Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study

Detalhes bibliográficos
Ano de defesa: 2020
Autor(a) principal: Kato, Renata Mayumi
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: eng
Instituição de defesa: Biblioteca Digitais de Teses e Dissertações da USP
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Cone-beam computed tomography
Disostose mandibulofacial
Mandibulofacial dysostosis
Pierre Robin Syndrome
Síndrome de Pierre Robin
Tomografia computadorizada de feixe cônico
Link de acesso: https://www.teses.usp.br/teses/disponiveis/61/61132/tde-02102020-112940/
Resumo: Introduction: Treacher Collins Syndrome (TCS) and non-syndromic Pierre Robin Sequence (PRS) share mandibular deficiency as a similar clinical finding. The ramus-body ratio, the degree of mandibular asymmetry and the condyle morphology were not compared between TCS and PRS. Objectives: The aim of this study was to compare the facial morphology and mandibular dimensions in individuals with TCS and PRS. Methods: The sample consisted of cone-beam computed tomography (CBCT) from a single center. Group TCS was composed by 17 individuals with TCS and presented an average age of 11.5 years (7 males, 10 females). Group PRS was paired by sex and age with the Group TCS. Quantitative evaluations were performed using CBCT-derived cephalometric reconstructions (2D) and three-dimensional reconstructions of the mandible. The softwares used was Dolphin (Dolphin Imaging 11.0 & Management Solutions, California, United States) and Mimics Innovation Suite 17.0 (Materialize, Leuven, Belgium). Intergroup comparison was performed using the independent t test/Mann-Whitney and the ANOVA/Tukey test for twodimensional and three-dimensional analysis, respectively (p <0.05). Results: The cranial base and the sagittal position of the maxilla were similar in both groups. The mandible in group TCS showed a higher degree of asymmetry than group PRS. The transversal dimensions of the mandibular ramus and condyle, the effective mandibular and mandibular body length and the condyle height were reduced in TCS compared PRS. Group TCS exhibited a greater gonial angle with a more severe vertical growth pattern when compared to PRS. Conclusion: The most important dentoskeletal differences between the craniofacial anomalies were observed in the mandible. Treacher Collins Syndrome had a smaller, more asymmetrical and more vertical mandible than the non-syndromic Pierre Robin Sequence
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spelling Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT studyComparação entre Síndrome de Treacher Collins e Sequência de Robin Isolada: um estudo com TCFCCone-beam computed tomographyDisostose mandibulofacialMandibulofacial dysostosisPierre Robin SyndromeSíndrome de Pierre RobinTomografia computadorizada de feixe cônicoIntroduction: Treacher Collins Syndrome (TCS) and non-syndromic Pierre Robin Sequence (PRS) share mandibular deficiency as a similar clinical finding. The ramus-body ratio, the degree of mandibular asymmetry and the condyle morphology were not compared between TCS and PRS. Objectives: The aim of this study was to compare the facial morphology and mandibular dimensions in individuals with TCS and PRS. Methods: The sample consisted of cone-beam computed tomography (CBCT) from a single center. Group TCS was composed by 17 individuals with TCS and presented an average age of 11.5 years (7 males, 10 females). Group PRS was paired by sex and age with the Group TCS. Quantitative evaluations were performed using CBCT-derived cephalometric reconstructions (2D) and three-dimensional reconstructions of the mandible. The softwares used was Dolphin (Dolphin Imaging 11.0 & Management Solutions, California, United States) and Mimics Innovation Suite 17.0 (Materialize, Leuven, Belgium). Intergroup comparison was performed using the independent t test/Mann-Whitney and the ANOVA/Tukey test for twodimensional and three-dimensional analysis, respectively (p <0.05). Results: The cranial base and the sagittal position of the maxilla were similar in both groups. The mandible in group TCS showed a higher degree of asymmetry than group PRS. The transversal dimensions of the mandibular ramus and condyle, the effective mandibular and mandibular body length and the condyle height were reduced in TCS compared PRS. Group TCS exhibited a greater gonial angle with a more severe vertical growth pattern when compared to PRS. Conclusion: The most important dentoskeletal differences between the craniofacial anomalies were observed in the mandible. Treacher Collins Syndrome had a smaller, more asymmetrical and more vertical mandible than the non-syndromic Pierre Robin SequenceIntrodução: A Síndrome de Treacher Collins (STC) e a Sequência de Robin Isolada (SR) compartilham a deficiência mandibular como um achado clínico similar. A proporção ramocorpo, o grau de assimetria mandibular e a morfologia dos côndilos ainda não foram comparadas entre a SR e a STC. Objetivos: O objetivo deste estudo foi comparar a morfologia da face e dimensões da mandíbula em indivíduos com STC e SR. Métodos: A amostra consistiu de tomografias computadorizadas de feixe cônico (TCFC) provenientes do arquivo do HRAC-USP. O Grupo STC foi composto por 17 indivíduos com STC e apresentava idade média de 11,5 anos (7 do sexo masculino, 10 do sexo feminino). O Grupo SR foi pareado por sexo e idade com o grupo STC. Avaliações quantitativas foram realizadas em reconstruções da telerradiografia (2D) e tridimensionais da mandíbula. Os softwares utilizados foram Dolphin (Dolphin Imaging 11.0 & Management Solutions, California, United States) e Mimics Innovation Suite 17.0 (Materialize, Leuven, Belgium). A comparação intergrupos foi realizada por meio do teste t independente/Mann-Whitney e do teste ANOVA e Tukey para a análise bidimensional e tridimensional, respectivamente (p<0.05). Resultados: A base do crânio e a posição sagital da maxila foram similares entre os grupos. A mandíbula na STC demonstrou maior grau de assimetria que a SR. As dimensões transversais do ramo e do côndilo, os comprimentos efetivo da mandíbula e do corpo mandibular e a altura do côndilo mostraram-se reduzidos no grupo STC em relação ao grupo SR. O grupo STC exibiu um ângulo goníaco mais aberto com maior tendência ao crescimento vertical quando comparada à SR. Conclusão: As diferenças dentoesqueléticas mais marcantes entre as duas síndromes foram encontradas na mandíbula. A síndrome de Treacher Collins apresentou uma mandíbula menor, mais assimétrica e mais vertical que a sequência de Pierre Robin IsoladaBiblioteca Digitais de Teses e Dissertações da USPCarreira, Daniela Gamba GaribKato, Renata Mayumi2020-03-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://www.teses.usp.br/teses/disponiveis/61/61132/tde-02102020-112940/reponame:Biblioteca Digital de Teses e Dissertações da USPinstname:Universidade de São Paulo (USP)instacron:USPLiberar o conteúdo para acesso público.info:eu-repo/semantics/openAccesseng2024-10-09T13:16:04Zoai:teses.usp.br:tde-02102020-112940Biblioteca Digital de Teses e Dissertaçõeshttp://www.teses.usp.br/PUBhttp://www.teses.usp.br/cgi-bin/mtd2br.plvirginia@if.usp.br|| atendimento@aguia.usp.br||virginia@if.usp.bropendoar:27212024-10-09T13:16:04Biblioteca Digital de Teses e Dissertações da USP - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
Comparação entre Síndrome de Treacher Collins e Sequência de Robin Isolada: um estudo com TCFC
title Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
spellingShingle Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
Kato, Renata Mayumi
Cone-beam computed tomography
Disostose mandibulofacial
Mandibulofacial dysostosis
Pierre Robin Syndrome
Síndrome de Pierre Robin
Tomografia computadorizada de feixe cônico
title_short Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
title_full Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
title_fullStr Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
title_full_unstemmed Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
title_sort Comparison of Treacher Collins Syndrome and Pierre Robin Sequence: a CBCT study
author Kato, Renata Mayumi
author_facet Kato, Renata Mayumi
author_role author
dc.contributor.none.fl_str_mv Carreira, Daniela Gamba Garib
dc.contributor.author.fl_str_mv Kato, Renata Mayumi
dc.subject.por.fl_str_mv Cone-beam computed tomography
Disostose mandibulofacial
Mandibulofacial dysostosis
Pierre Robin Syndrome
Síndrome de Pierre Robin
Tomografia computadorizada de feixe cônico
topic Cone-beam computed tomography
Disostose mandibulofacial
Mandibulofacial dysostosis
Pierre Robin Syndrome
Síndrome de Pierre Robin
Tomografia computadorizada de feixe cônico
description Introduction: Treacher Collins Syndrome (TCS) and non-syndromic Pierre Robin Sequence (PRS) share mandibular deficiency as a similar clinical finding. The ramus-body ratio, the degree of mandibular asymmetry and the condyle morphology were not compared between TCS and PRS. Objectives: The aim of this study was to compare the facial morphology and mandibular dimensions in individuals with TCS and PRS. Methods: The sample consisted of cone-beam computed tomography (CBCT) from a single center. Group TCS was composed by 17 individuals with TCS and presented an average age of 11.5 years (7 males, 10 females). Group PRS was paired by sex and age with the Group TCS. Quantitative evaluations were performed using CBCT-derived cephalometric reconstructions (2D) and three-dimensional reconstructions of the mandible. The softwares used was Dolphin (Dolphin Imaging 11.0 & Management Solutions, California, United States) and Mimics Innovation Suite 17.0 (Materialize, Leuven, Belgium). Intergroup comparison was performed using the independent t test/Mann-Whitney and the ANOVA/Tukey test for twodimensional and three-dimensional analysis, respectively (p <0.05). Results: The cranial base and the sagittal position of the maxilla were similar in both groups. The mandible in group TCS showed a higher degree of asymmetry than group PRS. The transversal dimensions of the mandibular ramus and condyle, the effective mandibular and mandibular body length and the condyle height were reduced in TCS compared PRS. Group TCS exhibited a greater gonial angle with a more severe vertical growth pattern when compared to PRS. Conclusion: The most important dentoskeletal differences between the craniofacial anomalies were observed in the mandible. Treacher Collins Syndrome had a smaller, more asymmetrical and more vertical mandible than the non-syndromic Pierre Robin Sequence
publishDate 2020
dc.date.none.fl_str_mv 2020-03-23
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.teses.usp.br/teses/disponiveis/61/61132/tde-02102020-112940/
url https://www.teses.usp.br/teses/disponiveis/61/61132/tde-02102020-112940/
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv
dc.rights.driver.fl_str_mv Liberar o conteúdo para acesso público.
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Liberar o conteúdo para acesso público.
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv
dc.publisher.none.fl_str_mv Biblioteca Digitais de Teses e Dissertações da USP
publisher.none.fl_str_mv Biblioteca Digitais de Teses e Dissertações da USP
dc.source.none.fl_str_mv
reponame:Biblioteca Digital de Teses e Dissertações da USP
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Biblioteca Digital de Teses e Dissertações da USP
collection Biblioteca Digital de Teses e Dissertações da USP
repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da USP - Universidade de São Paulo (USP)
repository.mail.fl_str_mv virginia@if.usp.br|| atendimento@aguia.usp.br||virginia@if.usp.br
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