Fatores relacionados aos níveis de retinol sérico em crianças de seis a 24 meses de creches municipais de Goiânia-Goiás

• Ano de defesa: 2013
• Autor(a) principal: Lobo, Lina Monteiro de Castro
• Orientador(a): Hadler, Maria Claret Costa Monteiro
• Banca de defesa: Hadler, Maria Claret Costa Monteiro, Pereira Netto, MIchele, Menezes, Ida Helena Carvalho Francescantonio, Peixoto, Maria do Rosário Gondim, Martins, Karine Anusca
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Instituição de defesa: Universidade Federal de Goiás
• Programa de Pós-Graduação: Programa de Pós-graduação em Nutrição e Saúde (FANUT)
• Departamento: Faculdade de Nutrição - FANUT (RG)
• País: Brasil
• Palavras-chave em Português: Deficiência de vitamina A; Pré-escolar; Vitamina A; Micronutrientes; Saúde da criança
• Palavras-chave em Inglês: Vitamin A deficiency; Preschooler; Vitamin A; Micronutrients; Children’s health
• Área do conhecimento CNPq: CIENCIAS DA SAUDE::NUTRICAO
• Link de acesso: http://repositorio.bc.ufg.br/tede/handle/tede/8624

Introduction: Vitamin A deficiency can increase susceptibility to infection and reduce growth rate, besides it is an important cause of blindness in childhood. Infants and preschools are the most vulnerable groups to this deficiency. Objective: To evaluate the factors related to serum retinol in infants aged from six to 24 months who were attended at municipal daycare centers (CMEIs) in the city of Goiânia - Goiás State, Brasil. Methods: A cross-sectional study, undertaken between 2005 and 2006 in CMEIs located in Goiânia. A socioeconomic and demographic survey was performed as well as blood samples were drawn from 193 infants to analysis of complete blood count (CBC), serum retinol, ferritin and C-reactive protein (CRP). Retinol was determined by High Performance Liquid Chromatography (HPLC) being considered deficient retinol levels under 0,7 μmol/L. Data were analyzed by the softwares Stata/SE 12.0 and Statistical Package for the Social Sciences 18.0 (SPSS). T student test, Pearson’s or Spearman’s correlation and multiple linear regression were performed. Results: The mean serum of retinol level was of 1,00 ± 0,38 μmol/L and the prevalence of vitamin A deficiency was of 21,8%. The average levels of retinol did not differ significantly between gender, age, type of water consumed, prenatal assistance, breastfeeding (predominant or current), presence or absence of anemia and ferritin levels. There was no correlation between the mother’s schooling, birth weight and number of infants younger than five years of age with serum retinol. There was association between vitamin A deficiency and inflammation (p=0,04). For each CRP unit that increased there was a reduction of 0,133 e 0,115 mg/dL in serum retinol levels, according to two models of multiple linear regression, keeping other variables constant. Conclusion: Vitamin A deficiency in infants who were attended at a municipal daycare centers in Goiânia is high and the factor related to this deficiency was the inflammatory state of the child which is represented by the CRP serum levels, adjusted by sanitary sewage, habitation location and ferritin level.