Desenvolvimento de sistemas nanoestruturados contendo TiO2 e manteiga de ucuuba para obtenção de formulações fotoprotetoras multifuncionais

• Ano de defesa: 2022
• Autor(a) principal: Andrade, Ane Karoline Silva
• Orientador(a): Kaminski, Renata Cristina Kiatkoski
• Tipo de documento: Dissertação
• Tipo de acesso: Acesso aberto
• Idioma: por
• Programa de Pós-Graduação: Pós-Graduação em Química
• Palavras-chave em Português: Protetores contra radiação; Dióxido de titânio; Cristais líquidos; Cosméticos; Filtros solares inorgânicos; Tween 80; Virola surinamensis; Cosmético
• Palavras-chave em Inglês: Inorganic sunscreens; Titanium dioxide; Tween 80; Liquid crystals; Virola surinamensis; Cosmetic
• Área do conhecimento CNPq: CIENCIAS EXATAS E DA TERRA::QUIMICA
• Link de acesso: http://ri.ufs.br/jspui/handle/riufs/15824

Excessive exposure to the ultraviolet rays is the leading cause of skin cancer in the world. One of the most effective ways to prevent the harmful effects of exposure to sunlight is with the proper use of sunscreens. In this sense, sunscreens based on inorganic actives based on TiO2 nanoparticles, offer advantages such as the low potential to cause allergies and, even when associated with the incorporation of other substances of interest, become multifunctional cosmetic. Thus, this work aims to develop multifunctional photoprotective formulations from nanostructured systems composed of TiO2 and ucuuba butter, as it has antifungal, antibacterial, and anti-inflammatory properties, in addition to high moisturizing potential. The formulations were prepared using ternary mixtures of water, ucuuba butter (oily phase), and Tween 80 (surfactant), in different proportions, in order to evaluate the effects of butter on the liquid crystal structure and on the occlusive capacity of the emulsified systems. Small Angle X-Ray Scattering (SAXS) analysis showed the formation of liquid-crystalline structures in the formulations, with cubic and hexagonal mesophases. The flow rheological analysis showed that the formulation had a pseudoplastic character, with a low degree of rheopexy being observed for the sample with 40% of surfactant. The oscillatory test showed that the increase in the amount of oil phase tends to form gel-like structures. The results of the stability tests showed that there is a change in the behavior of the system with the addition of TiO2 nanoparticles, due to the interaction of the existing charges. The occlusion study suggested that increasing the amount of oil phase and the addition of TiO2 nanoparticles provides a greater occlusive effect to the formulations. Thus, the present work allowed us to obtain promising nanostructured systems for the production of a multifunctional sunscreen.