Polimorfismos do gene DGAT1 (região 5’UTR) em bovinos nelores (PO) e mestiços (SRD), e sua relação com a circunferência escrotal e abertura bi isquiática

• Ano de defesa: 2017
• Autor(a) principal: Freire, Kelia Margarida Barros
• Orientador(a): Cruz, Alex Silva da
• Banca de defesa: Moura, Maria Ivete de , Silva, Cláudio Carlos da
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica de Goiás
• Programa de Pós-Graduação: Programa de Pós-Graduação STRICTO SENSU em Genética
• Departamento: Escola de Ciências Agrárias e Biológicas::Curso de Biologia Bacharelado
• País: Brasil
• Palavras-chave em Português: Decodificação. Fenótipo. Gado. Genoma. Genótipo. Seleção.
• Palavras-chave em Inglês: Catlle. Decoding. Genome. Genotype. Phenotype. Selection.
• Área do conhecimento CNPq: CIENCIAS BIOLOGICAS::GENETICA
• Link de acesso: https://tede2.pucgoias.edu.br/handle/tede/3714

After the opening of diverse branches of Genetics Science, and the decoding of human and animal (bovine) genome, our production animals are being evaluated by molecular markers, which read the genome and translate it in four letters: AT-CG. The variations are analyzed as monomorphic and polymorphic regions. The aim of this research was to evaluate the “polymorphisms of the gene DGAT1 and its relation to the external sciatic bi opening and the scrotal circumference”. 109 animals have been analyzed, n= 73 Nelores bovines and n= 36 with no determined breed (NDB), with the age adjusted to 550 days, owned by breeders from the state of Goiás. In the morphometric data analysis through the test T of Student, comparing the groups Nelores PO and Bovine NDB, The analysis of morphometric data through the test T of Student comparing the groups Nelore PO and Bovine NDB does not indicate that the identified differences are substantially important to the variables ABi and CE (p ≤ 0,0001). In the genomic analysis, the test Chi-square was not relevant (p ≥ 0,05), revealing, this, that the groups of Nelore PO and of animals of NDB do not differ when it comes to the obtained genotypic and allelic frequencies. In this situation, we have observed so far variations in the allelic and genotypic frequencies for the sampled animals and the three SNP used in the study: rs471462296, rs456245081 and rs438495570. The genotype of the sampled bovines did not affect the evaluated characteristics, revealing there are, this, other genetic and non-genetic effects which affect the characteristics studied in Nelore, which deserve to be investigated.