Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo

Detalhes bibliográficos
Ano de defesa: 2020
Autor(a) principal: Silva, Marcelo de Souza
Orientador(a): Não Informado pela instituição
Banca de defesa: Não Informado pela instituição
Tipo de documento: Dissertação
Tipo de acesso: Acesso aberto
Idioma: por
Instituição de defesa: Universidade Positivo
Brasil
Pós-Graduação
Programa de Pós-Graduação em Biotecnologia Industrial
UP
Programa de Pós-Graduação: Não Informado pela instituição
Departamento: Não Informado pela instituição
País: Não Informado pela instituição
Palavras-chave em Português:
Link de acesso: https://repositorio.cruzeirodosul.edu.br/handle/123456789/2294
Resumo: Introduction: Gastrointestinal tumors are the second leading cause of cancer death worldwide, with about 990,000 new cases per year and 738,000 deaths. According to the National Cancer Institute (INCA), the incidence of tumors of the digestive tract was approximately 57,670 cases in 2018, 21,290 of which were gastric cancer. In 2017, there were 14,314 cases of gastric cancer. Adenocarcinoma is the histological type responsible for 95% of gastrointestinal cancer cases. Treatment will depend on the degree of spread. This pathology is studied by therapeutic endoscopy, which with its innovations enables early and efficient diagnosis and treatment. The treatment consists of dissecting the tumor under it, dissecting the submucosa, removing the first layer of the digestive tract, however this procedure can have complications such as bleeding and perforation, due to the difficulty in visualizing the vessels and the depth of the lesion during the dissection. Objective: Study the devices that assist in the endoscopic resection of the stomach and develop a prototype with this function. Methods: The first article reviews the past 20 years about endoscopic gastric tumor resection devices developed with the function of gastric resections. The second article corresponds to the process of developing a prototype seeking to improve the functions of the prototypes developed today. Results and discussion :The first proved to be of an inadequate size for the delicacy that this type of resection required, errors that were corrected in the second prototype, but other specific situations specific to the development of the medical clamp prototype appeared as the lack of adequate steel cables, making the movements of the robotic prototype. A third prototype was designed that is believed to correct all the flaws that were identified in the previous two prototypes, however due to many difficulties from projects to raw materials it was not prototyped, however it is believed that this prototype will be the solution for improve the resection of gastric tumors. Conclusion: After two prototypes with countless difficulties, we believe that we were able to design the third with the solution, but it was not possible to prototype it.
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spelling Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivoBiotecnologia industrialTrato gastrointestinal - NeoplasiasDissecçãoRessecção endoscópica de mucosaCNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERALIntroduction: Gastrointestinal tumors are the second leading cause of cancer death worldwide, with about 990,000 new cases per year and 738,000 deaths. According to the National Cancer Institute (INCA), the incidence of tumors of the digestive tract was approximately 57,670 cases in 2018, 21,290 of which were gastric cancer. In 2017, there were 14,314 cases of gastric cancer. Adenocarcinoma is the histological type responsible for 95% of gastrointestinal cancer cases. Treatment will depend on the degree of spread. This pathology is studied by therapeutic endoscopy, which with its innovations enables early and efficient diagnosis and treatment. The treatment consists of dissecting the tumor under it, dissecting the submucosa, removing the first layer of the digestive tract, however this procedure can have complications such as bleeding and perforation, due to the difficulty in visualizing the vessels and the depth of the lesion during the dissection. Objective: Study the devices that assist in the endoscopic resection of the stomach and develop a prototype with this function. Methods: The first article reviews the past 20 years about endoscopic gastric tumor resection devices developed with the function of gastric resections. The second article corresponds to the process of developing a prototype seeking to improve the functions of the prototypes developed today. Results and discussion :The first proved to be of an inadequate size for the delicacy that this type of resection required, errors that were corrected in the second prototype, but other specific situations specific to the development of the medical clamp prototype appeared as the lack of adequate steel cables, making the movements of the robotic prototype. A third prototype was designed that is believed to correct all the flaws that were identified in the previous two prototypes, however due to many difficulties from projects to raw materials it was not prototyped, however it is believed that this prototype will be the solution for improve the resection of gastric tumors. Conclusion: After two prototypes with countless difficulties, we believe that we were able to design the third with the solution, but it was not possible to prototype it.Introdução:. Os tumores gastrointestinais são a segunda causa de morte por câncer no mundo, com cerca de 990.000 novos casos por ano e 738.000 óbitos. Segundo o Instituto Nacional do Câncer (INCA), a incidência de tumores do trato digestório foi de aproximadamente 57.670 casos em 2018, com 21.290 de câncer gástrico. O tratamento dependerá do grau da disseminação. Essa patologia é estudada pela endoscopia terapêutica, que, com suas inovações, possibilita o diagnóstico e tratamento precoce e eficiente. O tratamento consiste na dissecção do tumor por baixo dele, dissecando a submucosa, retirando a primeira camada do trato digestório, porém este procedimento pode ter complicações como sangramento e perfuração, devido à dificuldade de visualização dos vasos e da profundidade da lesão durante a dissecção. Objetivo: Estudar os dispositivos que auxiliem na ressecção endoscópicas do estômago e desenvolver um protótipo com esta função. Metodologia: O primeiro artigo faz revisão dos últimos 20 anos sobre os dispositivos de ressecção endoscópica de tumores gástricos desenvolvidos com a função de ressecções gástricas. O segundo artigo corresponde ao processo de desenvolvimento de um protótipo procurando melhorar as funções dos protótipos desenvolvidos hoje. Resultados e Discussão: O primeiro protótipo se mostrou de tamanho inadequado para a delicadeza que este tipo de ressecção exige, erros que, no segundo protótipo, foram corrigidos, porém outras situações especificas próprias do desenvolvimento do protótipo de pinça médica foram aparecendo como a falta de cabos de aço adequados, tornando os movimentos do protótipo robotizados. Foi projetado um terceiro protótipo que tem potencial para corrigi todas as falhas que foram identificadas nos dois protótipos anteriores. Conclusão: Depois de dois protótipos com falha no desenvolvimento, acreditamos que conseguiremos projetar o terceiro com a solução.Universidade PositivoBrasilPós-GraduaçãoPrograma de Pós-Graduação em Biotecnologia IndustrialUPLoureiro, Marcelo de Paulahttp://lattes.cnpq.br/5025639174188548Silva, Marcelo de Souza2021-05-28T17:57:52Z20202021-05-28T17:57:52Z2020info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://repositorio.cruzeirodosul.edu.br/handle/123456789/2294porinfo:eu-repo/semantics/openAccessreponame:Repositório do Centro Universitário Braz Cubasinstname:Centro Universitário Braz Cubas (CUB)instacron:CUB2021-05-28T18:03:50Zoai:repositorio.cruzeirodosul.edu.br:123456789/2294Repositório InstitucionalPUBhttps://repositorio.brazcubas.edu.br/oai/requestbibli@brazcubas.edu.bropendoar:2021-05-28T18:03:50Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)false
dc.title.none.fl_str_mv Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
title Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
spellingShingle Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
Silva, Marcelo de Souza
Biotecnologia industrial
Trato gastrointestinal - Neoplasias
Dissecção
Ressecção endoscópica de mucosa
CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
title_short Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
title_full Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
title_fullStr Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
title_full_unstemmed Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
title_sort Desenvolvimento de protótipo de pinça endoscopica para auxiliar a ressecção de lesão do tubo digestivo
author Silva, Marcelo de Souza
author_facet Silva, Marcelo de Souza
author_role author
dc.contributor.none.fl_str_mv Loureiro, Marcelo de Paula
http://lattes.cnpq.br/5025639174188548
dc.contributor.author.fl_str_mv Silva, Marcelo de Souza
dc.subject.por.fl_str_mv Biotecnologia industrial
Trato gastrointestinal - Neoplasias
Dissecção
Ressecção endoscópica de mucosa
CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
topic Biotecnologia industrial
Trato gastrointestinal - Neoplasias
Dissecção
Ressecção endoscópica de mucosa
CNPQ::CIENCIAS BIOLOGICAS::BIOLOGIA GERAL
description Introduction: Gastrointestinal tumors are the second leading cause of cancer death worldwide, with about 990,000 new cases per year and 738,000 deaths. According to the National Cancer Institute (INCA), the incidence of tumors of the digestive tract was approximately 57,670 cases in 2018, 21,290 of which were gastric cancer. In 2017, there were 14,314 cases of gastric cancer. Adenocarcinoma is the histological type responsible for 95% of gastrointestinal cancer cases. Treatment will depend on the degree of spread. This pathology is studied by therapeutic endoscopy, which with its innovations enables early and efficient diagnosis and treatment. The treatment consists of dissecting the tumor under it, dissecting the submucosa, removing the first layer of the digestive tract, however this procedure can have complications such as bleeding and perforation, due to the difficulty in visualizing the vessels and the depth of the lesion during the dissection. Objective: Study the devices that assist in the endoscopic resection of the stomach and develop a prototype with this function. Methods: The first article reviews the past 20 years about endoscopic gastric tumor resection devices developed with the function of gastric resections. The second article corresponds to the process of developing a prototype seeking to improve the functions of the prototypes developed today. Results and discussion :The first proved to be of an inadequate size for the delicacy that this type of resection required, errors that were corrected in the second prototype, but other specific situations specific to the development of the medical clamp prototype appeared as the lack of adequate steel cables, making the movements of the robotic prototype. A third prototype was designed that is believed to correct all the flaws that were identified in the previous two prototypes, however due to many difficulties from projects to raw materials it was not prototyped, however it is believed that this prototype will be the solution for improve the resection of gastric tumors. Conclusion: After two prototypes with countless difficulties, we believe that we were able to design the third with the solution, but it was not possible to prototype it.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020
2021-05-28T17:57:52Z
2021-05-28T17:57:52Z
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dc.publisher.none.fl_str_mv Universidade Positivo
Brasil
Pós-Graduação
Programa de Pós-Graduação em Biotecnologia Industrial
UP
publisher.none.fl_str_mv Universidade Positivo
Brasil
Pós-Graduação
Programa de Pós-Graduação em Biotecnologia Industrial
UP
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reponame_str Repositório do Centro Universitário Braz Cubas
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