Análise cienciométrica do polimorfismo genético na infertilidade

• Ano de defesa: 2019
• Autor(a) principal: Duarte, Fernanda Melo
• Orientador(a): Moura, Katia Karina Verolli de Oliveira
• Banca de defesa: Reis, Paulo Roberto de Melo , Silva, Kleber Santiago Freitas e
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Pontifícia Universidade Católica de Goiás
• Programa de Pós-Graduação: Programa de Pós-Graduação STRICTO SENSU em Genética
• Departamento: Escola de Ciências Agrárias e Biológicas::Curso de Biologia Bacharelado
• País: Brasil
• Palavras-chave em Português: Cienciometria, Genes polimórficos, Infertilidade, Etiologia.
• Palavras-chave em Inglês: Scientometry, polymorphic genes, infertility, etiology.
• Área do conhecimento CNPq: CIENCIAS BIOLOGICAS::GENETICA
• Link de acesso: https://tede2.pucgoias.edu.br/handle/tede/4226

Infertility is an anomaly of the reproductive system defined by the failure to achieve a clinical pregnancy through regular and unprotected sexual intercourse. Infertility is a multifactorial disease and affects both males and females. Genetic causes are intrinsically related to the aetiologies of infertility, thus, the understanding of the genetic polymorphisms associated with male and female infertility deserves the geneticists attention. The objective of this study was to characterize the scientific production related to genetic polymorphisms and infertility in the period from 1994 to 2017, in order to verify trends and perspectives of the scientific development by means of scientometrics analysis. For this, a bibliographic survey was carried out on the Scopus® site. The keywords "genetic* polymorphism*" AND infertility OR "molecular* MARKER*” AND INFERTILITY* were used. Several evaluation approaches were carried out: number of articles/year, publication type, journals, authors and countries that have published more frequently regarding infertility and main causes and polymorphic genes related to infertility. As a result, there was an increase in the number of publications related to genetic polymorphism and infertility over the years. The prevalence of publication is from China followed by Brazil. We identified 73 polymorphic genes for female infertility and 70 polymorphic genes for male infertility. The causes of infertility related to polymorphic genes comprise a very broad study and it has been shown that increasing the number of samples surveyed may contribute to pointing relationships between polymorphisms and infertility.