel broncodilata????o, al??m do efeito mec??nico da press??o positiva. O treinamento com v??deo game ativo causou um disp??ndio m??ximo de energia, maior que na esteira, e apresentou melhora da capacidade funcional e inflama????o pulmonar. Conclus??o: H?? diferen??a na modula????o auton??mica das crian??as asm??ticas, na fase est??vel e durante a crise, assim como a resposta do SNA ao esfor??o f??sico m??ximo, quando comparado ao subm??ximo. A CPAP promoveu uma poss??vel broncodilata????o, al??m do efeito mec??nico; ?? poss??vel realizar treinamento aer??bio com v??deo game ativo, com resultado positivo na inflama????o pulmonar.Made available in DSpace on 2015-04-22T17:20:47Z (GMT). No. of bitstreams: 1 Evelim Leal de Freitas Dantas.pdf: 1241922 bytes, checksum: dd1b6c4efcefcbe68b0eddd3ad1bc324 (MD5) Previous issue date: 2013-11-27application/pdfporUniversidade Nove de JulhoPrograma de P??s-Gradua????o em Ci??ncias da Reabilita????oUNINOVEBRSa??deasmamodalidade de fisioterapiaexerc??cio f??sicoinflama????osistema nervoso aut??nomoCPAPasthmaphysiotherapyexerciseinflammationautonomic nervous systemCPAPCIENCIAS DA SAUDEAvalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??riosinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/doctoralThesis8765449414823306929600info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da Uninoveinstname:Universidade Nove de Julho (UNINOVE)instacron:UNINOVEORIGINALEvelim Leal de Freitas Dantas.pdfapplication/pdf1241922http://localhost:8080/tede/bitstream/tede/911/1/Evelim+Leal+de+Freitas+Dantas.pdfdd1b6c4efcefcbe68b0eddd3ad1bc324MD51tede/9112018-06-15 12:24:36.063oai:localhost:tede/911Biblioteca Digital de Teses e Dissertaçõeshttp://bibliotecatede.uninove.br/PRIhttp://bibliotecatede.uninove.br/oai/requestbibliotecatede@uninove.br||bibliotecatede@uninove.bropendoar:2018-06-15T15:24:36Biblioteca Digital de Teses e Dissertações da Uninove - Universidade Nove de Julho (UNINOVE)false
dc.title.por.fl_str_mv Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
title Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
spellingShingle Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
Gomes, ??velim Leal de Freitas Dantas
asma
modalidade de fisioterapia
exerc??cio f??sico
inflama????o
sistema nervoso aut??nomo
CPAP
asthma
physiotherapy
exercise
inflammation
autonomic nervous system
CPAP
CIENCIAS DA SAUDE
title_short Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
title_full Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
title_fullStr Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
title_full_unstemmed Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
title_sort Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios
author Gomes, ??velim Leal de Freitas Dantas
author_facet Gomes, ??velim Leal de Freitas Dantas
author_role author
dc.contributor.advisor1.fl_str_mv Costa, Dirceu
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/7541914413496897
dc.contributor.advisor-co1.fl_str_mv Sampaio, Luciana Maria Malos??
dc.contributor.advisor-co1Lattes.fl_str_mv http://lattes.cnpq.br/2970138065407046
dc.contributor.referee1.fl_str_mv Corso, Simone Dal
dc.contributor.referee1ID.fl_str_mv CPF:00000000000
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/9690847988531306
dc.contributor.referee2.fl_str_mv Angelis, Katia de
dc.contributor.referee2Lattes.fl_str_mv http://lattes.cnpq.br/4299344810509965
dc.contributor.referee3.fl_str_mv Carvalho, Celso Ricardo Fernandes
dc.contributor.referee3Lattes.fl_str_mv http://lattes.cnpq.br/6979390792377484
dc.contributor.referee4.fl_str_mv Stirbulov, Roberto
dc.contributor.referee4Lattes.fl_str_mv http://lattes.cnpq.br/7405136359510218
dc.contributor.authorID.fl_str_mv CPF:25797634813
dc.contributor.author.fl_str_mv Gomes, ??velim Leal de Freitas Dantas
contributor_str_mv Costa, Dirceu
Sampaio, Luciana Maria Malos??
Corso, Simone Dal
Angelis, Katia de
Carvalho, Celso Ricardo Fernandes
Stirbulov, Roberto
dc.subject.por.fl_str_mv asma
modalidade de fisioterapia
exerc??cio f??sico
inflama????o
sistema nervoso aut??nomo
CPAP
topic asma
modalidade de fisioterapia
exerc??cio f??sico
inflama????o
sistema nervoso aut??nomo
CPAP
asthma
physiotherapy
exercise
inflammation
autonomic nervous system
CPAP
CIENCIAS DA SAUDE
dc.subject.eng.fl_str_mv asthma
physiotherapy
exercise
inflammation
autonomic nervous system
CPAP
dc.subject.cnpq.fl_str_mv CIENCIAS DA SAUDE
description Background: Asthma is the most common chronic respiratory disease in childhood. The most striking feature is the persistent inflammation of the airways, even in periods of crisis. The imbalance between the pro and anti-inflammatory mechanisms are responsible for this chronic inflammation as an autonomic dysfunction that exerts an important influence on pathogenesis and control of the disease. The impact of these changes takes these children a patho-physiological cycle of underactive and sedentariness influencing on functional capacity and making the control of the disease worse. Objectives: to evaluate the autonomic modulation of asthmatic children in crisis and in stable phase, the effect of continuous positive airway pressure (CPAP) on airway permeability and autonomic modulation, evaluate the response of the autonomic nervous system (ANS) is at maximum and submaximal exercise and assess the effectiveness of a rehabilitation programme with active video game. Methods: 3 cross-sectional studies and a clinical trial were carried out, in which were evaluated 40 asthmatic children who underwent pulmonary function test (PFT), exhaled Nitric Oxide (FeNO), exercise testing (ET), respiratory muscle strength assessment (RMS), heart rate variability (HRV), Incremental Shuttle Walk Test (ISWT), 3-minute step test (ST3), Asthma control questionnaire (ACQ6), anthropometric measurements and tetrapolar bioelectrical impedance. Results: it was found a prevalence of sympathetic nervous system on asthma crisis unlike the stable phase, in which there is predominance of the parasympathetic nervous system. During the maximum test of asthmatic children hasn t had vagal withdrawal. The peak flow has increased after the withdrawal of CPAP, translating as possible, in addition to the mechanical effect bronchodilation positive pressure. Training with active video game caused a maximum expenditure of energy, bigger than on the treadmill, and featured improved functional capacity and lung inflammation. Conclusion: there is a difference in the autonomic modulation of asthmatic children in stable phase and during the crisis, as well as ANS's response to maximum physical effort when compared to the submaximal exercise. The CPAP promoted a possible bronchodilation, besides the mechanical effect; Is possible perform aerobic training with active video game, with positive outcome in lung inflammation.
publishDate 2013
dc.date.issued.fl_str_mv 2013-11-27
dc.date.available.fl_str_mv 2014-12-03
dc.date.accessioned.fl_str_mv 2015-04-22T17:20:47Z
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dc.identifier.citation.fl_str_mv GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013.
dc.identifier.uri.fl_str_mv http://bibliotecatede.uninove.br/tede/handle/tede/911
identifier_str_mv GOMES, ??velim Leal de Freitas Dantas. Avalia????o e reabilita????o de crian??as asm??ticas nos desfechos funcionais, auton??micos e inflamat??rios. 2013. 75 f. Tese (Doutorado em Sa??de) - Universidade Nove de Julho, S??o Paulo, 2013.
url http://bibliotecatede.uninove.br/tede/handle/tede/911
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dc.relation.cnpq.fl_str_mv 8765449414823306929
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dc.publisher.country.fl_str_mv BR
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publisher.none.fl_str_mv Universidade Nove de Julho
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