Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico

Detalhes bibliográficos
Ano de defesa: 2009
Autor(a) principal: Viel, Rosilene Martins
Orientador(a): Nogueira, Rosa Maria Barilli lattes
Banca de defesa: Kitamura, Eunice Akemi lattes, Laposy, Cecília Braga
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade do Oeste Paulista
Programa de Pós-Graduação: Mestrado em Ciência Animal
Departamento: Ciências Agrárias
País: BR
Palavras-chave em Português:
Palavras-chave em Inglês:
Dog
Área do conhecimento CNPq:
Link de acesso: http://bdtd.unoeste.br:8080/tede/handle/tede/229
Resumo: Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug.
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spelling Nogueira, Rosa Maria BarilliCPF:06991647888http://lattes.cnpq.br/7556647746768615Kitamura, Eunice AkemiCPF:14746092877http://lattes.cnpq.br/4559644332065994Laposy, Cecília BragaCPF:11651891869CPF:05881654846Viel, Rosilene Martins2016-01-26T18:55:29Z2009-11-122009-06-26VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.http://bdtd.unoeste.br:8080/tede/handle/tede/229Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug.Salbutamol e fenoterol são agonistas β2 adrenérgicos de curta duração, com papel importante no tratamento das doenças respiratórias devido ao seu excelente efeito broncodilatador. O presente estudo teve como objetivo avaliar por meio de exame físico, laboratorial e eletrocardiográfico os efeitos destes fármacos administrados por via inalatória em cães. Doze cães foram distribuídos em dois grupos com seis em cada sendo: grupo FE (fenoterol) recebeu fenoterol via inalatória, na dose de 2 gotas/5Kg de peso vivo, diluídas em solução de cloreto de sódio 0,9% e administrados por meio do aparelho de inalação; grupo SA (salbutamol) tratado com salbutamol, por meio de dosador de aerossol, na dose de 100mg. Foram avaliados quatro diferentes momentos, sendo considerado MC (momento controle) antes da administração dos fármacos, M30, M2 e M6, onde as avaliações foram realizadas com 30 minutos, 2 horas e 6 horas após administração dos fármacos respectivamente. Foram aferidas temperatura retal(TR), freqüência cardíaca (FC), freqüência respiratória (FR), pressão arterial sistólica (PAS), avaliados a hemogasometria e eletrocardiograma. O fenoterol e salbutamol causaram discreta estimulação cardíaca, sendo estatisticamente significativo para os animais do grupo SA 2 horas após a sua administração comparado ao momento controle. Tremores foram observados com maior predominância nos animais do grupo SA. Diminuição da pressão arterial sistólica e aumento da freqüência respiratória foram observados nos dois grupos, e não houve alteração significativa da temperatura retal, dos valores da hemogasometria e eletrocardiograma em ambos os grupos. Conclui-se que o fenoterol provoca menor efeitos colaterais de estimulação cardíaca e tremores comparados ao salbutamol sendo desta forma um fármaco mais seguro.Made available in DSpace on 2016-01-26T18:55:29Z (GMT). No. of bitstreams: 1 Dissertacao.pdf: 262952 bytes, checksum: fed2a60f7a0605b64f30fb2d2656c986 (MD5) Previous issue date: 2009-06-26application/pdfhttp://bdtd.unoeste.br:8080/tede/retrieve/590/Dissertacao.pdf.jpgporUniversidade do Oeste PaulistaMestrado em Ciência AnimalUNOESTEBRCiências AgráriasFenoterolSalbutamolInalaçãoCãoFenoterolSalbutamolInhalationDogCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAFenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográficoFenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis1886725639743614135500info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UNOESTEinstname:Universidade do Oeste Paulista (UNOESTE)instacron:UNOESTEORIGINALDissertacao.pdfapplication/pdf262952http://bdtd.unoeste.br:8080/tede/bitstream/tede/229/1/Dissertacao.pdffed2a60f7a0605b64f30fb2d2656c986MD51THUMBNAILDissertacao.pdf.jpgDissertacao.pdf.jpgimage/jpeg3022http://bdtd.unoeste.br:8080/tede/bitstream/tede/229/2/Dissertacao.pdf.jpga41232039e82935e576e4585e1e38537MD52tede/2292016-01-27 01:01:24.516oai:bdtd.unoeste.br:tede/229Biblioteca Digital de Teses e Dissertaçõeshttp://bdtd.unoeste.br:8080/jspui/PUBhttp://bdtd.unoeste.br:8080/oai/requestbdtd@unoeste.bropendoar:2016-01-27T03:01:24Biblioteca Digital de Teses e Dissertações da UNOESTE - Universidade do Oeste Paulista (UNOESTE)false
dc.title.por.fl_str_mv Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
dc.title.alternative.eng.fl_str_mv Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects
title Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
spellingShingle Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
Viel, Rosilene Martins
Fenoterol
Salbutamol
Inalação
Cão
Fenoterol
Salbutamol
Inhalation
Dog
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
title_short Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
title_full Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
title_fullStr Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
title_full_unstemmed Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
title_sort Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
author Viel, Rosilene Martins
author_facet Viel, Rosilene Martins
author_role author
dc.contributor.advisor1.fl_str_mv Nogueira, Rosa Maria Barilli
dc.contributor.advisor1ID.fl_str_mv CPF:06991647888
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/7556647746768615
dc.contributor.referee1.fl_str_mv Kitamura, Eunice Akemi
dc.contributor.referee1ID.fl_str_mv CPF:14746092877
dc.contributor.referee1Lattes.fl_str_mv http://lattes.cnpq.br/4559644332065994
dc.contributor.referee2.fl_str_mv Laposy, Cecília Braga
dc.contributor.referee2ID.fl_str_mv CPF:11651891869
dc.contributor.authorID.fl_str_mv CPF:05881654846
dc.contributor.author.fl_str_mv Viel, Rosilene Martins
contributor_str_mv Nogueira, Rosa Maria Barilli
Kitamura, Eunice Akemi
Laposy, Cecília Braga
dc.subject.por.fl_str_mv Fenoterol
Salbutamol
Inalação
Cão
topic Fenoterol
Salbutamol
Inalação
Cão
Fenoterol
Salbutamol
Inhalation
Dog
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
dc.subject.eng.fl_str_mv Fenoterol
Salbutamol
Inhalation
Dog
dc.subject.cnpq.fl_str_mv CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA
description Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug.
publishDate 2009
dc.date.available.fl_str_mv 2009-11-12
dc.date.issued.fl_str_mv 2009-06-26
dc.date.accessioned.fl_str_mv 2016-01-26T18:55:29Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
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dc.identifier.citation.fl_str_mv VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.
dc.identifier.uri.fl_str_mv http://bdtd.unoeste.br:8080/tede/handle/tede/229
identifier_str_mv VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.
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