Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico
Ano de defesa: | 2009 |
---|---|
Autor(a) principal: | |
Orientador(a): | |
Banca de defesa: | , |
Tipo de documento: | Dissertação |
Tipo de acesso: | Acesso aberto |
Idioma: | por |
Instituição de defesa: |
Universidade do Oeste Paulista
|
Programa de Pós-Graduação: |
Mestrado em Ciência Animal
|
Departamento: |
Ciências Agrárias
|
País: |
BR
|
Palavras-chave em Português: | |
Palavras-chave em Inglês: | |
Área do conhecimento CNPq: | |
Link de acesso: | http://bdtd.unoeste.br:8080/tede/handle/tede/229 |
Resumo: | Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug. |
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Nogueira, Rosa Maria BarilliCPF:06991647888http://lattes.cnpq.br/7556647746768615Kitamura, Eunice AkemiCPF:14746092877http://lattes.cnpq.br/4559644332065994Laposy, Cecília BragaCPF:11651891869CPF:05881654846Viel, Rosilene Martins2016-01-26T18:55:29Z2009-11-122009-06-26VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009.http://bdtd.unoeste.br:8080/tede/handle/tede/229Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug.Salbutamol e fenoterol são agonistas β2 adrenérgicos de curta duração, com papel importante no tratamento das doenças respiratórias devido ao seu excelente efeito broncodilatador. O presente estudo teve como objetivo avaliar por meio de exame físico, laboratorial e eletrocardiográfico os efeitos destes fármacos administrados por via inalatória em cães. Doze cães foram distribuídos em dois grupos com seis em cada sendo: grupo FE (fenoterol) recebeu fenoterol via inalatória, na dose de 2 gotas/5Kg de peso vivo, diluídas em solução de cloreto de sódio 0,9% e administrados por meio do aparelho de inalação; grupo SA (salbutamol) tratado com salbutamol, por meio de dosador de aerossol, na dose de 100mg. Foram avaliados quatro diferentes momentos, sendo considerado MC (momento controle) antes da administração dos fármacos, M30, M2 e M6, onde as avaliações foram realizadas com 30 minutos, 2 horas e 6 horas após administração dos fármacos respectivamente. Foram aferidas temperatura retal(TR), freqüência cardíaca (FC), freqüência respiratória (FR), pressão arterial sistólica (PAS), avaliados a hemogasometria e eletrocardiograma. O fenoterol e salbutamol causaram discreta estimulação cardíaca, sendo estatisticamente significativo para os animais do grupo SA 2 horas após a sua administração comparado ao momento controle. Tremores foram observados com maior predominância nos animais do grupo SA. Diminuição da pressão arterial sistólica e aumento da freqüência respiratória foram observados nos dois grupos, e não houve alteração significativa da temperatura retal, dos valores da hemogasometria e eletrocardiograma em ambos os grupos. Conclui-se que o fenoterol provoca menor efeitos colaterais de estimulação cardíaca e tremores comparados ao salbutamol sendo desta forma um fármaco mais seguro.Made available in DSpace on 2016-01-26T18:55:29Z (GMT). No. of bitstreams: 1 Dissertacao.pdf: 262952 bytes, checksum: fed2a60f7a0605b64f30fb2d2656c986 (MD5) Previous issue date: 2009-06-26application/pdfhttp://bdtd.unoeste.br:8080/tede/retrieve/590/Dissertacao.pdf.jpgporUniversidade do Oeste PaulistaMestrado em Ciência AnimalUNOESTEBRCiências AgráriasFenoterolSalbutamolInalaçãoCãoFenoterolSalbutamolInhalationDogCNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIAFenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográficoFenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspectsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesis1886725639743614135500info:eu-repo/semantics/openAccessreponame:Biblioteca Digital de Teses e Dissertações da UNOESTEinstname:Universidade do Oeste Paulista (UNOESTE)instacron:UNOESTEORIGINALDissertacao.pdfapplication/pdf262952http://bdtd.unoeste.br:8080/tede/bitstream/tede/229/1/Dissertacao.pdffed2a60f7a0605b64f30fb2d2656c986MD51THUMBNAILDissertacao.pdf.jpgDissertacao.pdf.jpgimage/jpeg3022http://bdtd.unoeste.br:8080/tede/bitstream/tede/229/2/Dissertacao.pdf.jpga41232039e82935e576e4585e1e38537MD52tede/2292016-01-27 01:01:24.516oai:bdtd.unoeste.br:tede/229Biblioteca Digital de Teses e Dissertaçõeshttp://bdtd.unoeste.br:8080/jspui/PUBhttp://bdtd.unoeste.br:8080/oai/requestbdtd@unoeste.bropendoar:2016-01-27T03:01:24Biblioteca Digital de Teses e Dissertações da UNOESTE - Universidade do Oeste Paulista (UNOESTE)false |
dc.title.por.fl_str_mv |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
dc.title.alternative.eng.fl_str_mv |
Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects |
title |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
spellingShingle |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico Viel, Rosilene Martins Fenoterol Salbutamol Inalação Cão Fenoterol Salbutamol Inhalation Dog CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
title_short |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
title_full |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
title_fullStr |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
title_full_unstemmed |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
title_sort |
Fenoterol e Salbutamol via inalatória em cães: aspectos clínico, laboratorial e eletrocardiográfico |
author |
Viel, Rosilene Martins |
author_facet |
Viel, Rosilene Martins |
author_role |
author |
dc.contributor.advisor1.fl_str_mv |
Nogueira, Rosa Maria Barilli |
dc.contributor.advisor1ID.fl_str_mv |
CPF:06991647888 |
dc.contributor.advisor1Lattes.fl_str_mv |
http://lattes.cnpq.br/7556647746768615 |
dc.contributor.referee1.fl_str_mv |
Kitamura, Eunice Akemi |
dc.contributor.referee1ID.fl_str_mv |
CPF:14746092877 |
dc.contributor.referee1Lattes.fl_str_mv |
http://lattes.cnpq.br/4559644332065994 |
dc.contributor.referee2.fl_str_mv |
Laposy, Cecília Braga |
dc.contributor.referee2ID.fl_str_mv |
CPF:11651891869 |
dc.contributor.authorID.fl_str_mv |
CPF:05881654846 |
dc.contributor.author.fl_str_mv |
Viel, Rosilene Martins |
contributor_str_mv |
Nogueira, Rosa Maria Barilli Kitamura, Eunice Akemi Laposy, Cecília Braga |
dc.subject.por.fl_str_mv |
Fenoterol Salbutamol Inalação Cão |
topic |
Fenoterol Salbutamol Inalação Cão Fenoterol Salbutamol Inhalation Dog CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
dc.subject.eng.fl_str_mv |
Fenoterol Salbutamol Inhalation Dog |
dc.subject.cnpq.fl_str_mv |
CNPQ::CIENCIAS AGRARIAS::MEDICINA VETERINARIA |
description |
Salbutamol and fenoterol are agonists β2 adrenergic of short duration, with important paper in the treatment of the breathing diseases due to excellent effect bronchodilator. The study had as objective evaluates through physical exam, laboratorial and electrocardiography the effects of the fenoterol and salbutamol for road inalatory in dogs. Twelve dogs were distributed in 2 groups being: group FE (fenoterol) it received fenoterol through inalatory, in the dose of 2droups/5Kg of alive weight diluted in solution of chloride of sodium 0,9% and administered by road inalatory through the inhalation apparel; group SA (salbutamol) treaty with salbutamol, through aerosol dosador, in the dose of 100 micrograms. They were appraised four different moments, being considered MC (moment controls) before the administration of the drug, M30, M2 and M6, where the evaluations were accomplished respectively with 30 minutes, 2 hours and 6 hours after administration of the drugs. They were checked temperature (T), heart frequency (FC), breathing frequency (f), systolic blood pressure (PAS), appraised the gasometry and electrocardiogram. The fenoterol and salbutamol caused discreet heart stimulation, being significant for the animals of the group SA two hours after the administration of the drug compared a moment controls. Tremors were observed with larger predominance in the animals of the group SA. Decrease of the systolic blood pressure and increase of the breathing frequency were observed in the two groups, and there were not significant alteration of the temperature, gasometry and electrocardiogram for both groups. Was ended that the fenoterol provokes smaller side effects of heart stimulation and tremors compared to the salbutamol being this way a safer drug. |
publishDate |
2009 |
dc.date.available.fl_str_mv |
2009-11-12 |
dc.date.issued.fl_str_mv |
2009-06-26 |
dc.date.accessioned.fl_str_mv |
2016-01-26T18:55:29Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009. |
dc.identifier.uri.fl_str_mv |
http://bdtd.unoeste.br:8080/tede/handle/tede/229 |
identifier_str_mv |
VIEL, Rosilene Martins. Fenoterol and Salbutamol inalatory road in dogs: clinical, laboratorial and eletrocardiograpy aspects. 2009. 29 f. Dissertação (Mestrado em Ciências Agrárias) - Universidade do Oeste Paulista, Presidente Prudente, 2009. |
url |
http://bdtd.unoeste.br:8080/tede/handle/tede/229 |
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por |
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1886725639743614135 |
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500 |
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openAccess |
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Universidade do Oeste Paulista |
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Mestrado em Ciência Animal |
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UNOESTE |
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BR |
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Ciências Agrárias |
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Universidade do Oeste Paulista |
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